Moreover, scientists at the Cajal Institute showed promising results in regards to CBD and Multiple Sclerosis. They used animal models and cell cultures to find that CBD reversed inflammatory responses; within only ten days, mice that were used in the study had superior motor skills and showed progression in their condition. To date, there have been well over 20,000 published scientific articles on cannabinoids and their related effects on all sorts of medical ailments.
CBD stands for cannabidiol, one of the major constituents of cannabis. CBD products are made from industrial hemp and come in various forms. Although hemp and cannabis are in the same plant species, CBD products now on the market contain less than 0.3 percent THC (tetrahydrocannabinol), the cannabis compound that gets you high. CBD oil can be mixed into food, either straight or diluted with cooking oil, or it can be heated and its vapors inhaled. You can buy CBD in capsules, liquids, gummies, and sublingual sprays, and it is added to tea, coffee, and smoothies. Business experts estimate that the market for CBD products will reach more than $2 billion in consumer sales in the U.S. within the next four years.
That’s our two cents worth. We are still reserching products with claims of effective pain relief and possibly something will work. As of right now if dot/gov can not point the now abandoned pain management patient to an effective pain management product, not willing to listen to our physicians or VERY negatively affected patients with a maximum, unilateral dosage of opioid medication new “policy”, then where do we turn for real, effective, pain management?


My Wife had Polio at age 5 and the lingering damage to the L leg and muscle drove her crazy. At age 21 she was using heavy doses of muscle relaxers and pain meds. Needed to bomb herself at night to get some sleep. A Post polio group in West Palm Beach told her about Marijuana and she got some from the Jamaican health aide that was her constant helper. After 5 months she quit all meds. All of them. Slowly came out of the drugged state the meds had caused from 15 years of use. We separated good friends and I know she has gone back to school and getting a degree. All from the help of a plant from Jamaica. I never understood the statement this plant has no viable medical value. Something smells in the politics of this prohibition. Shame. 

In the United States, cannabis is overall the number four value crop, and is number one or two in many states including California, New York and Florida, averaging $3,000 per pound ($6,600/kg).[256][257] Some believe it generates an estimated $36 billion market.[258] Some have argued that this estimate is methodologically flawed, and makes unrealistic assumptions about the level of marijuana consumption. Other estimates claiming to correct for this flaw claim that the market is between $2.1-$4.3 billion.[249] The United Nations Office on Drugs and Crime claims in its 2008 World Drug Report that typical U.S. retail prices are $10–15 per gram (approximately $280–420 per ounce). Street prices in North America are known to range from about $40–$400 per ounce ($1.4–$14/g), depending on quality.[259]
CBD has some other very important jobs outside of the endocannabinoid system (ECS). For instance, CBD mildly activates one of the brain’s predominant serotonin receptors (5-HT1A), which may explain CBD’s effects on depression and anxiety. It also acts at the peroxisome proliferator activated receptors (PPARs), which halt the proliferation of cancer cells and convey neuro- and cardioprotection. By interacting with a particular PPAR (gamma), CBD could prove to be a promising new way to prevent alzheimer’s disease and other brain disorders.

Some immediate undesired side effects include a decrease in short-term memory, dry mouth, impaired motor skills and reddening of the eyes.[50] Aside from a subjective change in perception and mood, the most common short-term physical and neurological effects include increased heart rate, increased appetite and consumption of food, lowered blood pressure, impairment of short-term and working memory,[51][52] psychomotor coordination, and concentration.

"The DEA followed up, in October 2001, with publication of an interpretive rule in the Federal Register explaining the basis of its zero-tolerance standard.63 It held that when Congress wrote the statutory definition of marijuana in 1937, it 'exempted certain portions of the Cannabis plant from the definition of marijuana based on the assumption (now refuted) that such portions of the plant contain none of the psychoactive component now known as THC.' Both the proposed rule (which was published concurrently with the interpretive rule) and the final 2003 rule gave retailers of hemp foods a date after which the DEA could seize all such products remaining on shelves. On both rules, hemp trade associations requested and received court-ordered stays blocking enforcement of that provision. The DEA’s interpretation made hemp with any THC content subject to enforcement as a controlled substance.
I don’t know a whole lot about the plants but a friend of mine who did weed told me hamper is just the stem of the cannabis. He would know, I wouldn’t. Sadly though he died June 10 of 2018 of stage 4 lung cancer. He was a heavy smoker and I just couldn’t be around it despite our best efforts to set up a ventilation system to fan the smoke out. I must be allergic to secondhand smoke though because I keep getting bronchitis every time I’m exposed to it for long enough and it doesn’t really take a real long time even under the best conditions. Second hand weed smoke really didn’t help either, with me smoke a smoke and I just can’t be around it as it becomes a serious issue. I’m still struggling with trying to get the junk out of my respiratory system that keeps building up in the very upper part of it
I wouldn’t recommend the Lord Jones cream for deep tissue pain so much as surface-level aches: When I’m feeling pain on the pads of my feet, I rub a pump or two of this stuff on the area, which feels almost like applying lidocaine, except the lotion smells danker. My mother, who’s morally opposed to anything remotely weed-related, even took to it after I slipped her some for her painful, cracked winter hands. When I explained later what CBD was, she said, “Oh,” and after a beat, “I guess I did wonder why I stopped feeling anything.”
“It probably should be called snake oil,” says Tishler. ( your cash.) Not only does hemp oil not have any real health benefits, but it may contain stuff that's actually bad for you. "At the moment what you can buy is less regulated than the potato at the supermarket," says Tishler. When hemp oil is extracted, there's a risk that pesticides, plastics, and heavy metals could make their way in, says Tishler.
Protein. Hemp seeds contain 25%–30% protein, with a reasonably complete amino acid spectrum. About two thirds of hempseed protein is edestin. All eight amino acids essential in the human diet are present, as well as others. Although the protein content is smaller than that of soybean, it is much higher than in grains like wheat, rye, maize, oat, and barley. As noted above, the oilcake remaining after oil is expressed from the seeds is a very nutritious feed supplement for livestock, but it can also be used for production of a high-protein flour.
Recreational cannabis use centers around one chemical: the psychoactive cannabinoid tetrahydrocannabinol (THC). Consuming this chemical induces euphoric and stimulating sensations commonly referred to as a “high.” For most marijuana users, these sensations are pleasurable and enjoyable. For some, however, THC can induce feelings of anxiety and paranoia, especially in large doses.
About 9% of those who experiment with marijuana eventually become dependent according to DSM-IV (1994) criteria.[78] A 2013 review estimates daily use is associated with a 10-20% rate of dependence.[42] The highest risk of cannabis dependence is found in those with a history of poor academic achievement, deviant behavior in childhood and adolescence, rebelliousness, poor parental relationships, or a parental history of drug and alcohol problems.[138] Of daily users, about 50% experience withdrawal upon cessation of use (i.e. are dependent), characterized by sleep problems, irritability, dysphoria, and craving.[117] Cannabis withdrawal is less severe than withdrawal from alcohol.[139]

Generalized pain, for instance, has dozens upon dozens of high profile research and clinical studies that have been carried out in universities and laboratories around the globe. One of the most well-publicized of these studies took place back in 2008, in which results determined that “cannabinoid analgesics (pain relievers) have generally been well tolerated in clinical trials … with acceptable adverse event profiles (meaning acceptable effectiveness for practical use).

CBD oil alleviates physical pain and anxiety – both of which can have a negative impact on sleep. Additionally, CBD oil can actually prolong sleep for some, leading to more rest from night to night. Most medical experts agree that marijuana is not particularly beneficial for individuals with medical conditions and/or mental health disorders, as the THC can increase their symptoms; this makes CBD oil a good alternative option for people with the following sleep disorders and medical conditions.

Because C. sativa has been a neglected crop for so long in North America, there are only negligible genetic resources available on this continent. Most germplasm stocks of hemp are in Europe, and the largest and most important collection is the Vavilov Institute gene bank in Leningrad. Figure 11 shows THC concentrations in the Vavilov collection, as well as in our own collection, largely of European germplasm. A disturbingly high percentage of the collections have THC levels higher than 0.3%, making it difficult to incorporate these into breeding programs.
Apart from Endoca CBD oils, you will also find other similar products, such as isolate, tinctures or creams. Some products are designed for pets too. The range offered by Endoca is not impressive when compared to more prestigious manufacturers, but you can still find anything you might need. Using in house green equipment and procedures for the manufacturing process, Endoca can also afford to keep the prices a little lower.
Cannabis, a drug prepared from the plant Cannabis sativa (including marijuana, resin, and “skunk”), is used widely throughout the world and is especially popular in North America, Western Europe, West and Central Africa, and Oceania (United Nations Office on Drugs and Crime, 2009). Several studies within the past decade have investigated the effect of continuous use of cannabis on psychotic illnesses, specifically schizophrenia. Zammit, Allebeck, Andreasson, Lundberg, and Lewis (2002) in Sweden found that those who smoked cannabis had a twofold increased risk of developing schizophrenia within 15 years. In addition, the researchers also found a dose–response relationship; subjects who used cannabis more heavily (over 50 reported occasions) were six times as likely to develop schizophrenia compared to those who did not use cannabis at all.
"Although many states have established programs under which a farmer may be able to grow industrial hemp under certain circumstances, a grower would still need to obtain a DEA permit and abide by DEA’s strict production controls. This relationship has resulted in some high-profile cases, wherein growers have applied for a permit but DEA has not approved (or denied) a permit to grow hemp, even in states that authorize cultivation under state laws.
Another claim is that Mellon, Secretary of the Treasury and the wealthiest man in America at that time, had invested heavily in DuPont's new synthetic fiber, nylon, and believed[dubious – discuss] that the replacement of the traditional resource, hemp, was integral to the new product's success.[128][133][134][135][136][137][138][139] The company DuPont and many industrial historians dispute a link between nylon and hemp, nylon became immediately a scarce commodity.[clarification needed] Nylon had characteristics that could be used for toothbrushes (sold from 1938) and very thin nylon fiber could compete with silk and rayon in various textiles normally not produced from hemp fiber, such as very thin stockings for women.[132][140][141][142][143]
Hemp can be used as a "mop crop" to clear impurities out of wastewater, such as sewage effluent, excessive phosphorus from chicken litter, or other unwanted substances or chemicals. Additionally, hemp is being used to clean contaminants at the Chernobyl nuclear disaster site, by way of a process which is known as phytoremediation—the process of clearing radioisotopes and a variety of other toxins from the soil, water, and air.[46]
I work well under pressure, but being extremely busy at work has almost made me less productive—I'm constantly distracted by email, Slack, and the people around me, to the point where getting my work done becomes difficult. This week, however, I've found it easier to put my blinders on, block out all distractions (especially social distractions) and focus on one task at a time. I think this is partly related to the lessened anxiety—I feel more frazzled and off task when my anxiety is running high. It almost feels like a newfound sense of clarity and calm that enables me to focus.
Health, as defined by the World Health Organization (WHO), is "a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity."[1][2] This definition has been subject to controversy, as it may have limited value for implementation.[3][4][5] Health may be defined as the ability to adapt and manage physical, mental and social challenges throughout life.[6]
Prolonged psychological stress may negatively impact health, and has been cited as a factor in cognitive impairment with aging, depressive illness, and expression of disease.[60] Stress management is the application of methods to either reduce stress or increase tolerance to stress. Relaxation techniques are physical methods used to relieve stress. Psychological methods include cognitive therapy, meditation, and positive thinking, which work by reducing response to stress. Improving relevant skills, such as problem solving and time management skills, reduces uncertainty and builds confidence, which also reduces the reaction to stress-causing situations where those skills are applicable.
Another concern is about medications with which CBD might interact. This won’t be an issue with most drugs, says Sunil Kumar Aggarwal, M.D., Ph.D., a palliative medicine physician and scientist who studies cannabis and integrates it into his Seattle medical practice. The exceptions are blood thinners, IV antibiotics, and other drugs whose exact dosing is crucial and must be monitored closely, he says. (Of course, if you have a health problem, talk to your doctor before using CBD, and never take it instead of seeing your physician for a serious condition.)
"Following enactment of the 2014 farm bill provision allowing for growing hemp under certain circumstances, several states have quickly been adopting new state laws to allow for cultivation. To date, more than 30 states or territories have enacted or introduced legislation favorable to hemp cultivation (Figure 6). Other states reportedly considering hemp legislation include Alaska, Arizona, Florida, Georgia, Iowa, Kansas, Massachusetts, Mississippi, New Mexico, South Dakota, Texas, and Wisconsin.53 (The status of state actions regarding hemp is changing rapidly, and information differs depending on source.54)
An important way to maintain your personal health is to have a healthy diet. A healthy diet includes a variety of plant-based and animal-based foods that provide nutrients to your body. Such nutrients give you energy and keep your body running. Nutrients help build and strengthen bones, muscles, and tendons and also regulate body processes (i.e. blood pressure). The food guide pyramid is a pyramid-shaped guide of healthy foods divided into sections. Each section shows the recommended intake for each food group (i.e. Protein, Fat, Carbohydrates, and Sugars). Making healthy food choices is important because it can lower your risk of heart disease, developing some types of cancer, and it will contribute to maintaining a healthy weight.[44]
With that stereotype now changing in addition to the outbreak of legal marketplaces in 33 states, we’re seeing a boom in cross-industry trends where major corporate and investment players are starting to enter the cannabis sector or at least signal willingness to do so. These trends are proving so strong that companies are starting to think it’s important to get in the game or risk being left behind later. That’s why major brands are either dipping a toe into the water or laying the groundwork for a cannonball-level splash when the Green Rush finally breaks.
"Probably indigenous to temperate Asia, C. sativa is the most widely cited example of a “camp follower.” It was pre-adapted to thrive in the manured soils around man’s early settlements, which quickly led to its domestication (Schultes 1970). Hemp was harvested by the Chinese 8500 years ago (Schultes and Hofmann 1980). For most of its history, C. sativa was most valued as a fiber source, considerably less so as an intoxicant, and only to a limited extent as an oilseed crop. Hemp is one of the oldest sources of textile fiber, with extant remains of hempen cloth trailing back 6 millennia. Hemp grown for fiber was introduced to western Asia and Egypt, and subsequently to Europe somewhere between 1000 and 2000 BCE. Cultivation in Europe became widespread after 500 CE. The crop was first brought to South America in 1545, in Chile, and to North America in Port Royal, Acadia in 1606. The hemp industry flourished in Kentucky, Missouri, and Illinois between 1840 and 1860 because of the strong demand for sailcloth and cordage (Ehrensing 1998). From the end of the Civil War until 1912, virtually all hemp in the US was produced in Kentucky."
In some areas where cannabis use had been historically tolerated, new restrictions were instituted, such as the closing of cannabis coffee shops near the borders of the Netherlands,[222] and closing of coffee shops near secondary schools in the Netherlands.[223] In Copenhagen, Denmark in 2014, mayor Frank Jensen discussed possibilities for the city to legalize cannabis production and commerce.[224]

Ten years ago hemp cultivation was illegal in Germany, England, Canada, Australia, and other countries. Essential to overcoming governmental reluctance in each country was the presentation of an image that was business-oriented, and conservative. The merits of environmentalism have acquired some political support, but unless there is a reasonable possibility that hemp cultivation is perceived as potentially economically viable, there is limited prospect of having anti-hemp laws changed. Strong support from business and farm groups is indispensable; support from pro-marijuana interests and what are perceived of as fringe groups is generally counterproductive. It is a combination of prospective economic benefit coupled with assurance that hemp cultivation will not detrimentally affect the enforcement of marijuana legislation that has led most industrially advanced countries to reverse prohibitions against growing hemp. Should the US permit commercial hemp cultivation to resume, it will likely be for the same reasons.

Despite its centrality in human cultures across the globe, the European taxonomists who bequeathed Cannabis sativa its name didn’t quite get it right. When Carolus Linneaus came to naming the marijuana plant’s genus, he thought there was only one species, instead of the three we now know exist. Hence the confusion surrounding the fact that there are three distinct species of the genus Cannabis sativa, one of which is the sativa species.

CBD Pain