"Both hemp and marijuana also have separate definitions in statute. While marijuana is defined in U.S. drug laws, Congress established a statutory definition for industrial hemp as “the plant Cannabis sativa L. and any part of such plant, whether growing or not, with a delta-9 tetrahydrocannabinol concentration of not more than 0.3 percent on a dry weight basis” as part of the 2014 farm bill.4 Hemp is generally characterized by plants that are low in delta-9 tetrahydrocannabinol (delta-9 THC), the dominant psychotrophic ingredient in Cannabis sativa.5
Hello. I have stage 4 thyroid, secondary lymphoma..And many other health issues.I use 50mg of cbd vapor oil. 5 drops with each use. Total equals 250mg, about hits per dose, three times a day. I'm also on subsys, which is fentanyl. Idk about anyone but myself, but it's helped me with pain, with sleep, and in general my moods. So I dint have anything negative to say. I just hope that with time, proper diet, low dose chemo, and some other herbal usage, that I can shirk some of the cancer eating at my body... Thanks and good luck to you all.
Hemp is the non THC variety of the Cannabis Sativa plant.  Hemp and marijuana are often confused, learn more about the difference on our hemp vs. marijuana page. The fiber, seeds and oil are incredible valuable and is why hemp is often called a “cash crop”.  Hemp is a very hearty plant and grows very quickly in very diverse soil conditions.  Cultivation of hemp for industrial purposes has been done by many civilizations for over 12,000 years.   Industrial hemp was the desired fiber used to manufacture rope, canvas, paper, and clothing until alternative textiles and synthetics for these purposes were discovered.  Although China has been the largest hemp producer over the years, other countries such as Australia and Canada are catching up.  It has been illegal for anyone to grow hemp in the United States as hemp is illegal under the marijuana prohibition act but Colorado has changed the laws and paved the way for industrial hemp production again in the United States(see hemp history). Now hemp oils, CBD, hemp plastics, hemp building materials and many hemp fiber products can be seen and purchased on the market. Hemp is truly an amazing plant with the potential to help “green up” many industries.
From 1982 to 2002 the EU provided the equivalent of about 50 million dollars to develop new flax and hemp harvesting and fiber processing technologies (Karus et al. 2000). Because of the similarities of flax and hemp, the technologies developed for one usually are adaptable to the other. In addition, various European nations and private firms contributed to the development of hemp technologies. Accordingly, Europe is far more advanced in hemp development with respect to all fiber-based applications than other parts of the world. The EU currently dedicates about 30,000 ha to hemp production. France is the leading country in hemp cultivation in the EU, and 95% of the non-seed production is used for “specialty pulp” as described below. Harvesting and processing machinery for fiber hemp is highly advanced in Europe, and some has been imported into Canada. However, there is insufficient fiber processing capacity to handle hemp produced in Canada.
Tammy et al, Through trial and error you will find a correct dosage. Try 50 mg daily....25 each 2x daily....if no results up the dosage until it works for you. Remember, there has never been a death from marijuana or CBD use. You might want to try a tincture or rub with CBD and THC. You won't get the psych high from it. Helps my friend with PArkinsons tremors. She takes 50mg of tincture and uses the rub morning and night. It is a miracle for arthritis. Good luck
Last year, the National Academies of Sciences, Engineering and Medicine released a nearly 500-page report on the health effects of cannabis and cannabinoids. A committee of 16 experts from a variety of scientific and medical fields analyzed the available evidence — more than 10,000 scientific abstracts in all. Because so few studies examine the effects of CBD on its own, the panel did not issue any findings about CBD specifically, but it did reach some conclusions about cannabis and cannabinoids more generally. The researchers determined that there is “conclusive or substantial evidence” supporting the use of cannabis or cannabinoids for chronic pain in adults, multiple sclerosis-related spasticity (a kind of stiffness and muscle spasms), and chemotherapy-induced nausea and vomiting. The committee also found “moderate” evidence that cannabis or cannabinoids can reduce sleep disturbances in people with obstructive sleep apnea, fibromyalgia, chronic pain and multiple sclerosis, as well as “limited” evidence that these substances can improve symptoms of Tourette’s syndrome, increase appetite and stem weight loss in people with HIV/AIDs, and improve symptoms of PTSD and anxiety.
"Skin dryness and itchiness, in particular, are very serious problems in atopic dermatitis, which often lead to additional complications, such as opportunistic infections. In any event, it seems that the reduction of atopic symptomology observed in this study is a direct result of ingested hempseed oil. These preliminary results confirm anecdotal observations of improved skin quality after ingesting modest amounts of hempseed oil on a daily basis over a relatively short period of time."
A 2011 study evaluated the effects of two non-psychoactive cannabinoids, cannabidiol (CBD) and cannabichromene (CBC), on pain management. The study concluded that, “CBD and CBC stimulated descending pathways of antinociception and caused analgesia by interacting with several target proteins involved in nociceptive control. These compounds might represent useful therapeutic agents with multiple mechanisms of action.”
CBC is another lesser-known yet still crucial cannabinoid in marijuana, especially from a therapeutic perspective. While bereft of the psychoactive quality of THC (and to a lesser extent THCV), CBC is gaining popularity as an anxiety reducer. While research on cannabichromene lags behind others, there’s good reason to continue looking into its potential as a medicine.

The psychoactive effects of cannabis are known to have a triphasic nature. Primary psychoactive effects include a state of relaxation, and to a lesser degree, euphoria from its main psychoactive compound, tetrahydrocannabinol. Secondary psychoactive effects, such as a facility for philosophical thinking, introspection and metacognition have been reported among cases of anxiety and paranoia.[94] Finally, the tertiary psychoactive effects of the drug cannabis, can include an increase in heart rate and hunger, believed to be caused by 11-OH-THC, a psychoactive metabolite of THC produced in the liver.
To decide between these hypotheses, we need evidence that cannabis use preceded the psychosis; that plausible alternative explanations based on confounding can be excluded (Hall, 1987). The best evidence for answering these questions comes from longitudinal population-based studies that have assessed cannabis use before the onset of psychotic symptoms, followed the cohort over a substantial period and used statistical methods to assess the contribution of a variety of factors other than cannabis use that may explain the relationship (Macleod et al., 2004).
A 2012 review found that the THC content in marijuana had increased worldwide from 1970 to 2009.[160] It is unclear, however, whether the increase in THC content has caused people to consume more THC or if users adjust based on the potency of the cannabis. It is likely that the higher THC content allows people to ingest less tar. At the same time, CBD levels in seized samples have lowered, in part because of the desire to produce higher THC levels and because more illegal growers cultivate indoors using artificial lights. This helps avoid detection but reduces the CBD production of the plant.[161]
Over the ages, countless innovations have attempted to improve on the basic experience of inhaling the smoke of combusted cannabis. As a result, there are numerous ways to smoke marijuana. The rolling technique is at the root of joints, blunts, and spliffs. On the other hand, glassware and other devices are essential for smoking weed out of a pipe, bong, or bubbler.
Unlike THC, which primarily binds to CB-1 receptors located in the brain, CBD works in the body by manipulating receptors throughout organ tissues, the immune system, the pain response system, the hormonal system, and other whole-body regulatory systems. Basically, since its receptors have been found to exist in virtually every cell and tissue type in the body, CBD is believed to work on every aspect of human health and behavior – from the subcellular level to the whole-body leve and beyond.
I always tell beginners for CBD use to use full-spectrum. The full-spectrum oils contain a lot of terpenes and other good stuff along with CBD and help much more when you suffer from anxiety attacks. CBDistillery also has a wide range of potencies to choose from. Unlike, FabCBD, which offers only limited capacities, CBDistillery’s oils go up to 5000mg per bottle and it is indeed one of the best CBD oils for pain in the market
As noted above, hemp seed cake makes an excellent feed for animals. However, feeding entire plants is another matter, because the leaves are covered with the resin-producing glands. While deer, groundhogs, rabbits, and other mammals will nibble on hemp plants, mammals generally do not choose to eat hemp. Jain and Arora (1988) fed narcotic Cannabis refuse to cattle, and found that the animals “suffered variable degrees of depression and revealed incoordination in movement.” By contrast, Letniak et al. (2000) conducted an experimental trial of hemp as silage. No significant differences were found between yield of the hemp and of barley/oat silage fed to heifers, suggesting that fermenting hemp plants reduces possible harmful constituents.
The Cannabis plant has a history of medicinal use dating back thousands of years across many cultures.[111] The Yanghai Tombs, a vast ancient cemetery (54 000 m2) situated in the Turfan district of the Xinjiang Uyghur Autonomous Region in northwest China, have revealed the 2700-year-old grave of a shaman. He is thought to have belonged to the Jushi culture recorded in the area centuries later in the Hanshu, Chap 96B.[112] Near the head and foot of the shaman was a large leather basket and wooden bowl filled with 789g of cannabis, superbly preserved by climatic and burial conditions. An international team demonstrated that this material contained tetrahydrocannabinol, the psychoactive component of cannabis. The cannabis was presumably employed by this culture as a medicinal or psychoactive agent, or an aid to divination. This is the oldest documentation of cannabis as a pharmacologically active agent.[113]

Phytocannabinoids are lipid soluble with slow and erratic oral absorption. While cannabis users claim that the smoking of cannabis allows easy dose titration as a function of rapid onset, high serum levels in a short interval inevitably result. This quick onset is desirable for recreational purposes, wherein intoxication is the ultimate goal, but aside from paroxysmal disorders (eg, episodic trigeminal neuralgia or cluster headache attack), such rapid onset of activity is not usually necessary for therapeutic purposes in chronic pain states. As more thoroughly reviewed elsewhere (Russo 2006b), cannabis smoking produces peak levels of serum THC above 140 ng/mL (Grotenhermen 2003; Huestis et al 1992), while comparable amounts of THC in Sativex administered oromucosally remained below 2 ng/mL (Guy and Robson 2003).
As noted above, hemp seed cake makes an excellent feed for animals. However, feeding entire plants is another matter, because the leaves are covered with the resin-producing glands. While deer, groundhogs, rabbits, and other mammals will nibble on hemp plants, mammals generally do not choose to eat hemp. Jain and Arora (1988) fed narcotic Cannabis refuse to cattle, and found that the animals “suffered variable degrees of depression and revealed incoordination in movement.” By contrast, Letniak et al. (2000) conducted an experimental trial of hemp as silage. No significant differences were found between yield of the hemp and of barley/oat silage fed to heifers, suggesting that fermenting hemp plants reduces possible harmful constituents.
Can cannabis help treat psoriasis? The active cannabinoids in cannabis may be an effective treatment for psoriasis. Research shows that they offer potential health benefits that could relieve the symptoms of psoriasis. They may be able to reduce inflammation and itching, control pain, and even heal wounds. Learn more about cannabis for psoriasis here. Read now

This guide is an introduction to anyone looking to inform themselves about the reality of cannabis. It covers basic information about the marijuana plant, cannabis preparations, and the crucial elements of plant anatomy and science. This guide to marijuana also gives an overview of the most popular medical and recreational uses of cannabis. It offers a survey of the most important medical cannabis research while highlighting emerging trends in the legal cannabis market. The guide also introduces those new to cannabis to the many ways to consume marijuana, and much more.
"Approximately 30 countries in Europe, Asia, and North and South America currently permit farmers to grow hemp. Some of these countries never outlawed production, while some countries banned production for certain periods in the past. China is among the largest producing and exporting countries of hemp textiles and related products, as well as a major supplier of these products to the United States. The European Union (EU) has an active hemp market, with production in most member nations. Production is centered in France, the United Kingdom, Romania, and Hungary.30
CBD and THC interact with our bodies in a variety of ways. One of the main ways they impact us is by mimicking and augmenting the effects of the compounds in our bodies called “endogenous cannabinoids” - so named because of their similarity to the compounds found in the cannabis plant. These “endocannabinoids” are part of a regulatory system called the “endocannabinoid system”.
So true. Hearst and Rockefeller did not want Hemp or any form of Cannabis interfering with their lucrative paper, pharmaceutical and oil industries. Hemp is versatile and renewable. It can be used for food, medicine, fuel, paper, clothing, plastic, building materials; just about anything paper and oil is used for. These bastard wealthy people have done a disservice to all people and for the sake of lining their already copiously rich pockets. They and those like them are criminals of the worst order

"The global market for hemp consists of more than 25,000 products in nine submarkets: agriculture, textiles, recycling, automotive, furniture, food and beverages, paper, construction materials, and personal care (Table 1). Hemp can be grown as a fiber, seed, or dual-purpose crop.6 The stalk and seed are the harvested products. The interior of the stalk has short woody fibers called hurds; the outer portion has long bast fibers. Hemp seed/grains are smooth and about one-eighth to one-fourth of an inch long.7
We need proper studies, the panel concluded, on the health effects of cannabis on children and teen-agers and pregnant women and breast-feeding mothers and “older populations” and “heavy cannabis users”; in other words, on everyone except the college student who smokes a joint once a month. The panel also called for investigation into “the pharmacokinetic and pharmacodynamic properties of cannabis, modes of delivery, different concentrations, in various populations, including the dose-response relationships of cannabis and THC or other cannabinoids.”

Like everything else in the U.S it is buyer beware. I was told that the 30 dollar a bottle Hemp Oil, would not work becasue I was “Skeptical.” I had asked exactly these questions at a Dispensary. The CBD Craze is mostly hype. It does little or nothing for pain, or anything else. The only thing I have seen is that when it is derived from marijuana in the for of a Salve with the a small amount of THC in it, it might help with arthritis topically.
I use cbd oil every day. I refuse to go without it. I have no arthritic pain at all anymore. I had a hip replacement 3 years ago. I am in need of the other one to be replaced. I was laying awake crying at night because of my hip pain. After I started using the oil my hip has quit aching. I sometimes forget I even have a problem with it or my arthritis. Had I known about the oil before I had my hip replaced I never would have had the surgery. I am pain free. I use hemp oil. There are 20 mg of cannabiniol in each 1 ml dose.
While the science behind CBD oil assuaged many of my concerns, Charlotte Figi's inspiring story was the kicker. Figi, a 6-year-old girl diagnosed with a rare and resistant form of epilepsy known as Dravet syndrome, was actually placed on hospice care and given a "do not resuscitate" order when her parents, desperate and frustrated with pharmaceutical medication, considered medical marijuana. Charlotte is now 99% seizure-free since she began supplementing with Charlotte Web's CBD oil, which the brand named after Figi.
In a SAFEX study of Phase III double-blind RCT in 160 subjects with various symptoms of MS (Wade et al 2004), 137 patients elected to continue on Sativex after the initial study (Wade et al 2006). Rapid declines were noted in the first twelve weeks in pain VAS (N = 47) with slower sustained improvements for more than one year. During that time, there was no escalation of dose indicating an absence of tolerance to the preparation. Similarly, no withdrawal effects were noted in a subset of patients who voluntarily stopped the medicine abruptly. Upon resumption, benefits resumed at the prior established dosages.
Hemp rope was used in the age of sailing ships, though the rope had to be protected by tarring, since hemp rope has a propensity for breaking from rot, as the capillary effect of the rope-woven fibers tended to hold liquid at the interior, while seeming dry from the outside.[44] Tarring was a labor-intensive process, and earned sailors the nickname "Jack Tar". Hemp rope was phased out when manila rope, which does not require tarring, became widely available. Manila is sometimes referred to as Manila hemp, but is not related to hemp; it is abacá, a species of banana.
Soil characteristics, latitude and climatic stresses have been found to have significant effects on THC concentrations, and there are seasonal and even diurnal variations (Small 1979; Pate 1998b). However, the range of THC concentrations developed by low-THC cultivars (those typically with £0.3% THC) under different circumstances on the whole is limited, for the most part generally not varying more than 0.2 percentage points when grown in a range of circumstances, and usually less (note information in Scheifle et al. 1999; Scheifle 2000, Scheifle and Dragla 2000). Practically, this has meant in Canadian experience that a few cultivars have been eliminated from further commercial cultivation because they sometimes exceed the 0.3% level (‘Fedora 19’ and ‘Futura,’ authorized in 2000, have now been removed because some test results in several years exceeded 0.3%; ‘Finola’ and ‘Uniko B’ are under probation because of elevated levels), but on the whole most of the permitted cultivars have maintained highly consistent development of quite low levels of THC.
At least 38 states considered legislation related to industrial hemp in 2018. These bills ranged from clarifying existing laws to establishing new licensing requirements and programs. At least six states – Alaska, Arizona, Kansas, Missouri, New Jersey and Oklahoma – enacted legislation in 2018 establishing hemp research and industrial hemp pilot programs. Georgia created the House Study Committee on Industrial Hemp Production. States, already allowing for industrial hemp programs, continued to consider policies related to licensure, funding, seed certification, and other issues. For example, Tennessee amended its Commercial Feed Law to include hemp. 
However, if it was sourced from actual marijuana (i.e. cannabis that contains more than 2% THC by volume), then it is technically illegal. Most of the best CBD oils for pain that you find in dispensaries in states like Colorado, California, and Washington (as well as other states where weed is legal) will have been extracted from marijuana plants — not industrial hemp plants. Unfortunately, this means that these products are not allowed to be sold online and shipped across state lines to “non-legal” states.

Although hemp and marijuana are both varieties of cannabis, there is a difference between them. The differences between these cannabis varieties are primarily evident in the way each plant is used. These differences are also documented in the language, laws, and regulations that apply to each variety. In this introduction to hemp, we’ll break down the anatomy, history, use, and legality of the hemp plant to get to the heart of not only what distinguishes it from marijuana, but also what makes it such a viable, versatile commodity.
Even if you live in a state where recreational marijuana is legal, the mainstream sale of CBD in bakeries and coffee shops is still a whole different issue, according to Griffen Thorne, a California-based attorney with Harris Bricken, a firm specializing in cannabis-trade issues. For cannabis, “one of the things that’s a really big requirement in California is safety testing at the distributor level,” Thorne says. “That’s not really there yet for hemp CBD products.” For instance, CBD products sometimes contain enough lingering THC to produce psychoactive effects.
^ Blest-Hopley G, Giampietro V, Bhattacharyya S (May 2018). "Residual effects of cannabis use in adolescent and adult brains - A meta-analysis of fMRI studies". Neuroscience and Biobehavioral Reviews. 88: 26–41. doi:10.1016/j.neubiorev.2018.03.008. PMID 29535069. This may reflect the multitude of cognitive tasks employed by the various studies included in these meta-analyses, all of which involved performing a task thereby requiring the participant to reorient their attention and attempt to solve the problem at hand and suggest that greater engagement of this region indicates less efficient cognitive performance in cannabis users in general, irrespective of their age.
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^ Nadulski T, Pragst F, Weinberg G, Roser P, Schnelle M, Fronk EM, Stadelmann AM (December 2005). "Randomized, double-blind, placebo-controlled study about the effects of cannabidiol (CBD) on the pharmacokinetics of Delta9-tetrahydrocannabinol (THC) after oral application of THC verses standardized cannabis extract". Ther Drug Monit. 27 (6): 799–810. doi:10.1097/01.ftd.0000177223.19294.5c. PMID 16306858.

REM behavior disorder: REM behavior disorder (RBD) is a parasomnia disorder characterized by shouting, becoming physically agitated, or otherwise acting out during sleep. For many, RBD is a symptom of a larger, more serious condition or disorder, such as Alzheimer’s disease or PTSD. CBD oil minimizes the symptoms of RBD, and also alleviates the anxiety and painful symptoms that often accompany disorders that lead to RBD.
I have a brother in law who has been diagnosed with cataplexy and narcoplexy, where he starts quivering and slowly loses control of his body and goes into a sleep, which causes him to drop to the ground with mild seizures while he is out. He lives alone (59 years old), but has smoked cannabis since he (we) were teenagers. He still smokes, and is on medication twice a day for this condition, but if he misses those meds by even half an hour, he is at risk of these seizures. The sad part is, these seizures are usually brought on by the smallest emotional change, usually tension, excitement or, the worst thing, if something he finds funny and is the least bit tickled about and starts to laugh, this process will immediately begin. Does anyone know if this kind of condition is treatable with cbd oil’s or concentrates? As I said, he smokes weed, and often grows his own, but he does it for the high and relaxation advantage, since he is basically home-bound due to this condition ending his work career about 4 years ago. Thanks for any replies. I’d be overjoyed if I could tell him there’s a possible solution to the problem other than his prescriptions. Or even if it worked WITH his meds to keep from having to live such a sedentary life.
The overall effect is not assured because, like cannabis — which is illegal under U.S. federal law although some states have allowed medical or recreational use — states will continue to be able to enact laws related to industrial hemp, allowing for a potential patchwork of legislation across the country. Other questions remain in terms of how exactly the Agriculture Department will regulate the plant.
The US Drug Enforcement Administration’s online criminal justice statistics for 2000 (cscmosaic.albany.edu/sourcebook/1995/pdf/t440.pdf) shows the following seizures and eradication of plants of C. sativa: 40,929 outdoor plots (2,597,796 plants), 139,580,728 ditchweed (ruderal plants), 2,361 indoor operations (217,105 plants), for a grand total of 2,814, 903 plants destroyed. Impressively, the species was grown in all 50 states (including outdoor seizures in every state except Wyoming)! It is of course impossible to know exactly how much marijuana is cultivated in the United States, and perhaps only 10% to 20% of the amount grown is seized. The profitability of the illegal crop is indicated by a comparison of the cost of a bushel of corn (roughly $2.50) and a bushel of manicured marijuana (about $70,000; it has been suggested that prices range from $500 a pound, for low-quality marijuana, to more than $5,000 a pound for “boutique” strains like “Northern Lights” and “Afghan Kush”). According to a National Organization for the Reform of Marijuana Laws (NORML) (mir.drugtext.org/marijuananews/marijuana_ranks_fourth_largest_c.htm) marijuana is at least the fourth most valuable crop in America, outranked only by corn, soybeans, and hay. It was estimated that 8.7 million marijuana plants were harvested in 1997, worth $15.1 billion to growers and $25.2 billion on the retail market (the wholesale value was used to compare marijuana to other cash crops). Marijuana was judged to be the largest revenue producing crop in Alabama, California, Colorado, Hawaii, Kentucky, Maine, Rhode Island, Tennessee, Virginia, and West Virginia, and one of the top five cash crops in 29 other states.
This is not stated to discourage the use of the product because I have read…..some patients have had some efffective relief wth CBD oil but, pain managment is subjective to each individual patient even with opioid medicatios, Research, asking questions is important and the representatives of CBD oil product providers are more than willing to talk to you. There are different ways that the product is extracted from the plant. One in particular seems quite dangerous to me. Read for yourself. Again I do not discourage trying the product. Some, a great deal of patients are even reporting effective pain management with other products such as “kratom”. Again this product is not FDA approved and has no quality control regulation. Word of mouth amd sometimes great reviews but, again pain is subjective to each patient.
"Hemp fields, in fact, could be a deterrent to marijuana growers. A strong case can be made that the best way to reduce the THC level of marijuana grown outdoors would be to grow industrial hemp near it. An experiment in Russia found that hemp pollen could travel 12 kilometers. This would mean that a hemp field would create a zone with a 12-kilometer radius within which no marijuana grower would want to establish a crop.
In Japan, hemp was historically used as paper and a fiber crop. There is archaeological evidence cannabis was used for clothing and the seeds were eaten in Japan back to the Jōmon period (10,000 to 300 BC). Many Kimono designs portray hemp, or asa (Japanese: 麻), as a beautiful plant. In 1948, marijuana was restricted as a narcotic drug. The ban on marijuana imposed by the United States authorities was alien to Japanese culture, as the drug had never been widely used in Japan before. Though these laws against marijuana are some of the world's strictest, allowing five years imprisonment for possession of the drug, they exempt hemp growers, whose crop is used to make robes for Buddhist monks and loincloths for Sumo wrestlers. Because marijuana use in Japan has doubled in the past decade, these exemptions have recently been called into question.[150]
And without high-quality trials, experts don’t know how much is best for a given purpose. The staff at Roth’s dispensary told her, “Try some once or twice a day and see what happens.” (Half a dropper’s worth was a good amount for her.) One thing scientists feel confident about is that CBD is not dangerous. It won’t damage vital organs even at doses as high as 5,000 mg a day, Marcu says, and nobody has died from simply overdosing on a cannabis product.
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But experimental anxiety, which is when stressors are applied to make a volunteer feel anxious for a test, is different than clinical anxiety, and long-term, rigorous clinical trials are necessary to find CBD’s real-life effects on patients. Several are under way right now, including one Blessing is conducting at NYU, but the process of completing those, finding appropriate dosages, and creating a consistent drug that can meet Food and Drug Administration approval standards takes time. “Getting into the full pipeline of FDA approval is probably eight to 10 years away,” Blessing says.
The United Kingdom and Germany resumed commercial production in the 1990s. British production is mostly used as bedding for horses; other uses are under development. Companies in Canada, the UK, the United States, and Germany, among many others, process hemp seed into a growing range of food products and cosmetics; many traditional growing countries still continue to produce textile-grade fibre.
Cannabis use is associated with increased recruitment of task-related areas, such as the dorsolateral prefrontal cortex, which is thought to reflect compensatory activity due to reduced processing efficiency.[114][113][116] Cannabis use is also associated with downregulation of CB1 receptors. The magnitude of down regulation is associated with cumulative cannabis exposure, and is reversed after one month of abstinence.[117][118][119] There is limited evidence that chronic cannabis use can reduce levels of glutamate metabolites in the human brain.[120]
Hemp is plagued by bird predation, which take a heavy toll on seed production. The seeds are well known to provide extremely nutritious food for both wild birds and domestic fowl. Hunters and birdwatchers who discover wild patches of hemp often keep this information secret, knowing that the area will be a magnet for birds in the fall when seed maturation occurs. Increasingly in North America, plants are being established to provide habitat and food for wildlife. Hemp is not an aggressive weed, and certainly has great potential for being used as a wildlife plant. Of course, current conditions forbid such usage in North America.
"The single largest supplier of U.S. imports of raw and processed hemp fiber is China. Other leading country suppliers include Romania, Hungary, India, and other European countries. The single largest source of U.S. imports of hemp seed and oilcake is Canada. The total value of Canada’s exports of hemp seed to the United States has grown significantly in recent years following resolution of a long-standing legal dispute over U.S. imports of hemp foods in late 2004 (see 'Dispute over Hemp Food Imports (1999-2004)'). European countries have also supplied hemp seed and oilcake to the United States."
The Drug Enforcement Agency and the Office of National Drug Control Policy of the US raised concerns over tests conducted from 1995 to 1997 that showed that consumption of hempseed products available during that period led to interference with drug-testing programs for marijuana use. Federal US programs utilize a THC metabolite level of 50 parts per billion in urine. Leson (2000) found that this level was not exceeded by consuming hemp products, provided that THC levels are maintained below 5 ppm in hemp oil, and below 2 ppm in hulled seeds. Nevertheless the presence of even minute trace amounts of THC in foods remains a tool that can be used by those wishing to prevent the hemp oilseed industry from developing.
The phytocannabinoid cannabidiol (CBD), is a non-intoxicating molecule that results from the heating, or decarboxylation, of cannabidiolic acid, or CBDA. As popular as CBD has become in both the cannabis community and mainstream consumerism, its natural precursor, CBDA, is one of 114 unique cannabinoids found in cannabis. In most cultivars, or cultivated varieties of cannabis, CBD ranks low on the expression chart; there often isn’t much. However, following a explosive discovery in 2009 — it was noted that a handful of strains are rich in CBD over THC. Droves of CBD-rich cultivars began cropping up all across the US, resulting in a marked uptick in CBD availability across the states.

A few years ago, the National Academy of Medicine convened a panel of sixteen leading medical experts to analyze the scientific literature on cannabis. The report they prepared, which came out in January of 2017, runs to four hundred and sixty-eight pages. It contains no bombshells or surprises, which perhaps explains why it went largely unnoticed. It simply stated, over and over again, that a drug North Americans have become enthusiastic about remains a mystery.
Preliminary work in Germany (noted in Karus and Leson 1994) suggested that hemp could be grown on soils contaminated with heavy metals, while the fiber remained virtually free of the metals. Kozlowski et al. (1995) observed that hemp grew very well on copper-contaminated soil in Poland (although seeds absorbed high levels of copper). Baraniecki (1997) found similar results. Mölleken et al. (1997) studied effects of high concentration of salts of copper, chromium, and zinc on hemp, and demonstrated that some hemp cultivars have potential application to growth in contaminated soils. It would seem unwise to grow hemp as an oilseed on contaminated soils, but such a habitat might be suitable for a fiber or biomass crop. The possibility of using hemp for bioremediation deserves additional study.
Although marijuana smoke contains a number of carcinogens findings from a limited number of well-designed studies do not suggest an increased risk for the development of either lung or upper airway cancer from light or moderate use. However, the evidence is mixed when it comes to the carcinogenic risks of heavy, long-term marijuana users, according to this study.

The Drug Enforcement Agency and the Office of National Drug Control Policy of the US raised concerns over tests conducted from 1995 to 1997 that showed that consumption of hempseed products available during that period led to interference with drug-testing programs for marijuana use. Federal US programs utilize a THC metabolite level of 50 parts per billion in urine. Leson (2000) found that this level was not exceeded by consuming hemp products, provided that THC levels are maintained below 5 ppm in hemp oil, and below 2 ppm in hulled seeds. Nevertheless the presence of even minute trace amounts of THC in foods remains a tool that can be used by those wishing to prevent the hemp oilseed industry from developing. 

The first of Berenson’s questions concerns what has long been the most worrisome point about cannabis: its association with mental illness. Many people with serious psychiatric illness smoke lots of pot. The marijuana lobby typically responds to this fact by saying that pot-smoking is a response to mental illness, not the cause of it—that people with psychiatric issues use marijuana to self-medicate. That is only partly true. In some cases, heavy cannabis use does seem to cause mental illness. As the National Academy panel declared, in one of its few unequivocal conclusions, “Cannabis use is likely to increase the risk of developing schizophrenia and other psychoses; the higher the use, the greater the risk.” 

Other “minor phytocannabinoids” in cannabis may also contribute relevant activity (McPartland and Russo 2001). Cannabichromene (CBC) is the third most prevalent cannabinoid in cannabis, and is also anti-inflammatory (Wirth et al 1980), and analgesic, if weaker than THC (Davis and Hatoum 1983). Cannabigerol (CBG) displays sub-micromolar affinity for CB1 and CB2 (Gauson et al 2007). It also exhibits GABA uptake inhibition to a greater extent than THC or CBD (Banerjee et al 1975), suggesting possible utilization as a muscle relaxant in spasticity. Furthermore, CBG has more potent analgesic, anti-erythema and lipooxygenase blocking activity than THC (Evans 1991), mechanisms that merit further investigation. It requires emphasis that drug stains of North American (ElSohly et al 2000; Mehmedic et al 2005), and European (King et al 2005) cannabis display relatively high concentrations of THC, but are virtually lacking in CBD or other phytocannabinoid content.

Some manufacturers ship CBD products nationally, an illegal action which the FDA has not enforced in 2018, with CBD remaining the subject of an FDA investigational new drug evaluation, and is not considered legal as a dietary supplement or food ingredient as of December 2018.[70][71] Federal illegality has made it difficult historically to conduct research on CBD.[72] CBD is openly sold in head shops and health food stores in some states where such sales have not been explicitly legalized.[73][74]


“The brain has these receptors that respond to endocannabinoids, which are neurotransmitters that are naturally produced in the body and brain,” says Jerald Simmons, a neurologist at Houston’s Comprehensive Sleep Medicine Associates. “Some of the cannabinoids in the marijuana plant are very similar to the endocannabinoids in the brain, and they act on the same receptors.”

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As part of the Agriculture Improvement Act of 2018, or the 2018 Farm Bill, signed by Republican President Donald Trump, the Hemp Farming Act of 2018 removed hemp (with less than 0.3% THC) from Schedule I, the most restrictive classification of controlled substances that are considered highly prone to abuse and not to have any medicinal benefit. This move allowed for cultivation and distribution of hemp as a legal agricultural product. Under the Hemp Farming Act, hemp cultivation is no longer limited to state departments and universities. In addition, the act allows hemp farmers rights to water, crop insurance, and federal agricultural grants, as well as legal access to national banking. Hemp may also be transported across state lines.   
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Marijuana, also called pot, weed, ganja, mary jane, and a host of other nicknames, is made from the Cannabis plant, which has three species: Cannabis sativa; Cannabis indica and Cannabis ruderalis. The flowering plant, which can grow to 16 feet (5 meters) high, likely originated in the Central Asian steppe, near the Altai or Tian Shian Mountains, and was first cultivated in China and India, according to "Cannabis and Cannabinoids: Pharmacology, Toxicology and Therapeutic Potential," (Routledge, 2002).
Historically, hemp could legally be grown and cultivated for academic research purposes only. However, the legality of hemp growth has changed in the past year. In April 2018, Sen. Mitch McConnell of Kentucky introduced the Hemp Farming Act of 2018, a piece of legislation that proposed legalizing all hemp products at the federal level. The act was incorporated in the 2018 United States Farm Bill, which passed in both the House and Senate in December 2018. Per the farm bill, industrial hemp will be descheduled as a federally controlled substance. 

Jews living in Palestine in the 2nd century were familiar with the cultivation of hemp, as witnessed by a reference to it in the Mishna (Kil'ayim 2:5) as a variety of plant, along with Arum, that sometimes takes as many as three years to grow from a seedling. In late medieval Germany and Italy, hemp was employed in cooked dishes, as filling in pies and tortes, or boiled in a soup.[116] Hemp in later Europe was mainly cultivated for its fibers, and was used for ropes on many ships, including those of Christopher Columbus. The use of hemp as a cloth was centered largely in the countryside, with higher quality textiles being available in the towns.
The farm bill is a sprawling piece of legislation that sets U.S. government agricultural and food policy for the country and is renewed roughly every five years. This version of the bill places industrial hemp — which is defined as a cannabis plant with under 0.3% of tetrahydrocannabinol, or THC — under the supervision of the Agriculture Department and removes CBD from the purview of the Controlled Substances Act, which covers marijuana. The law also “explicitly” preserved the Food and Drug Administration’s authority to regulate products containing cannabis, or cannabis-derived compounds.

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