Hi Colleen, it's almost a year later and I'm wondering how you're doing. I'm experiencing a recurrence of Stage 3 ovarian, originally diagnosed in 2011. I've decided to get some chemo, not sold on another 6 cycles though. As a new MMJ patient, I'm still going to go through with Rick Simpson Oil (THC+CBD,) and I just joined a program with my local dispensary to get CBD capsules for $2 each when I order them at least 30 at a time. I hope you're doing well!! I'm off to do more research on dosing. **NOTE: If you have ANY experience with CBD treatment of ovarian cancer, PLEASE respond. Thank you!!


A clinical endocannabinoid deficiency has been postulated to be operative in certain treatment-resistant conditions (Russo 2004), and has received recent support in findings that anandamide levels are reduced over controls in migraineurs (Sarchielli et al 2006), that a subset of fibromyalgia patients reported significant decreased pain after THC treatment (Schley et al 2006), and the active role of the ECS in intestinal pain and motility in irritable bowel syndrome (Massa and Monory 2006) wherein anecdotal efficacy of cannabinoid treatments have also been claimed.
Dispensaries are charging 30 bucks and ounce for Hemp Oil so they have no economic incentive to derive the CBD from Marijuana. I found that it was like pulling teeth, just to get the to admit the CBD oil came from Hemp. They isolate the CBD and then add it back to the Oil. This means there is no THC or Terpenes or any of the beneficial compounds found in marijuana.
• Is there a batch number? You know how you check your raw chicken or bagged lettuce every time there's a recall to make sure the one you bought isn't going to make you sick? You should be able to do that with CBD products too. "This is a huge indicator as to whether they are following good manufacturing practices," says Beatty. "There should be a way to identify this product in case it was improperly made so the company can carry out a recall."

In this report, researchers reviewed 16 previously published studies testing the use of various cannabis-based medicines in the treatment of chronic neuropathic pain and found some evidence that cannabis-based medicines may help with pain relief and reduce pain intensity, sleep difficulties, and psychological distress. Side effects included sleepiness, dizziness, mental confusion. The authors concluded that the potential harm of such medicines may outweigh their possible benefit, however, it should be noted that the studies used a variety of cannabis-based medicines (e.g. inhaled cannabis and sprays and oral tablets containing THC and/or CBD from plant sources or made synthetically), some of which are more likely to result in these side effects than products without THC.
Given its name, you might assume THCV shares psychoactive powers with its potent counterpart, THC. In reality, this cannabinoid is more like a cross between CBD and THC. From the former, it takes its modulating powers. Acting like THC “lite,” THCV like CBD can dampen the effects of a strong high. Yet at higher doses, THCV kicks into a psychoactive stimulant in its own right.
CBD research is still in its infancy because both the substance itself and the cultivation of the plants from which it’s derived have long been illegal in the United States. And despite all those cookies you see for sale, CBD does seem to remain illegal, unless FDA approved. In December, hemp cultivation was legalized nationwide as a provision of the Agriculture Improvement Act of 2018. But the FDA released a statement explicating the agency’s stance on CBD’s legality: In short, the FDA does not recognize a distinction between cannabis- and hemp-derived CBD and, for the time being, considers both to be illegal—especially as a questionably safe food additive. Although CBD isn’t dangerous to healthy people, it can affect how the body metabolizes certain types of medication, which Blessing says could lead to overdose in some cases. (Because of the government shutdown, the FDA is unavailable to explain its stance or enforcement plans in further detail.)

Cannabinoids, terpenoids, and other compounds are secreted by glandular trichomes that occur most abundantly on the floral calyxes and bracts of female plants.[42] As a drug it usually comes in the form of dried flower buds (marijuana), resin (hashish), or various extracts collectively known as hashish oil.[8] In the early 20th century, it became illegal in most of the world to cultivate or possess Cannabis for sale or personal use.

Cognitive effects of cannabis have been reviewed (Russo et al 2002; Fride and Russo 2006), but less study has occurred in therapeutic contexts. Effects of chronic heavy recreational cannabis usage on memory abate without sequelae after a few weeks of abstinence (Pope et al 2001). Studies of components of the Halstead-Reitan battery with Sativex in neuropathic pain with allodynia have revealed no changes vs placebo (Nurmikko et al 2007), and in central neuropathic pain in MS (Rog et al 2005), 4 of 5 tests showed no significant differences. While the Selective Reminding Test did not change significantly on Sativex, placebo patients displayed unexpected improvement.
Sub-lingual CBD drops have helped me enormously with sleeping and with radiation damage pain. I have a cancer that spread from the pelvic area to my sacrum and sciatic nerve and whilst the chemo and radiotherapy saved my life I have been taking MST (morphine derivative) for nerve pain ever since. My tumours are presently all quiet and last March I decided I wanted to stop taking the pain relief drugs, fearing dementia. CBD oil was recommended by my son who has arthritis and, for me, it really works. It’s so good to read an article that isn’t put out by a CBD sales site – I wish it could be properly prescribed and regulated (I’m in the UK) in order to have confidence with purity and dosage.
The gateway effect may appear due to social factors involved in using any illegal drug. Because of the illegal status of cannabis, its consumers are likely to find themselves in situations allowing them to acquaint with individuals using or selling other illegal drugs.[268][269] Utilizing this argument some studies have shown that alcohol and tobacco may additionally be regarded as gateway drugs;[270] however, a more parsimonious explanation could be that cannabis is simply more readily available (and at an earlier age) than illegal hard drugs. In turn alcohol and tobacco are easier to obtain at an earlier point than is cannabis (though the reverse may be true in some areas), thus leading to the "gateway sequence" in those individuals since they are most likely to experiment with any drug offered.[261]
But before you do that, know that all hemp CBD oils are not created equal! A recent study published in the Journal of the American Medical Association found nearly 70 percent of hemp CBD oil sold online was mislabeled. During the Penn Medicine study, researchers analyzed 84 products purchased from 31 companies. Around 42 percent of products were under-labeled, meaning the product contained more CBD than labeled. Twenty-six percent of products contained less CBD than indicated on packaging.

Everything you need to know about CBD oil CBD oil may offer a range of benefits, including reducing pain and inflammation. Evidence shows that the oil does not contain psychoactive properties and so does not have the same effects as marijuana. Here, learn more about CBD oil and its uses, benefits, and risks. We also discuss its legality in the U.S. Read now
Prolonged psychological stress may negatively impact health, and has been cited as a factor in cognitive impairment with aging, depressive illness, and expression of disease.[60] Stress management is the application of methods to either reduce stress or increase tolerance to stress. Relaxation techniques are physical methods used to relieve stress. Psychological methods include cognitive therapy, meditation, and positive thinking, which work by reducing response to stress. Improving relevant skills, such as problem solving and time management skills, reduces uncertainty and builds confidence, which also reduces the reaction to stress-causing situations where those skills are applicable.
I have idiopathic peripheral neuropathy ... the only thing they found that would work is lyrica. I picked up some CBD oil yesterday morning. I am prescribed to take 75 mg of lyrica 3x per day. I took one yesterday morning and have only used the CBD oil since. I bought the Koi brand, flavored, 250 MG. I used a full dropper yesterday late morning and a full dropper yesterday late afternoon. I used it once today (one full dropper) and I am amazingly pain free. 

Not surprisingly, the data we have are messy. Berenson, in his role as devil’s advocate, emphasizes the research that sees cannabis as opening the door to opioid use. For example, two studies of identical twins—in the Netherlands and in Australia—show that, in cases where one twin used cannabis before the age of seventeen and the other didn’t, the cannabis user was several times more likely to develop an addiction to opioids. Berenson also enlists a statistician at N.Y.U. to help him sort through state-level overdose data, and what he finds is not encouraging: “States where more people used cannabis tended to have more overdoses.”
The Spaniards brought hemp to the Americas and cultivated it in Chile starting about 1545.[117] Similar attempts were made in Peru, Colombia, and Mexico, but only in Chile did the crop find success.[118] In July 1605, Samuel Champlain reported the use of grass and hemp clothing by the (Wampanoag) people of Cape Cod and the (Nauset) people of Plymouth Bay told him they harvested hemp in their region where it grew wild to a height of 4 to 5 ft. [119] In May 1607, "hempe" was among the crops Gabriel Archer observed being cultivated by the natives at the main Powhatan village, where Richmond, Virginia is now situated;[120] and in 1613, Samuell Argall reported wild hemp "better than that in England" growing along the shores of the upper Potomac. As early as 1619, the first Virginia House of Burgesses passed an Act requiring all planters in Virginia to sow "both English and Indian" hemp on their plantations.[121] The Puritans are first known to have cultivated hemp in New England in 1645.[117]
Hemp stalk is baled for transportation and long-term storage using traditional farming balers. Large round balers are best for hemp because they allow for more thorough drying as they don’t pack the hemp as tightly as square balers. Hemp should be stored in a dry environment in conditions intended to reduce as much absorbable air moisture as possible. It’s also important to check for wet patches during baling to further avoid mold.
I always tell beginners for CBD use to use full-spectrum. The full-spectrum oils contain a lot of terpenes and other good stuff along with CBD and help much more when you suffer from anxiety attacks. CBDistillery also has a wide range of potencies to choose from. Unlike, FabCBD, which offers only limited capacities, CBDistillery’s oils go up to 5000mg per bottle and it is indeed one of the best CBD oils for pain in the market
Dispensaries are charging 30 bucks and ounce for Hemp Oil so they have no economic incentive to derive the CBD from Marijuana. I found that it was like pulling teeth, just to get the to admit the CBD oil came from Hemp. They isolate the CBD and then add it back to the Oil. This means there is no THC or Terpenes or any of the beneficial compounds found in marijuana.
μ-Opioid receptor agonists (opioids) (e.g., morphine, heroin, hydrocodone, oxycodone, opium, kratom) α2δ subunit-containing voltage-dependent calcium channels blockers (gabapentinoids) (e.g., gabapentin, pregabalin, phenibut) AMPA receptor antagonists (e.g., perampanel) CB1 receptor agonists (cannabinoids) (e.g., THC, cannabis) Dopamine receptor agonists (e.g., levodopa) Dopamine releasing agents (e.g., amphetamine, methamphetamine, MDMA, mephedrone) Dopamine reuptake inhibitors (e.g., cocaine, methylphenidate) GABAA receptor positive allosteric modulators (e.g., barbiturates, benzodiazepines, carbamates, ethanol (alcohol) (alcoholic drink), inhalants, nonbenzodiazepines, quinazolinones) GHB (sodium oxybate) and analogues Glucocorticoids (corticosteroids) (e.g., dexamethasone, prednisone) nACh receptor agonists (e.g., nicotine, tobacco, arecoline, areca nut) Nitric oxide prodrugs (e.g., alkyl nitrites (poppers)) NMDA receptor antagonists (e.g., DXM, ketamine, methoxetamine, nitrous oxide, phencyclidine, inhalants) Orexin receptor antagonists (e.g., suvorexant)
That’s our two cents worth. We are still reserching products with claims of effective pain relief and possibly something will work. As of right now if dot/gov can not point the now abandoned pain management patient to an effective pain management product, not willing to listen to our physicians or VERY negatively affected patients with a maximum, unilateral dosage of opioid medication new “policy”, then where do we turn for real, effective, pain management?
^ Vanyukov MM, Tarter RE, Kirillova GP, Kirisci L, Reynolds MD, Kreek MJ, Conway KP, Maher BS, Iacono WG, Bierut L, Neale MC, Clark DB, Ridenour TA (June 2012). "Common liability to addiction and "gateway hypothesis": theoretical, empirical and evolutionary perspective". Drug and Alcohol Dependence (Review). 123 Suppl 1: S3–17. doi:10.1016/j.drugalcdep.2011.12.018. PMC 3600369. PMID 22261179.
PTSD. My husband suffers chronic PTSD from active military service. We live not far from a large Army base and though my husband served with another counties military we hear stories constantly of family breakdowns over PTSD. It’s not a easy path but I’m hoping one day to find something to stop the endless trips to the psych ward. It’s just not right that those who serve come home to no government help.

With the passage of the 2018 Farm Bill, America will have a chance to counter China’s massive influence in the cannabis hemp industry. But it will mean playing catch-up for the foreseeable future. Currently, hemp cultivation techniques in America lag far behind other crops—it still has to be harvested by hand even. Even though marijuana is legal in China, the country has funded research into the plant and its cultivation, placing it miles ahead of other countries.
Hemp is not the same as marijuana. One really has nothing to do with the other. Hemp was made illegal back in the days when cotton was king in the south and southern cotton plantation owners did not want the competition. They lobbied for, and got a law against hemp being grown nationwide. It never had to do with drugs at that time, and still doesn’t. As always, money and government go hand in hand. Now, recently, South Carolina has legalized growing hemp again, which is the only state in 50 to do so. We will hope for more enlightened agri-business legislation across the nation, soon.
My daughter was in a car accident and she is in bad pain. She had a stomach hernia from a liver operation & the airbags hurt the hernia. She had the nerves burned on one side of her stomach but it didn’t do any good. Now tomorrow she is having the other side done. her accident was over a month ago. I told her to go to a pain management doctor so she could get help. Then I saw this post & sent it to her. She wants to know if it takes time to work – it so how long. Also would it mix with other meds? Thanks for your response.

^ Vanyukov MM, Tarter RE, Kirillova GP, Kirisci L, Reynolds MD, Kreek MJ, Conway KP, Maher BS, Iacono WG, Bierut L, Neale MC, Clark DB, Ridenour TA (June 2012). "Common liability to addiction and "gateway hypothesis": theoretical, empirical and evolutionary perspective". Drug and Alcohol Dependence (Review). 123 Suppl 1: S3–17. doi:10.1016/j.drugalcdep.2011.12.018. PMC 3600369. PMID 22261179.
Although hemp and marijuana are both varieties of cannabis, there is a difference between them. The differences between these cannabis varieties are primarily evident in the way each plant is used. These differences are also documented in the language, laws, and regulations that apply to each variety. In this introduction to hemp, we’ll break down the anatomy, history, use, and legality of the hemp plant to get to the heart of not only what distinguishes it from marijuana, but also what makes it such a viable, versatile commodity.
There is certainly a need to utilize available germplasm sources in order to breed suitable cultivars for North America. A list of the 24 approved cultivars for the 2001 season in Canada is at www.hc-sc.gc.ca/hpb-dgps/therapeut/htmleng/hemp.html. Most of these are regulated by the European Organization of Economic Cooperation and Development (OECD). These cultivars are “approved” for use in Canada not on agricultural criteria, but merely on the basis that they meet the THC criterion. Indeed, most of these are unsuitable or only marginally suitable for Canada (Small and Marcus 2000), and only a very few Canadian cultivars to date have been created. In Canada, every acquisition of hemp grown at a particular place and time must be tested for THC content by an independent laboratory and, under the industrial hemp regulations, fields of hemp with more than 0.3% THC may require destruction (a slight degree of flexibility is generally exercised). Importation of experimental hemp lines (i.e. other than the approved cultivars) requires importation licenses (as well as phytosanitary clearance of the shipment by the Canadian Food Inspection Agency), and the importation licenses require an indication that the THC contents are low.
Cannabis (/ˈkænəbɪs/) is a genus of flowering plants in the family Cannabaceae. The number of species within the genus is disputed. Three species may be recognized: Cannabis sativa, Cannabis indica, and Cannabis ruderalis; C. ruderalis may be included within C. sativa; all three may be treated as subspecies of a single species, C. sativa;[1][2][3][4] or C. sativa may be accepted as a single undivided species.[5] The genus is widely accepted as being indigenous to and originating from Central Asia, with some researchers also including upper South Asia in its origin.[6][7]
Online retailers: Most CBD oils are sold through online retailers. These establishments tend to have the widest product range, and many offer free doorstep delivery. Online retailers also frequently post product reviews, allowing buyers to compare different oils based on customer experiences to determine which is best for them. These reviews can also be used to evaluate the retailer based on customer service, delivery, and product quality.
In the 1990s, European firms introduced lines of hemp oil-based personal care products, including soaps, shampoos, bubble baths, and perfumes. Hemp oil is now marketed throughout the world in a range of body care products, including creams, lotions, moisturizers, and lip balms. In Germany, a laundry detergent manufactured entirely from hemp oil has been marketed. Hemp-based cosmetics and personal care products account for about half of the world market for hemp oil (de Guzman 2001).
PTSD. My husband suffers chronic PTSD from active military service. We live not far from a large Army base and though my husband served with another counties military we hear stories constantly of family breakdowns over PTSD. It’s not a easy path but I’m hoping one day to find something to stop the endless trips to the psych ward. It’s just not right that those who serve come home to no government help.

In the United States, cannabis is overall the number four value crop, and is number one or two in many states including California, New York and Florida, averaging $3,000 per pound ($6,600/kg).[256][257] Some believe it generates an estimated $36 billion market.[258] Some have argued that this estimate is methodologically flawed, and makes unrealistic assumptions about the level of marijuana consumption. Other estimates claiming to correct for this flaw claim that the market is between $2.1-$4.3 billion.[249] The United Nations Office on Drugs and Crime claims in its 2008 World Drug Report that typical U.S. retail prices are $10–15 per gram (approximately $280–420 per ounce). Street prices in North America are known to range from about $40–$400 per ounce ($1.4–$14/g), depending on quality.[259]
Historically, hemp could legally be grown and cultivated for academic research purposes only. However, the legality of hemp growth has changed in the past year. In April 2018, Sen. Mitch McConnell of Kentucky introduced the Hemp Farming Act of 2018, a piece of legislation that proposed legalizing all hemp products at the federal level. The act was incorporated in the 2018 United States Farm Bill, which passed in both the House and Senate in December 2018. Per the farm bill, industrial hemp will be descheduled as a federally controlled substance.

"Following enactment of the 2014 farm bill provision allowing for growing hemp under certain circumstances, several states have quickly been adopting new state laws to allow for cultivation. To date, more than 30 states or territories have enacted or introduced legislation favorable to hemp cultivation (Figure 6). Other states reportedly considering hemp legislation include Alaska, Arizona, Florida, Georgia, Iowa, Kansas, Massachusetts, Mississippi, New Mexico, South Dakota, Texas, and Wisconsin.53 (The status of state actions regarding hemp is changing rapidly, and information differs depending on source.54)
It’s also worth noting that more and more people now use cannabis for medicinal purposes, as it is known to offer pain relief for some chronic conditions, as well as stimulate the appetite for people who are sick and may not feel like eating (such as cancer patients undergoing chemotherapy). Despite evidence that cannabis has medical benefits, you should always discuss your options for medical treatment with your doctor and use medical cannabis under their supervision.

"The term ‘“marihuana” means all parts of the plant Cannabis sativa L., whether growing or not; the seeds thereof; the resin extracted from any part of such plant; and every compound, manufacture, salt, derivative, mixture, or preparation of such plant, its seeds or resin. Such term does not include the mature stalks of such plant, fiber produced from such stalks, oil or cake made from the seeds of such plant, any other compound, manufacture, salt, derivative, mixture, or preparation of such mature stalks (except the resin extracted therefrom), fiber, oil, or cake, or the sterilized seed of such plant which is incapable of germination.140


Hemp is thus profitable and sustainable, two words which have eluded many U.S. farmers as of late. Hemp cultivation could provide much-needed relief as farmers struggle to find markets for millions of bushels of crops during the trade wars. Now, instead of importing an estimated $100 million of hemp products every year, that money will go to American farmers and entrepreneurs.

In addition to the daily pain management program outlined above, many people find they still need a safe way to manage acute flare ups. Whether it’s caused by a recent injury, cold weather, or general aggravation  – we recommend vaporizing CBD isolate to combat these acute pain flare ups. The benefit of vaporizing or dabbing CBD isolate is that the relief can be felt almost instantaneously. CBD isolate is 99% pure CBD and provides a wave of relief that can be felt throughout the whole body.
Fig. 11. Frequency histograms of THC concentration in germplasm collections. Left, collection of E. Small and D. Marcus; of the 167 accessions, 43% had THC levels >0.3%. Right, the collection of the Vavilov Institute, St. Petersburg; of the 278 accessions for which chemical analyses were reported in Anonymous (1975), about 55% had THC levels >0.3%.
Established over 25 years ago, Elixinol is one of the veterans in the CBD industry. Its CBD oils and other similar products were improved overtime to an unbeatable formula. It ships all around the USA. Despite the full spectrum cannabinoids do not include THC – the psychoactive substance in cannabis. Therefore, there are no risks regarding psychoactive effects or legal breaches.
CatryNA49; Cannabis, like Opium poppies, and the substances derived from these plants, were also made illegal as a means of preventing white females, from being seduced, and or raped by male members of minority races; seriously ! In the early 70s Nixon administration officials oversaw the expansion of drug laws, as a means of legally repressing the two groups of Americans, that administration deemed to be their biggest foes; those groups being, African Americans, and the antiwar left. We know the drug war, just like the earlier less repressive drug laws, was initiated as a means of legal political, and racial repression because of the fact that a Nixon adm. official is on film, admitting as much. You can Google that film if you like. Now despite the truth about the drug war being admitted on film, for anyone in the world who has internet access can see, the drug war continues to be waged by politicians; the same politicians by the way, that tens of millions of Americans continue to vote for. I should add, that in the last presidential election, the candidate who promised to refuel the drug war, was the candidate who won that election. Of course what else could you expect, being that we live in the land of the free and the home of the brave ?!

Cannabis has psychoactive and physiological effects when consumed.[45] The immediate desired effects from consuming cannabis include relaxation and euphoria (the "high" or "stoned" feeling), a general alteration of conscious perception, increased awareness of sensation, increased libido[46] and distortions in the perception of time and space. At higher doses, effects can include altered body image, auditory and/or visual illusions, pseudohallucinations and ataxia from selective impairment of polysynaptic reflexes. In some cases, cannabis can lead to dissociative states such as depersonalization[47][48] and derealization.[49]
I just started taking CBD oil , I am on my 2nd Hip replacement surgery due to device failures looking at a 3rd surgery. Has you can imagine the pain, stress and anxiety levels are off the charts. Especially at an otherwise healthy 54 yr women. So i understand from reading posts its best to take it under the tongue. I am taking 1-2 ml a day. I can tell some difference,is your recommended dosage. I am using for pain , stress and sleep. I appreciate your feedback.
Right now, due to arcane laws that are about to change around the world, and strange licensing procedures, cannabis is a supply issue, but that will all change over time.  Cannabis is a plant that can grow in 12 weeks, 16 weeks for some Indica strains.  There will never be a shortage or issue with getting cannabis when it is a plant that can be produced anywhere in the world, in large batches, every 12 weeks.
My Wife had Polio at age 5 and the lingering damage to the L leg and muscle drove her crazy. At age 21 she was using heavy doses of muscle relaxers and pain meds. Needed to bomb herself at night to get some sleep. A Post polio group in West Palm Beach told her about Marijuana and she got some from the Jamaican health aide that was her constant helper. After 5 months she quit all meds. All of them. Slowly came out of the drugged state the meds had caused from 15 years of use. We separated good friends and I know she has gone back to school and getting a degree. All from the help of a plant from Jamaica. I never understood the statement this plant has no viable medical value. Something smells in the politics of this prohibition. Shame.

Of course, though, they offer less potent oils than that, with a product lineup that ranges from 300 mg CBD per bottle to 4,000 mg. Naturally the 4,000 mg option is the most expensive (this is the one that provides the “bomb” 60 mg dose), as it currently sells for $299. For long-term pain and anxiety relief, though, it may be well worth it if it is effective for you and helps replace your regular meds.
The 2018 Farm Bill will radically overhaul America’s relation to hemp and could unleash a hemp renaissance in the coming years that will close the gap between the U.S. and China. As a Schedule 1 substance alongside marijuana, hemp farmers and entrepreneurs in the U.S. have faced many barriers to doing business. Interstate commerce for hemp products was almost non-existent and financing was difficult to come by. But all that is set to change.
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