The Marinol patient monograph cautions that patients should not drive, operate machinery or engage in hazardous activities until accustomed to the drug’s effects (http://www.solvaypharmaceuticals-us.com/static/wma/pdf/1/3/1/9/Marinol5000124ERev52003.pdf). The Sativex product monograph in Canada (http://www.bayerhealth.ca/display.cfm?Object_ID=272&Article_ID=121&expandMenu_ID=53&prevSubItem=5_52) suggests that patients taking it should not drive automobiles. Given that THC is the most active component affecting such abilities, and the low serum levels produced in Sativex therapy (vide supra), it would be logical that that patients may be able to safely engage in such activities after early dose titration and according to individual circumstances, much as suggested for oral dronabinol. This is particularly the case in view of a report by an expert panel (Grotenhermen et al 2005) that comprehensively analyzed cannabinoids and driving. It suggested scientific standards such as roadside sobriety tests, and THC serum levels of 7–10 ng/mL or less, as reasonable approaches to determine relative impairment. No studies have demonstrated significant problems in relation to cannabis affecting driving skills at plasma levels below 5 ng/mL of THC. Prior studies document that 4 rapid oromucosal sprays of Sativex (greater than the average single dose employed in therapy) produced serum levels well below this threshold (Russo 2006b). Sativex is now well established as a cannabinoid agent with minimal psychotropic effect.
THC, an intoxicating and illegal substance, is responsible for causing marijuana users to get “high.” Unlike THC, CBD is non-psychoactive because it does not act on the same pathways as THC. Thus, it is impossible to get “high” by smoking or ingesting CBD or CBD oil extracted from industrial hemp plants, as they only have minuscule traces of THC (<0.3%).
Just read your article about CBD oil and checked the label on the oil I bought 9 months ago from a legal dispensary in Pendleton, Oregon. Across from the Subway. It lists herbs and supplements long before CBD oil and it is a derivative of Hemp oil. I paid $52 for one ounce (30 ml). I had not done any research prior to my purchase and relied on the folks at the marijuana shop to sell me a good product. Buyer beware is the best advice I got from this article. I have not achieved any pain relief from this product and use about 1 ml under my tongue with the dropper in the bottle. I intend to find a full spectrum CBD oil and I hope to notice a difference in pain relief. Thanks for the great information.
Tocopherols. Tocopherols are major antioxidants in human serum. Alpha- beta-, gamma- and delta-tocopherol represent the vitamin E group. These fat-soluble vitamins are essential for human nutrition, especially the alpha-form, which is commonly called vitamin E. About 80% of the tocopherols of hempseed oil is the alpha form. The vitamin E content of hempseed is comparatively high. Antioxidants in hempseed oil are believed to stabilize the highly polyunsaturated oil, tending to keep it from going rancid. Sterols in the seeds probably serve the same function, and like the tocopherols are also desirable from a human health viewpoint.
Fatty Acids. The quality of an oil or fat is most importantly determined by its fatty acid composition. Hemp is of high nutritional quality because it contains high amounts of unsaturated fatty acids, mostly oleic acid (C18:1, 10%–16%), linoleic acid (C18:2, 50%–60%), alpha-linolenic acid (C18:3, 20%–25%), and gamma-linolenic acid (C18:3, 2%–5%) (Fig. 37). Linoleic acid and alpha-linolenic acid are the only two fatty acids that must be ingested and are considered essential to human health (Callaway 1998). In contrast to shorter-chain and more saturated fatty acids, these essential fatty acids do not serve as energy sources, but as raw materials for cell structure and as precursors for biosynthesis for many of the body’s regulatory biochemicals. The essential fatty acids are available in other oils, particularly fish and flaxseed, but these tend to have unpleasant flavors compared to the mellow, slightly nutty flavor of hempseed oil. While the value of unsaturated fats is generally appreciated, it is much less well known that the North American diet is serious nutritionally unbalanced by an excess of linoleic over alpha-linonenic acid. In hempseed, linoleic and alpha-linolenic occur in a ratio of about 3:1, considered optimal in healthy human adipose tissue, and apparently unique among common plant oils (Deferne and Pate 1996). Gamma-linolenic acid or GLA is another significant component of hemp oil (1%–6%, depending on cultivar). GLA is a widely consumed supplement known to affect vital metabolic roles in humans, ranging from control of inflammation and vascular tone to initiation of contractions during childbirth. GLA has been found to alleviate psoriasis, atopic eczema, and mastalgia, and may also benefit cardiovascular, psychiatric, and immunological disorders. Ageing and pathology (diabetes, hypertension, etc.) may impair GLA metabolism, making supplementation desirable. As much as 15% of the human population may benefit from addition of GLA to their diet. At present, GLA is available in health food shops and pharmacies primarily as soft gelatin capsules of borage or evening primrose oil, but hemp is almost certainly a much more economic source. Although the content of GLA in the seeds is lower, hemp is far easier to cultivate and higher-yielding. It is important to note that hemp is the only current natural food source of GLA, i.e. not requiring the consumption of extracted dietary supplements. There are other fatty acids in small concentrations in hemp seed that have some dietary significance, including stearidonic acid (Callaway et al. 1996) and eicosenoic acid (Mölleken and Theimer 1997). Because of the extremely desirable fatty acid constitution of hemp oil, it is now being marketed as a dietary supplement in capsule form (Fig. 38).
^ World Health Organization.Constitution of the World Health Organization as adopted by the International Health Conference, New York, 19–22 June 1946; signed on 22 July 1946 by the representatives of 61 States (Official Records of the World Health Organization, no. 2, p. 100) and entered into force on 7 April 1948. In Grad, Frank P. (2002). "The Preamble of the Constitution of the World Health Organization". Bulletin of the World Health Organization. 80 (12): 982.
I have a brother in law who has been diagnosed with cataplexy and narcoplexy, where he starts quivering and slowly loses control of his body and goes into a sleep, which causes him to drop to the ground with mild seizures while he is out. He lives alone (59 years old), but has smoked cannabis since he (we) were teenagers. He still smokes, and is on medication twice a day for this condition, but if he misses those meds by even half an hour, he is at risk of these seizures. The sad part is, these seizures are usually brought on by the smallest emotional change, usually tension, excitement or, the worst thing, if something he finds funny and is the least bit tickled about and starts to laugh, this process will immediately begin. Does anyone know if this kind of condition is treatable with cbd oil’s or concentrates? As I said, he smokes weed, and often grows his own, but he does it for the high and relaxation advantage, since he is basically home-bound due to this condition ending his work career about 4 years ago. Thanks for any replies. I’d be overjoyed if I could tell him there’s a possible solution to the problem other than his prescriptions. Or even if it worked WITH his meds to keep from having to live such a sedentary life.

In states with medical cannabis laws, consumers should try to purchase cannabis from licensed suppliers who share their test results, which hopefully validate their products’ robust cannabinoid and terpenoid profiles. If you’re looking to purchase hemp through an online outlet, research your purchase beforehand to ensure that you aren’t being duped. 

A bit of online digging led me to realize that the active ingredient in Charlotte's Web Everyday Plus Hemp Oil, the product I'd been offered to test, was the chemical compound CBD, which stands for Cannabidiol. Unlike THC, the other crucial compound in hemp and marijuana plants, CBD does not produce the psychoactive effects that make you feel "high"; instead, it actually eases anxiety and makes you less likely to freak out.
Thapa, D., Toguri, J. T., Szczesniak, A. M., & Kelly, A. E. M. (2017, April 1). The non-psychoactive phytocannabinoid, cannabidiol (CBD), and the synthetic derivatives, HU308 and CBD-DMH, reduces hyperalgesia and inflammation in a mouse model of corneal injury [Abstract]. FASEB Journal. Retrieved from https://www.fasebj.org/doi/abs/10.1096/fasebj.31.1_supplement.811.7
In addition to the daily pain management program outlined above, many people find they still need a safe way to manage acute flare ups. Whether it’s caused by a recent injury, cold weather, or general aggravation  – we recommend vaporizing CBD isolate to combat these acute pain flare ups. The benefit of vaporizing or dabbing CBD isolate is that the relief can be felt almost instantaneously. CBD isolate is 99% pure CBD and provides a wave of relief that can be felt throughout the whole body.
Researchers in New Zealand have studied whether cannabis can be used to treat severe motor and vocal tics in those suffering from Tourette syndrome. The study concluded that subjects who took a controlled THC-CBD medicated spray showed marked improvement in the frequency and severity of motor and vocal tics post-treatment. Although the study is only a small clinical trial, it is one of the first to specifically analyze the effects of cannabis on Tourette syndrome.
Insomnia: The anxiety-alleviating and sleep-prolonging qualities of CBD oil make it a good option for many people with insomnia. Those who experience insomnia due to pain or discomfort may also find that using CBD oil alleviates their physical symptoms to a noticeable extent. CBD oil may also promote daytime wakefulness when taken in small amounts; people with insomnia can use it as a pick-me-up if they feel excessively tired due to lack of restful sleep.
Nabiximols (brand name Sativex) is a patented medicine containing CBD and THC in equal proportions. The drug was approved by Health Canada in 2005 for prescription to treat central neuropathic pain in multiple sclerosis, and in 2007 for cancer related pain.[39][40] In New Zealand Sativex® is approved for use as an add-on treatment for symptom improvement in patients with moderate to severe spasticity due to Multiple Sclerosis who have not responded adequately to other anti-spasticity medication and who demonstrate clinically significant improvement in spasticity related symptoms during an initial trial of therapy.[41]
In 2015, researchers conducted a comprehensive review to get at the heart of CBD and its intervention of addictive behaviors. These researchers gathered 14 studies, nine (9) of which involved animals, while the remaining five (5) involved humans, to find that CBD may indeed have therapeutic properties on opioid, cocaine, and psychostimulant addiction. Further, studies heavily suggest that CBD may also be beneficial in the treatment of marijuana and tobacco addiction. One reason that CBD may be effective as treatment for addictive disorders is its ability to ease the anxiety that leads people to crave drugs like heroin.
The term kief refers to the sticky, bulbous crystalline formations on the tip of a gland called a “trichome.” Trichomes are external resin glands packed with the chemicals that give marijuana its flavors and smells, called “terpenes.” They also contain high concentrations of cannabinoids. These chemicals which interact with our body to produce marijuana’s signature effects.
Cannabis, also referred to as marijuana, has been an integral part of human civilizations for millennia. Both as a medicine and as a recreational substance, cannabis is the most popular illicit drug in the world. Today, the legal landscape that has prohibited marijuana for much of the twentieth century is giving way to decriminalization and full legalization. Legal, commercial cannabis businesses are already making an enormous economic impact.
Cannabis use and psychotic symptoms and disorders are associated in the general population (see, for example, Degenhardt and Hall, 2001; Tien and Anthony, 1990) and in clinical samples of patients with schizophrenia (Mueser et al., 1992; Warner et al., 1994; Hambrecht and Hafner, 1996). The major contending hypotheses to explain the association have been: (i) that cannabis use precipitates schizophrenia in persons who are otherwise vulnerable; (ii) cannabis use is a form of self-medication for schizophrenia; and (iii) that the association arises from uncontrolled residual confounding by variables that predict an increased risk of cannabis use and of schizophrenia (Macleod et al., 2004).
Although marijuana smoke contains a number of carcinogens findings from a limited number of well-designed studies do not suggest an increased risk for the development of either lung or upper airway cancer from light or moderate use. However, the evidence is mixed when it comes to the carcinogenic risks of heavy, long-term marijuana users, according to this study.

Although THC is best known for its mind-altering euphoria, it too has important medical benefits. There’s some overlap in what CBD and THC can treat, but THC is particularly effective in relieving nausea, appetite loss, insomnia, among other symptoms. Many patients find that a balance of CBD and THC offers the best symptom relief as the two work together synergistically.


"The statute thus retains control over all varieties of the cannabis plant by virtue of including them under the term 'marijuana' and does not distinguish between low- and high-THC varieties. The language exempts from control the parts of mature plants—stalks, fiber, oil, cake, etc. — intended for industrial uses. Some have argued that the CSA definition exempts industrial hemp under its term exclusions for stalks, fiber, oil and cake, and seeds.44 DEA refutes this interpretation.45
^ Jump up to: a b Resstel LB, Tavares RF, Lisboa SF, Joca SR, Corrêa FM, Guimarães FS (January 2009). "5-HT1A receptors are involved in the cannabidiol-induced attenuation of behavioural and cardiovascular responses to acute restraint stress in rats". British Journal of Pharmacology. 156 (1): 181–8. doi:10.1111/j.1476-5381.2008.00046.x. PMC 2697769. PMID 19133999.
Sublingual CBD Oils – also known as CBD Tinctures or CBD Hemp Oil – are the most popular type of CBD products, because of their high bioavailability and rapid absorption. There are many other kinds of products as well, including CBD edibles, CBD topicals, and even CBD-infused Coffee. CBD products have gained immense popularity in health and wellness circles thanks to their natural support of our endocannabinoid system (ECS).
Fig. 2. Cannabis sativa. This superb composite plate by artist Elmer Smith, often reproduced at a very small scale and without explanation in marijuana books, is the best scientific illustration of the hemp plant ever prepared. 1. Flowering branch of male plant. 2. Flowering branch of female plant. 3. Seedling. 4. Leaflet. 5. Cluster of male flowers. 6. Female flower, enclosed by perigonal bract. 7. Mature fruit enclosed in perigonal bract. 8. Seed (achene), showing wide face. 9. Seed, showing narrow face. 10. Stalked secretory gland. 11. Top of sessile secretory gland. 12. Long section of cystolith hair (note calcium carbonate concretion at base). Reproduced with the permission of Harvard University, Cambridge, MA.
The ECS is responsible for setting the baseline activity levels of our immune system and nervous system, which then work to maintain our health. When the ECS falls out of whack, the systems that are regulated by it can begin to malfunction. CBD promotes the normal health and function of the endocannabinoid system, so it’s possible that CBD can help to alleviate the symptoms of conditions that are caused by dysfunction of the endocannabinoid system.
This is a huge, HUGE step for N.C. First of all farmers can FINALLY make money off land that has grown tobacco for generations. FINALLY doubter I finding out there are many uses for the plant. Perhaps one of the biggest things is the impact on the environment. Most products, if not all, are biodegradable. Also, a huge factor is that in the field of medicine. Will this lead to medical and/or recreational marijuana? Time will tell. As for me, I quit smoking it 20 years ago. I do, however, believe any and all forms of cannabis should and will be made legal. Legal, if for no other reason, so we can stop making people who smoke it into criminals, filling up our jails and prisons. This will free up police, etc.. to finding real criminals. Last, but defiantly not least, IMHO, there is the N.C. aspect. That being I thought we would never, EVER see this time in N.C. Even if it is just industrial hemp for now, it’s a start. Who knows, in the not too distant future, legislatures and law enforcement will become open minded enough to legalize all forms of cannabis, HOPEFULLY. With the youth of these times moving into the right fields, and of course us boomers weighing in, it won’t be too long. AMEN
Cannabis sativa is an annual wind-pollinated plant, normally dioecious and dimorphic, although sometimes monoecious (mostly in several modern European fiber cultivars). Figure 2 presents the basic morphology of the species. Some special hybrids, obtained by pollinating females of dioecious lines with pollen from monoecious plants, are predominantly female (so-called “all-female,” these generally also produce some hermaphrodites and occasional males). All-female lines are productive for some purposes (e.g. they are very uniform, and with very few males to take up space they can produce considerable grain), but the hybrid seed is expensive to produce. Staminate or “male” plants tend to be 10%–15% taller and are less robust than the pistillate or “female” (note the comparatively frail male in Fig. 3). So prolific is pollen production that an isolation distance of about 5 km is usually recommended for generating pure-bred foundation seed. A “perigonal bract” subtends each female flower, and grows to envelop the fruit. While small, secretory, resin-producing glands occur on the epidermis of most of the above-ground parts of the plant, the glands are very dense and productive on the perigonal bracts, which are accordingly of central interest in marijuana varieties. The root is a laterally branched taproot, generally 30–60 cm deep, up to 2.5 m in loose soils, very near the surface and more branched in wet soils. Extensive root systems are key to the ability of hemp crops to exploit deep supplies of nutrients and water. The stems are erect, furrowed, and usually branched, with a woody interior, and may be hollow in the internodes. Although the stem is often woody, the species is frequently referred to as a herb or forb. Plants vary enormously in height depending on genetic constitution and environment (Fig. 4), but are typically 1–5 m (heights of 12 m or more in cultivation have been claimed).
Dosage is important, because CBD can have side effects—the most common are tiredness, diarrhea, and changes in appetite and weight—so it’s best not to take more than you need. As CBD becomes more prevalent, says J. Michael Bostwick, M.D., a psychiatrist at Mayo Clinic in Rochester, MN, “I’m reasonably certain new kinds of side effects will emerge.”
Perhaps the most prevalent use for CBD is for pain management. The reality is that pain will affect everyone at some point in his or her life, and it’s comforting to know that there is a natural remedy that can help. The use of a natural remedy is especially important for those suffering from neuropathic pain and chronic pain – or pain that lasts for more than a few months. Chronic pain affects more than 3 million people in the United States every year – and the worst part? It can’t be cured. However, it can be treated and the irony is that in the United States, the most common medical treatments are nerve blocks, steroids, and narcotics (opioids) – many of which carry significant risk of side effects and addiction. Even over the counter non-steroidal anti-inflammatory drugs (NSAIDs) like Aspirin and ibuprofen are dangerous when used regularly – hospitalizing over 100,000 people each year and killing approximately 15,000. However, dangerous narcotics and NSAIDs are not your only option for pain relief! In addition to physical therapy and self-care, you can incorporate CBD into your treatment regimen for natural, plant-based pain relief. CBD is fundamentally different than most prescribed painkillers, as it’s not addictive, non-toxic, and has very minimal (if any) side effects. Click Here For CBD Health
Because hemp-derived CBD currently lacks labeling and purity standards that are required of cannabis products sold at legal dispensaries, it exists in a regulatory limbo that laws don’t yet address. In the meantime, the Los Angeles County Department of Public Health has announced that starting in July, putting CBD in food products will cost businesses points on their health inspections.
The nervous system’s endocannabinoid system is not well understood. But it’s thought to play a role in regulating pain, sleep, mood, memory, appetite, and other cognitive and physical processes. Because CBD is able to mimic the actions of some natural brain chemicals, its potential therapeutic benefits are wide-ranging but—at this point—nebulous. “We know that cannabidiol modulates the endocannabinoid system, but we don’t know how it works,” Szaflarski says. That said, there are theories.
Anecdotal evidence from patients is becoming increasingly widespread as well. Morgan Freeman suffers from pain and he was quoted saying, “I have fibromyalgia pain in my arm and the only thing that offers any relief is marijuana.” Whoopi Goldberg also uses cannabis to treat her daily pain from glaucoma and has even launched a line of medical cannabis products geared towards women suffering from menstrual pain.
While the science behind CBD oil assuaged many of my concerns, Charlotte Figi's inspiring story was the kicker. Figi, a 6-year-old girl diagnosed with a rare and resistant form of epilepsy known as Dravet syndrome, was actually placed on hospice care and given a "do not resuscitate" order when her parents, desperate and frustrated with pharmaceutical medication, considered medical marijuana. Charlotte is now 99% seizure-free since she began supplementing with Charlotte Web's CBD oil, which the brand named after Figi.
Lifestyle choices are contributing factors to poor health in many cases. These include smoking cigarettes, and can also include a poor diet, whether it is overeating or an overly constrictive diet. Inactivity can also contribute to health issues and also a lack of sleep, excessive alcohol consumption, and neglect of oral hygiene (Moffett2013).There are also genetic disorders that are inherited by the person and can vary in how much they affect the person and when they surface (Moffett, 2013).
Bruce Perlowin, CEO of Hemp, Inc, (OTC: HEMP), believes hemp legalization will drive disenfranchised farmers "back-to-the-land" now that they'll have a solid economic basis in industrial hemp to rely on. "Our strategy has been to partner with farmers across the country in states where hemp cultivation and manufacturing is legal to provide them with the infrastructure needed to make a profit off this incredible crop, and this bill will be an incredible boon for the American small family farm," Perlowin told me. "The health and wellness industries are in for a major overhaul with the massive research and development and exploration into CBD‘s, CBGs, CBN’s and 113 other cannabinoids as well as some 300 terpenes found in the industrial hemp plant."
"The 113th Congress considered various changes to U.S. policies regarding industrial hemp during the omnibus farm bill debate.42 The 2014 farm bill43 provides that certain 'institutions of higher education'44 and state departments of agriculture may grow industrial hemp, as part of an agricultural pilot program, if allowed under state laws where the institution or state department of agriculture is located. The farm bill also established a statutory definition of industrial hemp as 'the plant Cannabis sativa L. and any part of such plant, whether growing or not, with a delta-9 tetrahydrocannabinol concentration of not more than 0.3 percent on a dry weight basis.' The provision was included as part of the research title of the law. The provision did not include an effective date that would suggest any kind of program rollout, and there appears to be nothing in the conference report or bill language to suggest that the states might not be able to immediately initiate action on this provision."

"Many EU countries lifted their bans on hemp production in the 1990s and, until recently, also subsidized the production of 'flax and hemp' under the EU’s Common Agricultural Policy.32 EU hemp acreage was reported at about 26,000 acres in 2010, which was below previous years, when more than 50,000 acres of hemp were under production.33 Most EU production is of hurds, seeds, and fibers. Other non-EU European countries with reported hemp production include Russia, Ukraine, and Switzerland. Other countries with active hemp grower and/or consumer markets are Australia, New Zealand, India, Japan, Korea, Turkey, Egypt, Chile, and Thailand."
Medical marijuana can soothe nausea and increase appetite, quiet pain, soothe anxiety and even reduce epileptic seizures. Other research on the healing effects of cannabis is being examined. For example, research suggests that THC may be able to improve memory according to a 2016 study on mice. More than half of the United States has legalized marijuana for medical use.

Cannabis Ruderalis – Thought to be a cannabis species originating in central Asia, it flowers earlier, is much smaller, and can withstand much harsher climates than either Cannabis indica or Cannabis sativa. This species purportedly buds based on age rather than changes in length of daylight, known as auto-flowering. It’s used primarily for food production, such as hemp seeds and hemp seed oil.
C.S. Lewis said “badness is only spoiled goodness.” This may be an apt quote regarding public perception. It’s true that hemp’s scientific name is the same as that other Cannabis sativa, marijuana, but its constituents are different. The three cannabis plants have three different species: Sativa, used for industrial fibers, oils, food, drugs and medicine; Indica, to induce sleep; and Ruderalis, for food production. Hemp seeds contain high amounts of essential fatty acids – more than any fish and most fish oil supplements. The oil has linoleic acid, alpha-linolenic acid, and at least 20 amino acids. Altogether, hemp supplies innumerable health benefits. After decades of misunderstanding, scientists have again been tapping the amazing potential of this versatile plant.
Our Editor’s Pick is the tincture from CBDistillery. This tincture is available in five strengths ranging from 250mg to 5,000mg, which accommodates a wide range of THC preferences, as well as 15 and 30 milliliter containers. The tincture has a price-point that is slightly below average, making it a good option for value seekers. The tincture, which is non-flavored, routinely undergoes third-party testing to ensure safety and high quality; the testing results are available on CBDistillery’s product pages.
Preliminary work in Germany (noted in Karus and Leson 1994) suggested that hemp could be grown on soils contaminated with heavy metals, while the fiber remained virtually free of the metals. Kozlowski et al. (1995) observed that hemp grew very well on copper-contaminated soil in Poland (although seeds absorbed high levels of copper). Baraniecki (1997) found similar results. Mölleken et al. (1997) studied effects of high concentration of salts of copper, chromium, and zinc on hemp, and demonstrated that some hemp cultivars have potential application to growth in contaminated soils. It would seem unwise to grow hemp as an oilseed on contaminated soils, but such a habitat might be suitable for a fiber or biomass crop. The possibility of using hemp for bioremediation deserves additional study.
Some manufacturers ship CBD products nationally, an illegal action which the FDA has not enforced in 2018, with CBD remaining the subject of an FDA investigational new drug evaluation, and is not considered legal as a dietary supplement or food ingredient as of December 2018.[70][71] Federal illegality has made it difficult historically to conduct research on CBD.[72] CBD is openly sold in head shops and health food stores in some states where such sales have not been explicitly legalized.[73][74]
Male hemp plants flower much faster than females and do not produce nearly as much fiber. In stark contrast to marijuana fields, most female hemp fields include sporadically placed males. The male hemp plants release pollen for the female hemp plant to produce seeds that will either be used for future crops or sold as food. In marijuana fields, males are typically eliminated to ensure the maximum production of sensimilla flowers.
And without high-quality trials, experts don’t know how much is best for a given purpose. The staff at Roth’s dispensary told her, “Try some once or twice a day and see what happens.” (Half a dropper’s worth was a good amount for her.) One thing scientists feel confident about is that CBD is not dangerous. It won’t damage vital organs even at doses as high as 5,000 mg a day, Marcu says, and nobody has died from simply overdosing on a cannabis product.

Cannabis plants can be male, female, or hermaphrodite. The dried marijuana flowers that humans consume, however, come from the female plant. That’s because female plants produce large resin-secreting flowers that are rich in cannabinoids and free of seeds. Hence, female plants are the ones growers prefer, though of course, male marijuana plants are a requirement for pollination.


A 2015 review found that the use of high CBD-to-THC strains of cannabis showed significantly fewer positive symptoms such as delusions and hallucinations, better cognitive function and both lower risk for developing psychosis, as well as a later age of onset of the illness, compared to cannabis with low CBD-to-THC ratios.[279] A 2014 Cochrane review found that research was insufficient to determine the safety and efficacy to using cannabis to treat schizophrenia or psychosis.[280] As of 2017, the molecular mechanisms for the anti-inflammatory and possible pain relieving effects of cannabis are under preliminary research.[281]
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Sometimes, products that claim to contain CBD don’t have any at all when tested, Blessing says. More commonly, though, cookies and beverages simply contain far less than 300 milligrams of CBD, which is the minimum amount she says has been found effective in the preliminary science so far. Vybes, a brand of CBD-laced drinks, has 15 milligrams of the compound in each bottle. Feelz by Chloe, a line of CBD desserts from the vegan fast-casual chain By Chloe, has said in the past that each dessert contains only 2.5 milligrams of CBD a serving.
^ Jump up to: a b c d Boggs, Douglas L; Nguyen, Jacques D; Morgenson, Daralyn; Taffe, Michael A; Ranganathan, Mohini (6 September 2017). "Clinical and preclinical evidence for functional interactions of cannabidiol and Δ9-tetrahydrocannabinol". Neuropsychopharmacology. 43 (1): 142–154. doi:10.1038/npp.2017.209. ISSN 0893-133X. PMC 5719112. PMID 28875990. 

^ Jump up to: a b Batalla A, Bhattacharyya S, Yücel M, Fusar-Poli P, Crippa JA, Nogué S, Torrens M, Pujol J, Farré M, Martin-Santos R (2013). "Structural and functional imaging studies in chronic cannabis users: a systematic review of adolescent and adult findings". PLOS One. 8 (2): e55821. Bibcode:2013PLoSO...855821B. doi:10.1371/journal.pone.0055821. PMC 3563634. PMID 23390554. The most consistently reported brain alteration was reduced hippocampal volume which was shown to persist even after several months of abstinence in one study and also to be related to the amount of cannabis use Other frequently reported morphological brain alterations related to chronic cannabis use were reported in the amygdala the cerebellum and the frontal cortex...These findings may be interpreted as reflecting neuroadaptation, perhaps indicating the recruitment of additional regions as a compensatory mechanism to maintain normal cognitive performance in response to chronic cannabis exposure, particularly within the prefrontal cortex area.
There has been little high-quality research into the use of cannabidiol for epilepsy, and what there is is limited to refractory epilepsy in children.[16] While the results of using medical-grade cannabidiol in combination with conventional medication shows some promise, they did not lead to seizures being eliminated, and were associated with some minor adverse effects.[16]
In the Australian states of Tasmania, Victoria, Queensland, New South Wales, and most recently, South Australia, the state governments have issued licences to grow hemp for industrial use. The first to initiate modern research into the potential of cannabis was the state of Tasmania, which pioneered the licensing of hemp during the early 1990s. The state of Victoria was an early adopter in 1998, and has reissued the regulation in 2008.[75]
The edible seeds contain about 30 percent oil and are a source of protein, fibre, and magnesium. Shelled hemp seeds, sometimes called hemp hearts, are sold as a health food and may be eaten raw; they are commonly sprinkled on salads or blended with fruit smoothies. Hemp seed milk is used as an alternative to dairy milk in drinks and recipes. The oil obtained from hemp seed can be used to make paints, varnishes, soaps, and edible oil with a low smoke point. Historically, the seed’s chief commercial use has been for caged-bird feed.
In modern times, the Rastafari movement has embraced Cannabis as a sacrament.[125] Elders of the Ethiopian Zion Coptic Church, a religious movement founded in the United States in 1975 with no ties to either Ethiopia or the Coptic Church, consider Cannabis to be the Eucharist, claiming it as an oral tradition from Ethiopia dating back to the time of Christ.[126] Like the Rastafari, some modern Gnostic Christian sects have asserted that Cannabis is the Tree of Life.[127][128] Other organized religions founded in the 20th century that treat Cannabis as a sacrament are the THC Ministry,[129] Cantheism,[130] the Cannabis Assembly[131] and the Church of Cognizance. Rastafarians tend to be among the biggest consumers of modern Cannabis use.
CBD edibles are foods and beverages infused with CBD for oral consumption, and they are immensely popular thanks to their delicious taste as well as their soothing effects. From CBD fruit rolls to CBD-infused coffee, CBD edibles include a wide array of shapes, dosages, and mouthwatering flavors. CBD edibles offer an easy and discreet way to never forget your daily dose of CBD. Besides their fun and fruity taste and appearance, Green Roads CBD Edibles offer all the benefits of CBD in a convenient 30-day supply so you’ll never run out whether you need a short-term fix or long-term relief.
Despite some relatively tough talk from regulatory bodies, it can seem like they’re trying to close the barn door after the horse got out. CBD is already everywhere, and people are curious about it for reasons that seem to go far beyond trendiness, such as financial precariousness and health-care costs. “People are panicking and looking for things. They’re like, ‘What if I don’t have insurance because I get laid off? What can I replace my meds with?’” says Donahue, the Allure editor. CBD fits neatly with a growing distrust in technology and in the pharmaceutical industry, and America’s moderating view of cannabis means that many people see CBD as a safer alternative for anxiety or pain that’s worth trying.
The most valid claims to environmental friendliness of hemp are with respect to agricultural biocides (pesticides, fungicides, herbicides). Cannabis sativa is known to be exceptionally resistant to pests (Fig. 51), although, the degree of immunity to attacking organisms has been greatly exaggerated, with several insects and fungi specializing on hemp. Despite this, use of pesticides and fungicides on hemp is usually unnecessary, although introduction of hemp to regions should be expected to generate local problems. Cannabis sativa is also relatively resistant to weeds, and so usually requires relatively little herbicide. Fields intended for hemp use are still frequently normally cleared of weeds using herbicides, but so long as hemp is thickly seeded (as is always done when hemp is grown for fiber), the rapidly developing young plants normally shade out competing weeds.
^ Jump up to: a b Resstel LB, Tavares RF, Lisboa SF, Joca SR, Corrêa FM, Guimarães FS (January 2009). "5-HT1A receptors are involved in the cannabidiol-induced attenuation of behavioural and cardiovascular responses to acute restraint stress in rats". British Journal of Pharmacology. 156 (1): 181–8. doi:10.1111/j.1476-5381.2008.00046.x. PMC 2697769. PMID 19133999.
The use of Cannabis as a mind-altering drug has been documented by archaeological finds in prehistoric societies in Eurasia and Africa.[85] The oldest written record of cannabis usage is the Greek historian Herodotus's reference to the central Eurasian Scythians taking cannabis steam baths.[86] His (c. 440 BCE) Histories records, "The Scythians, as I said, take some of this hemp-seed [presumably, flowers], and, creeping under the felt coverings, throw it upon the red-hot stones; immediately it smokes, and gives out such a vapour as no Grecian vapour-bath can exceed; the Scyths, delighted, shout for joy."[87] Classical Greeks and Romans were using cannabis, while in the Middle East, use spread throughout the Islamic empire to North Africa. In 1545, cannabis spread to the western hemisphere where Spaniards imported it to Chile for its use as fiber. In North America, cannabis, in the form of hemp, was grown for use in rope, clothing and paper.[88][89][90][91]

"Skin dryness and itchiness, in particular, are very serious problems in atopic dermatitis, which often lead to additional complications, such as opportunistic infections. In any event, it seems that the reduction of atopic symptomology observed in this study is a direct result of ingested hempseed oil. These preliminary results confirm anecdotal observations of improved skin quality after ingesting modest amounts of hempseed oil on a daily basis over a relatively short period of time."
Because of its high THC-content, in most parts of the world, including the US, Marijuana is illegal. Seeing the massive economical and medicinal benefits that Marijuana can provide, some countries and states in the US have legalized Marijuana. As the political landscape changes, hopefully more will follow, but as of now, Marijuana is generally illegal.
The use of Cannabis for seed oil (Fig. 36) began at least 3 millennia ago. Hempseed oil is a drying oil, formerly used in paints and varnishes and in the manufacture of soap. Present cultivation of oilseed hemp is not competitive with linseed for production of oil for manufacturing, or to sunflower and canola for edible vegetable oil. However, as noted below, there are remarkable dietary advantages to hempseed oil, which accordingly has good potential for penetrating the salad oil market, and for use in a very wide variety of food products. There is also good potential for hemp oil in cosmetics and skin-care products.
Nabilone (Cesamet) (Figure 1), is a synthetic dimethylheptyl analogue of THC (British Medical Association 1997) that displays greater potency and prolonged half-life. Serum levels peak in 1–4 hours (Lemberger et al 1982). It was also primarily developed as an anti-emetic in chemotherapy, and was recently re-approved for this indication in the USA. Prior case reports have noted analgesic effects in case reports in neuropathic pain (Notcutt et al 1997) and other pain disorders (Berlach et al 2006). Sedation and dysphoria were prominent sequelae. An RCT of nabilone in 41 post-operative subjects actually documented exacerbation of pain scores after thrice daily dosing (Beaulieu 2006) (Table 1). An abstract of a study of 82 cancer patients on nabilone claimed improvement in pain levels after varying periods of follow-up compared to patients treated without this agent (Maida 2007). However, 17 subjects dropped out, and the study was neither randomized nor controlled, and therefore is not included in Table 1.
Selection for fiber has resulted in strains that have much more bark fiber tissues and much less woody core than encountered in narcotic strains, oilseed strains, and wild plants (Fig. 12). In non-fiber strains of Cannabis, bark can be less than one quarter of the stem tissues (i.e. more than three quarters can be woody core). By contrast, in fiber strains half of the stem tissues can be bark, and more than half of this can be the desirable long primary fibers (de Meijer 1995). Non-fiber strains rarely have as much as 15% fiber in the bark.
Moreover, a patient survey conducted by Project CBD, declared that “…cannabis appears to be an effective pain management tool with few negative side effects.” The study went on to say that a “…significant decrease in opiate usage among elderly patients while taking medical cannabis [was observed during trial].” In short, it has been portrayed clearly numerous times through valid and well-publicized clinical studies that cannabis is a practical option in terms of efficient pain management.
Selective breeding of cannabis plants has expanded and diversified as commercial and therapeutic markets develop. Some growers in the U.S. succeeded in lowering the proportion of CBD-to-THC to accommodate customers who preferred varietals that were more mind-altering due to the higher THC and lower CBD content.[57] Hemp is classified as any part of the cannabis plant containing (depending on the jurisdiction) no more than 0.2% to 1.0% THC in dry weight form (not liquid or extracted form).[58][unreliable source?]

Cannabis has psychoactive and physiological effects when consumed.[45] The immediate desired effects from consuming cannabis include relaxation and euphoria (the "high" or "stoned" feeling), a general alteration of conscious perception, increased awareness of sensation, increased libido[46] and distortions in the perception of time and space. At higher doses, effects can include altered body image, auditory and/or visual illusions, pseudohallucinations and ataxia from selective impairment of polysynaptic reflexes. In some cases, cannabis can lead to dissociative states such as depersonalization[47][48] and derealization.[49]


"Approximately 30 countries in Europe, Asia, and North and South America currently permit farmers to grow hemp. Some of these countries never outlawed production, while some countries banned production for certain periods in the past. China is among the largest producing and exporting countries of hemp textiles and related products, as well as a major supplier of these products to the United States. The European Union (EU) has an active hemp market, with production in most member nations. Production is centered in France, the United Kingdom, Romania, and Hungary.30
Marijuana or marihuana (herbal cannabis),[167] consists of the dried flowers and subtending leaves and stems of the female Cannabis plant.[168][169][170][171] This is the most widely consumed form,[171] containing 3% to 20% THC,[172] with reports of up-to 33% THC.[173] This is the stock material from which all other preparations are derived. Although herbal cannabis and industrial hemp derive from the same species and contain the psychoactive component (THC), they are distinct strains with unique biochemical compositions and uses. Hemp has lower concentrations of THC and higher concentrations of CBD, which decreases the psychoactive effects[174][175]
Donna Gregory Burch was diagnosed with fibromyalgia in 2014 after several years of unexplained pain, fatigue and other symptoms. She was later diagnosed with chronic Lyme disease. Donna covers news, treatments, research and practical tips for living better with fibromyalgia and Lyme on her blog, FedUpwithFatigue.com. You can also find her on Facebook and Twitter. Donna is an award-winning journalist whose work has appeared online and in newspapers and magazines throughout Virginia, Delaware and Pennsylvania. She lives in Delaware with her husband and their many fur babies.
Cannabinoids may offer significant “side benefits” beyond analgesia. These include anti-emetic effects, well established with THC, but additionally demonstrated for CBD (Pertwee 2005), the ability of THC and CBD to produce apoptosis in malignant cells and inhibit cancer-induced angiogenesis (Kogan 2005; Ligresti et al 2006), as well as the neuroprotective antioxidant properties of the two substances (Hampson et al 1998), and improvements in symptomatic insomnia (Russo et al 2007).
The earliest recorded uses date from the 3rd millennium BC.[32] Since the early 20th century, cannabis has been subject to legal restrictions. The possession, use, and sale of cannabis is illegal in most countries of the world.[33][34] Medical cannabis refers to the physician-recommended use of cannabis, which takes place in Canada, Belgium, Australia, the Netherlands, Germany, Spain, and 33 U.S. states.[35][36] In September 2018, cannabis was legalized in South Africa[37] while Canada legalized recreational use of cannabis in October 2018.[38]
In 2015, The Hebrew University of Israel published a study that documented the potency of single-molecule CBD extract versus the potency of whole-plant CBD-rich extract. It found that extract taken from whole plant CBD-rich cannabis is therapeutically superior to single-molecule extract. The scientists behind this study noticed that science had been utilizing pure, single-molecule CBD, which resulted in a bell-shaped dose-response curve. This means that CBD’s efficacy plummets at very high and very low doses.

Short-term use of the drug impairs thinking and coordination. In long-term studies, teens who smoke marijuana have lower IQs later on, as well as structural differences in their brains, though scientists debate whether this is an effect of the drug or a result of habitual pot smokers seeking out less intellectually stimulating pursuits. A 2016 study on almost 300 students by the University of Montreal published in the journal Development and Psychopathology found that teens who start smoking around age 14 do worse on some cognitive tests by age 20 than non-smokers. They also have a higher school dropout rate. If they wait until age 17 to start, though, the smokers do not seem to have the same impairments, according to the study. 
Hemp stalk is baled for transportation and long-term storage using traditional farming balers. Large round balers are best for hemp because they allow for more thorough drying as they don’t pack the hemp as tightly as square balers. Hemp should be stored in a dry environment in conditions intended to reduce as much absorbable air moisture as possible. It’s also important to check for wet patches during baling to further avoid mold.
A 2015 review found that the use of high CBD-to-THC strains of cannabis showed significantly fewer positive symptoms such as delusions and hallucinations, better cognitive function and both lower risk for developing psychosis, as well as a later age of onset of the illness, compared to cannabis with low CBD-to-THC ratios.[279] A 2014 Cochrane review found that research was insufficient to determine the safety and efficacy to using cannabis to treat schizophrenia or psychosis.[280] As of 2017, the molecular mechanisms for the anti-inflammatory and possible pain relieving effects of cannabis are under preliminary research.[281]
Cannabis, (genus Cannabis), plant belonging to the family Cannabaceae of the nettle order (Urticales). By some classifications, the genus Cannabis comprises a single species, hemp (Cannabis sativa), a stout, aromatic, erect annual herb that originated in Central Asia and is now cultivated worldwide, including in Europe, southern Asia, the Middle East, India, Africa, and the Americas. A tall canelike variety is raised for the production of hemp fibre, while the female plant of a short branchier variety is prized as the more abundant source of the psychoactive substance tetrahydrocannabinol (THC), the active ingredient of marijuana.
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I use this for my anxiety and for my arthritis. The topical works great for my chronic neck pain. The best way to go is to get your own raw, tested material and use it in whatever form you like. It’s quite easy to make your own extract. This has worked better for me, rather than relying on a purchased, untested product – where some seem to work and others are a waste. But even with those that work, of course the cost is ridiculous and not affordable, thanks to all these corporate-pleasing laws in place, not there for the people – don’t delude yourselves.
Like everything else in the U.S it is buyer beware. I was told that the 30 dollar a bottle Hemp Oil, would not work becasue I was “Skeptical.” I had asked exactly these questions at a Dispensary. The CBD Craze is mostly hype. It does little or nothing for pain, or anything else. The only thing I have seen is that when it is derived from marijuana in the for of a Salve with the a small amount of THC in it, it might help with arthritis topically.
There’s no definite amount that’s appropriate for everyone, but the ratio of CBD to THC will indicate how psychoactive the product is and if it’s legal in your state. The more CBD compared with THC, the less of a high, and vice versa. “Managing psychoactivity is key to successful cannabis therapy,” says Lee. “Amounts should be made clear on the label and lab-certified so people know what’s helping them and what’s not.” 

The maintenance and promotion of health is achieved through different combination of physical, mental, and social well-being, together sometimes referred to as the "health triangle."[24][25] The WHO's 1986 Ottawa Charter for Health Promotion further stated that health is not just a state, but also "a resource for everyday life, not the objective of living. Health is a positive concept emphasizing social and personal resources, as well as physical capacities."[26]
Hi Diane, how did you go on with the CBD oil please. If it worked how long before you saw any results. I'm scared of flaring everything. Nerve damage across buttocks from a surgeon who found the nerve stuck to the bulge during a laminectomy operation and prised it off. I haven't sat for 5 years and getting worse. A muscle in my buttock is now throbbing constantly and causing pain to the muscle above. I've only started taking it today but the muscle pain is still as painful. Does it take a while for it to work. Only started on low dose to see what happens. Thank you Lyn
According to the U.S. Department of Health and Human Services, 116 people died every-day from opioid-related drug overdoses in 2016. Forty percent of these deaths involved a prescription opioid and in 2017, the government declared the opioid crisis a public health emergency. Opioids are typically prescribed by health care providers as a way to manage and treat pain. But what if there was a better solution?
There are lots of reasons to invest in hardy Doc Marten boots, but the process of actually breaking them in? Extremely painful. Last December, I found myself hobbling back to my apartment with new-Doc battle wounds — a cut on my ankle and swollen, blistering feet. On a lark, I used the supposedly miraculous CBD lotion from Lord Jones. I can’t believe I’m saying this, but it worked.
At least 38 states considered legislation related to industrial hemp in 2018. These bills ranged from clarifying existing laws to establishing new licensing requirements and programs. At least six states – Alaska, Arizona, Kansas, Missouri, New Jersey and Oklahoma – enacted legislation in 2018 establishing hemp research and industrial hemp pilot programs. Georgia created the House Study Committee on Industrial Hemp Production. States, already allowing for industrial hemp programs, continued to consider policies related to licensure, funding, seed certification, and other issues. For example, Tennessee amended its Commercial Feed Law to include hemp. 
Canada is specialized on oilseed production and processing, so that hemp oil and grain are much more suitable than fiber. Because of the extensive development of oilseeds in Canada, there is extensive capacity to produce high-quality cold-pressed hemp oil. Canada in the last 5 years has made great advances in the growing, harvesting, and processing of hempseed, and indeed has moved ahead of the EU in the development of raw materials and products for the natural foods, nutraceuticals, and cosmetics industries. In the EU, a yield of 1 t/ha is considered good. In Canada, extraordinary yields of 1.5 t/ha have been realized, at least locally, although in the initial years of hempseed development in Canada yields were often less than 500 kg/ha. In 1999, the year of largest Canadian hemp acreage, yields averaged 900 kg/ha. (Ideally, hemp seed yield should be based on air dry weight—with about 12% moisture. Hemp yields are sometime uncertain, and could be exaggerated by as much as 50% when moist weights are reported.)
Topicals represent a newer emerging market in medical marijuana products geared toward health and beauty. Cannabinoids can be absorbed through the skin for certain therapeutic benefits without any psychoactivity. Additionally, the essential oils in hemp and cannabis provide many benefits for skin health. From moisturizers to shampoos and deodorants, medical cannabis products continue to diversify.

For those wondering does hemp CBD oil for pain relief really work? There have been many studies that have demonstrated that using CBD is one of the most effective means of helping people who are suffering from chronic forms of pain. For those who have had injuries or ailments that have caused debilitating pain even for a short period of time, there is truly nothing they want more than to see this pain reduced, if not removed all together. This has been of the great benefits of cannabidiol oil.
Donald Abrams was a member of the committee that reviewed the evidence that went into producing the report, and he said that the studies they reviewed overwhelmingly used pharmaceutically available preparations that contain THC, including dronabinol, nabilone and the whole-plant extract spray nabiximols, which contains equal parts CBD and THC. It’s impossible to know whether the benefits of cannabis can also be obtained from CBD alone, Abrams said, because CBD is just one of 400 chemicals present in the plant. So far, CBD in isolation has been studied in only a handful of randomized, placebo-controlled trials (considered the gold standard of evidence in medical research), and the evidence remains sparse.

"The term ‘“marihuana” means all parts of the plant Cannabis sativa L., whether growing or not; the seeds thereof; the resin extracted from any part of such plant; and every compound, manufacture, salt, derivative, mixture, or preparation of such plant, its seeds or resin. Such term does not include the mature stalks of such plant, fiber produced from such stalks, oil or cake made from the seeds of such plant, any other compound, manufacture, salt, derivative, mixture, or preparation of such mature stalks (except the resin extracted therefrom), fiber, oil, or cake, or the sterilized seed of such plant which is incapable of germination.140
"Hemp fields, in fact, could be a deterrent to marijuana growers. A strong case can be made that the best way to reduce the THC level of marijuana grown outdoors would be to grow industrial hemp near it. An experiment in Russia found that hemp pollen could travel 12 kilometers. This would mean that a hemp field would create a zone with a 12-kilometer radius within which no marijuana grower would want to establish a crop.
To decide between these hypotheses, we need evidence that cannabis use preceded the psychosis; that plausible alternative explanations based on confounding can be excluded (Hall, 1987). The best evidence for answering these questions comes from longitudinal population-based studies that have assessed cannabis use before the onset of psychotic symptoms, followed the cohort over a substantial period and used statistical methods to assess the contribution of a variety of factors other than cannabis use that may explain the relationship (Macleod et al., 2004).
American Shaman CBD oil capsules is potent and speedy in relieving pain. It is among the strongest CBD products on the market due to the high concentrations of CBD. In terms of concentration, it is one of the front runners. The manufacturer is not new at all, so it does not belong to this modern trend of CBD , but its products dominate the market for years. Overtime, it has developed a solid reputation based on quality.
"No data are available on imports of hemp seed and oil into the United States, but data do exist on hemp fiber, yarn, and fabrics. Imports of raw hemp fiber have increased dramatically in the last few years, rising from less than 500 pounds in 1994 to over 1.5 million pounds for the first 9 months of 1999. Yarn imports also have risen substantially, peaking at slightly less than 625,000 pounds in 1997. The switch from yarn to raw fiber in the last 2 years probably reflects the development of U.S. spinning capacity. At least two companies are now spinning hemp yarn from imported fibers. Imports of hemp fabric have more than doubled from over 222,000 pounds in 1995 to about 523,000 pounds in 1998.
Some users speculate about appropriate dosages or methods of application—including whether or not a small amount of THC boosts CBD’s effects, or whether different methods of administration lead to quicker or more significant effects. Some CBD producers also claim that it has a cumulative effect, and so needs to be used regularly to produce a benefit. But Grant says it’s tough to say at this point exactly how people should (or shouldn’t) be using CBD.

The etymology is uncertain but there appears to be no common Proto-Indo-European source for the various forms of the word; the Greek term kánnabis is the oldest attested form, which may have been borrowed from an earlier Scythian or Thracian word.[9][10] Then it appears to have been borrowed into Latin, and separately into Slavic and from there into Baltic, Finnish, and Germanic languages.[11] Following Grimm's law, the "k" would have changed to "h" with the first Germanic sound shift,[9][12] after which it may have been adapted into the Old English form, hænep. However, this theory assumes that hemp was not widely spread among different societies until after it was already being used as a psychoactive drug, which Adams and Mallory (1997) believe to be unlikely based on archaeological evidence.[9] Barber (1991) however, argued that the spread of the name "kannabis" was due to its historically more recent drug use, starting from the south, around Iran, whereas non-THC varieties of hemp are older and prehistoric.[11] Another possible source of origin is Assyrian qunnabu, which was the name for a source of oil, fiber, and medicine in the 1st millennium BC.[11]
One of the most experienced practitioners in this field is Los Angeles physician Bonni Goldstein, who has used the compound to treat dozens of children with intractable epilepsy. She says about half of these patients have seen a significant drop in the number of seizures. “Used in the right way, with the right patient, CBD is extremely powerful,” she says.
A study by Henquet and colleagues (2004) substantially replicated both the Swedish and Dutch studies in a 4-year follow-up of a cohort of 2437 adolescents and young adults between 1995 and 1999 in Munich. They found a dose–response relationship between self-reported cannabis use at baseline and the likelihood of reporting psychotic symptoms. As in the Dutch cohort, young people who reported psychotic symptoms at baseline were much more likely to experience psychotic symptoms at follow-up if they used cannabis than were cannabis-using peers without such a history.

Right now, due to arcane laws that are about to change around the world, and strange licensing procedures, cannabis is a supply issue, but that will all change over time.  Cannabis is a plant that can grow in 12 weeks, 16 weeks for some Indica strains.  There will never be a shortage or issue with getting cannabis when it is a plant that can be produced anywhere in the world, in large batches, every 12 weeks.
ECS is made up of endocannabinoids and the receptors associated with them. These receptors are literally found from head to toe, and are in such places as the glands, organs, and the brain. While receptors and endocannabinoids are located in all parts of the body, they have different functions depending upon where they are located, with the primary role being to regulate what is referred to as homeostasis or the regulation of the body so that it is at equilibrium.
The authors compared this patient's CT scan with one from a cigarette smoker. The second scan illustrated a strikingly different pattern of emphysema, with smaller panacinar bullae in a uniformly distributed centrilobular pattern. An explanation of the differences in lung findings due to cannabis and cigarettes would take into account a number of variables. Cannabis smoking requires longer inhalation and breath-holding time. Inhaled cannabis through a bong is at a higher temperature. A cannabis joint, which lacks a filter, also has a greater delivery of the drug.
If you haven’t been bombarded with CBD marketing or raves about it from friends, get ready. This extract—which comes from either marijuana or its industrial cousin, hemp—is popping up everywhere. There are CBD capsules, tinctures, and liquids for vaping plus CBD-infused lotions, beauty products, snacks, coffee, and even vaginal suppositories. Already some 1,000 brands of CBD products are available in stores—and online in states that don’t have lenient cannabis laws. This is a tiny fraction of what’s to come: The CBD market is poised to exceed $1 billion by 2020, per the Chicago-based research firm Brightfield Group.
Public health has been described as "the science and art of preventing disease, prolonging life and promoting health through the organized efforts and informed choices of society, organizations, public and private, communities and individuals."[52] It is concerned with threats to the overall health of a community based on population health analysis. The population in question can be as small as a handful of people or as large as all the inhabitants of several continents (for instance, in the case of a pandemic). Public health has many sub-fields, but typically includes the interdisciplinary categories of epidemiology, biostatistics and health services. Environmental health, community health, behavioral health, and occupational health are also important areas of public health.
The world-leading producer of hemp is China, which produces more than 70% of the world output. France ranks second with about a quarter of the world production. Smaller production occurs in the rest of Europe, Chile, and North Korea. Over 30 countries produce industrial hemp, including Australia, Austria, Canada, Chile, China, Denmark, Egypt, Finland, Germany, Greece,[68] Hungary, India, Italy, Japan, Korea, Netherlands, New Zealand, Poland, Portugal, Romania, Russia, Slovenia, Spain, Sweden, Switzerland, Thailand, Turkey, the United Kingdom and Ukraine.[69][70]
Sometimes, products that claim to contain CBD don’t have any at all when tested, Blessing says. More commonly, though, cookies and beverages simply contain far less than 300 milligrams of CBD, which is the minimum amount she says has been found effective in the preliminary science so far. Vybes, a brand of CBD-laced drinks, has 15 milligrams of the compound in each bottle. Feelz by Chloe, a line of CBD desserts from the vegan fast-casual chain By Chloe, has said in the past that each dessert contains only 2.5 milligrams of CBD a serving.
The 2014 Farm Bill[75] legalized the sale of "non-viable hemp material" grown within states participating in the Hemp Pilot Program.[76] This legislation defined hemp as cannabis containing less than 0.3% of THC delta-9, grown within the regulatory framework of the Hemp Pilot Program.[77] The 2018 Farm Bill allowed for interstate commerce of hemp derived products, though these products still fall under the purview of the FDA.[78][79]
CBD was first discovered in 1940 by Roger Adams, a prominent organic chemist at the University of Illinois. Shortly thereafter, other scientists began testing isolated cannabinoids on lab animals; notably, Walter S. Loewe ran trials on mice and rabbits with the cannabinoids THC, CBD and CBN. He found that CBD produced no observable effects in the animals’ behavior while THC caused, what he called, a “central excitant action” in rabbits. Despite science’s movement forward, scientists were completely unaware of the cannabinoids’ chemical structure, so no one could tell which specific compound resulted in which effect.
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