AC/DC: A Sativa-dominant phenotype of Cannatonic, this cultivar boasts one of the highest ratios of CBD to THC, clocking in at 20:1. AC/DC is claimed to help reduce pain, anxiety, depression and migraines while reducing symptoms in patients with epilepsy, some forms of cancer, and multiple sclerosis. This cultivar’s pinene-rich terpene profile offers potent clear-headed pain relief.

Researchers in New Zealand have studied whether cannabis can be used to treat severe motor and vocal tics in those suffering from Tourette syndrome. The study concluded that subjects who took a controlled THC-CBD medicated spray showed marked improvement in the frequency and severity of motor and vocal tics post-treatment. Although the study is only a small clinical trial, it is one of the first to specifically analyze the effects of cannabis on Tourette syndrome.
Donald Abrams was a member of the committee that reviewed the evidence that went into producing the report, and he said that the studies they reviewed overwhelmingly used pharmaceutically available preparations that contain THC, including dronabinol, nabilone and the whole-plant extract spray nabiximols, which contains equal parts CBD and THC. It’s impossible to know whether the benefits of cannabis can also be obtained from CBD alone, Abrams said, because CBD is just one of 400 chemicals present in the plant. So far, CBD in isolation has been studied in only a handful of randomized, placebo-controlled trials (considered the gold standard of evidence in medical research), and the evidence remains sparse.

Many governments view occupational health as a social challenge and have formed public organizations to ensure the health and safety of workers. Examples of these include the British Health and Safety Executive and in the United States, the National Institute for Occupational Safety and Health, which conducts research on occupational health and safety, and the Occupational Safety and Health Administration, which handles regulation and policy relating to worker safety and health.[63][64][65]
Hemp has at times in the past been grown simply for its ornamental value. The short, strongly-branched cultivar ‘Panorama’ (Fig. 43) bred by Iván Bósca, the dean of the world’s living hemp breeders, was commercialized in Hungary in the 1980s, and has been said to be the only ornamental hemp cultivar available. It has had limited success, of course, because there are very few circumstances that permit private gardeners can grow Cannabis as an ornamental today. By contrast, beautiful ornamental cultivars of opium poppy are widely cultivated in home gardens across North America, despite their absolute illegality and the potentially draconian penalties that could be imposed. Doubtless in the unlikely event that it became possible, many would grow hemp as an ornamental.

Since then, many different types of sex determination systems have been discovered, particularly in plants.[15] Dioecy is relatively uncommon in the plant kingdom, and a very low percentage of dioecious plant species have been determined to use the XY system. In most cases where the XY system is found it is believed to have evolved recently and independently.[31]

^ Klein C, Karanges E, Spiro A, Wong A, Spencer J, Huynh T, Gunasekaran N, Karl T, Long LE, Huang XF, Liu K, Arnold JC, McGregor IS (November 2011). "Cannabidiol potentiates Δ⁹-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats". Psychopharmacology. 218 (2): 443–457. doi:10.1007/s00213-011-2342-0. PMID 21667074.

A wide variety of hemp clothing, footwear, and food products are now available in North America. Some American manufacturers and distributors have chosen to exploit the association of hemp products with marijuana in their advertising. Such marketing is unfortunate, sending the message that some in the industry are indifferent to the negative image that this generates in the minds of much of the potential consuming public. Admittedly, such advertising works. But marketing based on the healthful and tasteful properties of hemp food products, the durable nature of hemp textiles, and the environmental advantages of the crop has proven to be widely acceptable, and is likely to promote the long term development of hemp industries.

The gateway effect may appear due to social factors involved in using any illegal drug. Because of the illegal status of cannabis, its consumers are likely to find themselves in situations allowing them to acquaint with individuals using or selling other illegal drugs.[268][269] Utilizing this argument some studies have shown that alcohol and tobacco may additionally be regarded as gateway drugs;[270] however, a more parsimonious explanation could be that cannabis is simply more readily available (and at an earlier age) than illegal hard drugs. In turn alcohol and tobacco are easier to obtain at an earlier point than is cannabis (though the reverse may be true in some areas), thus leading to the "gateway sequence" in those individuals since they are most likely to experiment with any drug offered.[261]

Thapa, D., Toguri, J. T., Szczesniak, A. M., & Kelly, A. E. M. (2017, April 1). The non-psychoactive phytocannabinoid, cannabidiol (CBD), and the synthetic derivatives, HU308 and CBD-DMH, reduces hyperalgesia and inflammation in a mouse model of corneal injury [Abstract]. FASEB Journal. Retrieved from
Marijuana is the most popular illicit drug in the world, for no reason other than the fact that it produces a psychoactive chemical called tetrahydrocannabinol. Still, recreational marijuana use, which involves pursuing the euphoric sensations produced by cannabis consumption, is steadily becoming more and more legal, both in the United States and abroad.
One area where CBD is clearly helpful: the treatment of seizures associated with one form of epilepsy. A 2017 New England Journal of Medicine study found ingesting oral CBD dramatically cut down most patients’ seizure frequency—a finding that prompted the FDA to support the approval of one CBD drug for use in the treatment of some epilepsy patients.
Cannabis has psychoactive and physiological effects when consumed.[45] The immediate desired effects from consuming cannabis include relaxation and euphoria (the "high" or "stoned" feeling), a general alteration of conscious perception, increased awareness of sensation, increased libido[46] and distortions in the perception of time and space. At higher doses, effects can include altered body image, auditory and/or visual illusions, pseudohallucinations and ataxia from selective impairment of polysynaptic reflexes. In some cases, cannabis can lead to dissociative states such as depersonalization[47][48] and derealization.[49]

Still, as the saying goes, absence of evidence isn’t necessarily evidence of absence, and there’s a reason we don’t have a ton of solid research on CBDs yet — “to study it, we need a good source, ” said Ziva Cooper, who is an associate professor at Columbia University and was on the National Academies committee. CBD is hard to get because it’s still technically a Schedule I drug, which limits its availability, Cooper said.
Cement (Concrete) and Plaster. Utilizing the ancient technique of reinforcing clay with straw to produce reinforced bricks for constructing domiciles, plant fibers have found a number of comparable uses in modern times. Hemp fibers added to concrete increase tensile strength while reducing shrinkage and cracking. Whole houses have been made based on hemp fiber (Fig. 24, 25). In North America, such usage has only reached the level of a cottage industry. Fiber-reinforced cement boards and fiber-reinforced plaster are other occasionally produced experimental products. Hemp fibers are produced at much more cost than wood chips and straw from many other crops, so high-end applications requiring high strength seem most appropriate.
There is reasonable evidence from prospective epidemiological studies which suggests that cannabis use can precipitate schizophrenia in persons who are vulnerable because of a personal or family history of schizophrenia. There is also evidence that a genetic vulnerability to psychosis increases the risk that cannabis users will develop psychosis (McGuire et al., 1995; Arseneault et al., 2002; Verdoux et al., 2002). A casual relationship also has biological plausibility in that the cannabinoid and dopaminergic neurotransmitter systems interact in animals. D'Souza and colleagues (1999) have shown in a provocation study that THC produces a dose-dependent increase in psychotic symptoms under double-blind placebo conditions; and Caspi and colleagues (2005) have shown an interaction between specific alleles of the COMT allele and psychotogenic effects of cannabis. If these results can be replicated and extended, they will increase the likelihood that cannabis can be a contributory cause of psychosis in vulnerable individuals.
Receptra offers their products in two separate lines. One is the Active Lifestyle range, which provides lower concentrations for daily use, and another is Health and Wellness, which is for far more intense use. It is incredibly difficult for me to manage my back pain with a low concentration of CBD usually, so, I went with the 3000 mg concentration available in their Health and Wellness line.    

In the United States, non-FDA approved CBD products are classified as Schedule I drugs under the Controlled Substances Act.[62] This means that production, distribution, and possession of non-FDA approved CBD products is illegal under federal law. In addition, in 2016 the Drug Enforcement Administration added "marijuana extracts" to the list of Schedule I drugs, which it defined as "an extract containing one or more cannabinoids that has been derived from any plant of the genus Cannabis, other than the separated resin (whether crude or purified) obtained from the plant."[63] Previously, CBD had simply been considered "marijuana", which is a Schedule I drug.[62][64]
The list includes marijuana (undifferentiated by strain) and heroin. (While the federal government oversees marijuana research, marijuana use is regulated, in part, by state laws.) As a result, scientists who study the compound must follow a host of restrictive rules. Last year, responding to a request from several governors to change marijuana’s designation, the Drug Enforcement Administration announced that all cannabis would remain a Schedule 1 drug.
Cannabis was known to the ancient Assyrians, who discovered its psychoactive properties through the Iranians.[197] Using it in some religious ceremonies, they called it qunubu (meaning "way to produce smoke"), a probable origin of the modern word "cannabis".[198] The Iranians also introduced cannabis to the Scythians, Thracians and Dacians, whose shamans (the kapnobatai—"those who walk on smoke/clouds") burned cannabis flowers to induce trance.[199] The plant was used in China before 2800 BC, and found therapeutic use in India by 1000 BC, where it was used in food and drink, including bhang.[200][201]
Cannabis is first referred to in Hindu Vedas between 2000 and 1400 BCE, in the Atharvaveda. By the 10th century CE, it has been suggested that it was referred to by some in India as "food of the gods".[116] Cannabis use eventually became a ritual part of the Hindu festival of Holi. One of the earliest to use this plant in medical purposes was Korakkar, one of the 18 Siddhas.[117][118] The plant is called Korakkar Mooli in the Tamil language, meaning Korakkar's herb.[119][120]
A number of people who have used cannabis to fight cancer, have later died of the cancer. I’m concerned that what may have killed many of these people, is that a minor change in the growing conditions of the cannabis plants, reduced the potency of whichever ingredients have the anti-cancer effect. The people kept dosing themselves with their oils or tinctures, but the oils and tinctures no longer contained enough cancer-fighting agents to defeat the cancer, and the people had no way of measuring this.
"The import value of hemp-based products imported and sold in the United States is difficult to estimate accurately. For some traded products, available statistics have only limited breakouts or have been expanded only recently to capture hemp subcategories within the broader trade categories for oilseeds and fibers. Reporting errors are evident in some of the trade data, since reported export data for hemp from Canada do not consistently match reported U.S. import data for the same products (especially for hemp seeds).
In the EU and Canada, hemp has often been grown as a dual-purpose crop, i.e. for both fiber and oilseed. In France, dual purpose hemp is typically harvested twice—initially the upper seed-bearing part of the stems is cut and threshed with a combine, and subsequently the remaining stems are harvested. Growing hemp to the stage that mature seeds are present compromises the quality of the fiber, because of lignification. As well, the hurds become more difficult to separate. The lower quality fiber, however, is quite utilizable for pulp and non-woven usages.
The DCE/SP began funding eradication programs in Hawaii and California in 1979.  The program rapidly expanded to include programs in 25 states by 1982.  By 1985, all 50 states were participating in the DCE/SP.  In 2015, the DEA continued its nation-wide cannabis eradication efforts, providing resources to support the 128 state and local law enforcement agencies that actively participate in the program.  This assistance allows the enhancement of already aggressive eradication enforcement activities throughout the nation.  In 2017, the DEA continued its nation-wide cannabis eradication efforts, providing resources to support the 126 state and local law enforcement agencies that actively participate in the program.   This assistance allows the enhancement of already aggressive eradication enforcement activities throughout the nation.  In 2017, the DCE/SP was responsible for the eradication of 3,078,418 cultivated outdoor cannabis plants and 303,654 indoor plants for a total of 3,382,072 marijuana plants.  In addition, the DCE/SP accounted for 4,502 arrests and the seizure in excess of 20.5 million dollars of cultivator assets.  The program also removed 2,829 weapons from cannabis cultivators. 

There are lots of reasons to invest in hardy Doc Marten boots, but the process of actually breaking them in? Extremely painful. Last December, I found myself hobbling back to my apartment with new-Doc battle wounds — a cut on my ankle and swollen, blistering feet. On a lark, I used the supposedly miraculous CBD lotion from Lord Jones. I can’t believe I’m saying this, but it worked.

The problem is, it’s not easy to know what you’re actually ingesting, or if it’ll actually change how you feel. At best, CBD in America exists in a confusing state of quasi-legality and yet-to-be-realized potential. Experts estimate that the market for it could balloon to $22 billion by 2022, but with cannabis and hemp laws changing rapidly across the country, the chemical is almost entirely unregulated on the consumer market, with no end-product labeling or composition standards to help shoppers understand what they’re buying.

Cannabis use and psychotic symptoms and disorders are associated in the general population (see, for example, Degenhardt and Hall, 2001; Tien and Anthony, 1990) and in clinical samples of patients with schizophrenia (Mueser et al., 1992; Warner et al., 1994; Hambrecht and Hafner, 1996). The major contending hypotheses to explain the association have been: (i) that cannabis use precipitates schizophrenia in persons who are otherwise vulnerable; (ii) cannabis use is a form of self-medication for schizophrenia; and (iii) that the association arises from uncontrolled residual confounding by variables that predict an increased risk of cannabis use and of schizophrenia (Macleod et al., 2004).
In late 2017, researchers with the University of Guelph in Canada published the first-ever study to document the ideal growing conditions for cannabis. Using liquid organic fertilizer with a PKN ratio of 1.3P–1.7K-4.0N, the experiment tested five increasing rates of fertilization. They also tested two coir-based soil-less growing media, or “substrates.”
There are two possible exceptions to this. The first is that some people, for unknown reasons, just react differently to CBD. According to Dr. Chin, about 5% of people say they feel altered after taking CBD. "Usually they're the same people who have side effects from Advil or Tylenol," she says. You never know how your body will react to any new supplement, so when taking CBD for the first time, do so safely under supervision.
CBD is a cannabis-derived, nonpsychoactive (meaning it won’t get you high) hemp product that’s purportedly good for anxiety and relaxing muscles. The problem is that often you don’t know how much CBD you’re getting in whatever given product. Lord Jones, though, has been touted by everyone from Michelle Williams and Olivia Wilde to Katy Perry for foot relief during big awards shows (where brand-new heels reign). I got a sample from LJ and tried it — skeptically — after Bell told Strategist that she’s been hooked and trying to get everyone she knows onboard.
Cannabis has psychoactive and physiological effects when consumed.[45] The immediate desired effects from consuming cannabis include relaxation and euphoria (the "high" or "stoned" feeling), a general alteration of conscious perception, increased awareness of sensation, increased libido[46] and distortions in the perception of time and space. At higher doses, effects can include altered body image, auditory and/or visual illusions, pseudohallucinations and ataxia from selective impairment of polysynaptic reflexes. In some cases, cannabis can lead to dissociative states such as depersonalization[47][48] and derealization.[49]
Quality is a particular concern, because cannabis plants easily soak up heavy metals from pesticides and other contaminants, Marcu says. If you are buying online, look for a company that documents how it tests its products. (If the website doesn’t indicate this, call and ask.) “Buying from a reputable manufacturer is crucial, because it matters how the plant is cultivated and processed,” Dr. Maroon says. One clue that a company is cutting corners: too low a cost. Good CBD is pricey—a bottle of high-quality capsules is sold in Cohen’s office for $140. But for many, it’s worth the money. Roth spent $60 on her tiny bottle. But when her energy returned the day she started taking CBD, she decided that was a small price to pay.
The Drug Enforcement Agency and the Office of National Drug Control Policy of the US raised concerns over tests conducted from 1995 to 1997 that showed that consumption of hempseed products available during that period led to interference with drug-testing programs for marijuana use. Federal US programs utilize a THC metabolite level of 50 parts per billion in urine. Leson (2000) found that this level was not exceeded by consuming hemp products, provided that THC levels are maintained below 5 ppm in hemp oil, and below 2 ppm in hulled seeds. Nevertheless the presence of even minute trace amounts of THC in foods remains a tool that can be used by those wishing to prevent the hemp oilseed industry from developing.
In 1976, Canadian botanist Ernest Small[66] and American taxonomist Arthur Cronquist published a taxonomic revision that recognizes a single species of Cannabis with two subspecies: C. sativa L. subsp. sativa, and C. sativa L. subsp. indica (Lam.) Small & Cronq.[62] The authors hypothesized that the two subspecies diverged primarily as a result of human selection; C. sativa subsp. sativa was presumably selected for traits that enhance fiber or seed production, whereas C. sativa subsp. indica was primarily selected for drug production. Within these two subspecies, Small and Cronquist described C. sativa L. subsp. sativa var. spontanea Vav. as a wild or escaped variety of low-intoxicant Cannabis, and C. sativa subsp. indica var. kafiristanica (Vav.) Small & Cronq. as a wild or escaped variety of the high-intoxicant type. This classification was based on several factors including interfertility, chromosome uniformity, chemotype, and numerical analysis of phenotypic characters.[52][62][67]
A limited number of studies have examined the effects of cannabis smoking on the respiratory system.[89] Chronic heavy marijuana smoking is associated with coughing, production of sputum, wheezing, and other symptoms of chronic bronchitis.[69] The available evidence does not support a causal relationship between cannabis use and chronic obstructive pulmonary disease.[90] Short-term use of cannabis is associated with bronchodilation.[91] Other side effects of cannabis use include cannabinoid hyperemesis syndrome.[92]