In the mid 1990s, the EU provided subsidization for hemp cultivation of ca. $1,050/ha. This support was instrumental in developing a hemp industry in western Europe. However, no comparable support is available in North America, and indeed those contemplating entering into hemp cultivation are faced with extraordinary costs and/or requirements in connection with licensing, security, THC analysis, and record keeping. Those involved in value-added processing and distribution are also faced with legal uncertainties and the regular threat of idiosyncratic, indeed irrational actions of various governments. Simply displaying a C. sativa leaf on advertising has led to the threat of criminal charges in the last decade in several G8 countries. Attempting to export or import hemp products among countries is presently a most uncertain activity.
Concerns are frequently noted with new drug-drug interactions, but few have resulted in Sativex RCTs despite its adjunctive use with opiates, many other psychoactive analgesic, antidepressant and anticonvulsant drugs (Russo 2006a), possibly due to CBD ability to counteract sedative effects of THC (Nicholson et al 2004). No effects of THC extract, CBD extract or Sativex were observed in a study of effects on the hepatic cytochrome P450 complex (Stott et al 2005b). On additional study, at 314 ng/ml cannabinoid concentration, Sativex and components produced no significant induction on human CYP450 (Stott et al 2007). Thus, Sativex should be safe to use in conjunction with other drugs metabolized via this pathway.
If your intention is to help treat chronic pain, then you may want to start out with a lower dose, and then proceed from there. If you notice effective results, you can downsize the dose, or likewise you can always up the dose until positive results are achieved. The key is to only increase your dosage in small increments so that you are able to pinpoint exactly how much CBD oil it takes to treat your condition. Be advised, though, that you should not exceed the recommended daily doses that are listed on the bottle and you should consult with a physician.
Studies at Bejing's Hemp Research Center revealed the variety of plant uses, prompting China to expand its hemp production which is a mere fraction of its world-leading cotton production. China not only has the product, but they have the cultivation techniques and commercial technologies to capitalize on that supply. And they are ramping up to leverage their competitive hemp advantage, expecting an eager demand from U.S. manufacturers given hemp's rise in popular applications.
Scutching: Passing the stalks through a series of rollers to break apart the hemp fibers. During this step, the woody core is pushed out and separated from the pliable fibers. This is another step where proper drying comes into play. The sweet spot between 10% and 15% moisture is key here. If the stalks are too dry, they will be crushed into a powder. If they are too moist, they won’t break and separate properly.

For some, a sore muscle on your lower back may feel better after using a CBD patch. For others, a headache might respond well to a CBD tincture. Pain is a universal feeling, but we respond differently and our bodies react in different ways depending on our overall health. The variety of ways in which CBD is consumed allows customers to pick a method based on their specific condition and their personal preference. For example, someone with sensitive lungs who doesn’t like smoking may prefer treating their pain with CBD capsules. Someone who takes a lot of pills, in general, may enjoy the experience of vaporizing. CBD is a naturally occurring chemical compound found in the cannabis and hemp plants. It does not produce the difficult side effects that those on prescription opioids commonly experience.
Similarly, while Sativex and smoked cannabis have not been employed in the same clinical trial, comparisons of side effect profiles can be made on the basis of SAFEX studies of Sativex for over a year and up to several years in MS and other types of neuropathic pain (Russo 2006b; Wade et al 2006), and government-approved research programs employing standardized herbal cannabis from Canada for chronic pain (Lynch et al 2006) and the Netherlands for general conditions (Janse et al 2004; Gorter et al 2005) over a period of several months or more. As is evident in Figure 2 (Figure 2), all adverse events are more frequently reported with herbal cannabis, except for nausea and dizziness, both early and usually transiently reported with Sativex (see (Russo 2006b) for additional discussion).
Settlements which date from c. 2200–1700 BCE in the Bactria and Margiana contained elaborate ritual structures with rooms containing everything needed for making drinks containing extracts from poppy (opium), hemp (cannabis), and ephedra (which contains ephedrine).[114] Although there is no evidence of ephedra being used by steppe tribes, they engaged in cultic use of hemp. Cultic use ranged from Romania to the Yenisei River and had begun by 3rd millennium BC Smoking hemp has been found at Pazyryk.[115]
CBD, or cannabidiol, is a cannabinoid found in the hemp plant. As we’ve discovered more about the human species as well as the plants that we’ve learned of the immense health value that CBD brings to the table. It has quickly become a staple supplement for millions who seek a natural alternative to dangerous pharmaceuticals, alien to nature’s perfect remedies.
Other desirable features of hemp fibers are strength and durability (particularly resistance to decay), which made hemp useful in the past for rope, nets, sail-cloth, and oakum for caulking. During the age of sailing ships, Cannabis was considered to provide the very best of canvas, and indeed this word is derived from Cannabis. Several factors combined to decrease the popularity of hemp in the late 19th and early 20th centuries. Increasing limitation of cheap labor for traditional production in Europe and the New World led to the creation of some mechanical inventions, but too late to counter growing interest in competitive crops. Development of other natural fibers as well as synthetic fibers increased competition for hemp’s uses as a textile fiber and for cordage. Hemp rag had been much used for paper, but the 19th century introduction of the chemical woodpulping process considerably lowered demand for hemp. The demise of the sail diminished the market for canvas. Increasing use of the plant for drugs gave hemp a bad image. All this led to the discontinuation of hemp cultivation in the early and middle parts of the 20th century in much of the world where cheap labor was limited. In the 19th century softer fabrics took over the clothing market, and today, hemp constitutes only about 1% of the natural fiber market. At least some production of hemp for fiber still occurs in Russia, China, the Ukraine, Poland, Hungary, the countries of the former Yugoslavia, Romania, Korea, Chile, and Peru. There has been renewed interest in England, Australia, and South Africa in cultivating fiber hemp. Italy has an outstanding reputation for high-quality hemp, but productivity has waned for the last several decades. In France, a market for high-quality paper, ironically largely cigarette paper, has developed (such paper is completely free of the intoxicating resin). Modern plant breeding in Europe has produced several dozen hemp strains, although by comparison with other fiber crops there are relatively few described varieties of hemp. Since World War II, breeding has been concerned most particularly with the development of monoecious varieties. Gehl (1995) reviewed fiber hemp development in Canada in the early 20th century, and concluded that the prospects for a traditional fiber industry were poor. However, as outlined below, there are now many non-traditional usages for hemp fiber which require consideration. Hemp long fiber is one of the strongest and most durable of natural fibers, with high tensile strength, wet strength, and other characteristics that make it technically suited for various industrial products (Karus and Leson 1996).

^ Klein C, Karanges E, Spiro A, Wong A, Spencer J, Huynh T, Gunasekaran N, Karl T, Long LE, Huang XF, Liu K, Arnold JC, McGregor IS (November 2011). "Cannabidiol potentiates Δ⁹-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats". Psychopharmacology. 218 (2): 443–457. doi:10.1007/s00213-011-2342-0. PMID 21667074.


While CBD is considered the major non-psychoactive component of cannabis, in studies using varied doses, routes of administration, and combination or whole products with THC, a number of side effects have been reported, including anxiety, changes in appetite and mood, diarrhea, dizziness, drowsiness, dry mouth, low blood pressure, mental confusion, nausea, and vomiting.
Other “minor phytocannabinoids” in cannabis may also contribute relevant activity (McPartland and Russo 2001). Cannabichromene (CBC) is the third most prevalent cannabinoid in cannabis, and is also anti-inflammatory (Wirth et al 1980), and analgesic, if weaker than THC (Davis and Hatoum 1983). Cannabigerol (CBG) displays sub-micromolar affinity for CB1 and CB2 (Gauson et al 2007). It also exhibits GABA uptake inhibition to a greater extent than THC or CBD (Banerjee et al 1975), suggesting possible utilization as a muscle relaxant in spasticity. Furthermore, CBG has more potent analgesic, anti-erythema and lipooxygenase blocking activity than THC (Evans 1991), mechanisms that merit further investigation. It requires emphasis that drug stains of North American (ElSohly et al 2000; Mehmedic et al 2005), and European (King et al 2005) cannabis display relatively high concentrations of THC, but are virtually lacking in CBD or other phytocannabinoid content.

Cannabidiol is insoluble in water but soluble in organic solvents such as pentane. At room temperature, it is a colorless crystalline solid.[42] In strongly basic media and the presence of air, it is oxidized to a quinone.[43] Under acidic conditions it cyclizes to THC,[44] which also occurs during pyrolysis (smoking).[45] The synthesis of cannabidiol has been accomplished by several research groups.[46][47][48]
If you live in a state where CBD is legal for your condition, it’s best to buy it from a state-regulated dispensary. But even there, oversight is uneven. “I feel safe being a cannabis consumer in Colorado, since the state tracks everything from seed to sale, but I didn’t the first few years after cannabis became legal,” when the rules were still taking shape, says Robyn Griggs Lawrence, the Boulder author of The Cannabis Kitchen Cookbook, which features recipes for cannabis edibles.
Hemp, (Cannabis sativa), also called industrial hemp, plant of the family Cannabaceae cultivated for its fibre (bast fibre) or its edible seeds. Hemp is sometimes confused with the cannabis plants that serve as sources of the drug marijuana and the drug preparation hashish. Although all three products—hemp, marijuana, and hashish—contain tetrahydrocannabinol (THC), a compound that produces psychoactive effects in humans, the variety of cannabis cultivated for hemp has only small amounts of THC relative to that grown for the production of marijuana or hashish.
Activities such as lifting heavy objects at work, being always on your feet, or doing yard work on the weekends can all put strain and duress on your joints. When you continuously put pressure on your joints, it can hinder and even damage your joint movement. With Hemp Bombs’ CBD Pain Freeze, we provide you with an applicable solution designed to deter joint pain and help improve your day to day mobility.
I am currently going through red skin syndrome/topical steroid withdrawal. The only cure as of now is time(6 months to 3 years) and waiting out horrible eczema-like flares. My main issue is burning/tingling skin that is almost constant. Steroids close off blood vessels and when you stop them they 'wake' up causing this nerve discomfort/pain. I've been smoking medical cannabis for the duration of my recovery(1.5 years) and It's done wonders except that the flare is around my mouth and I'm afraid the smoking is causing more issues.. as well as helping. I need to step up my game and take a different approach. I am wondering how to go about using cbd but I don't know where to start and was wondering if you could help. Thank you

CBD has proven neuroprotective effects and its anti-cancer properties are being investigated at several academic research centers in the United States and elsewhere. A 2010 brain cancer study by California scientists found that CBD “enhances the inhibitory effects of THC on human glioblastoma cell proliferation and survival.” This means that CBD makes THC even more potent as an anticancer substance. Also in 2010, German researchers reported that CBD stimulates neurogenesis, the growth of new brain cells, in adult mammals.
Until 2017, products containing cannabidiol marketed for medical purposes were classed as medicines by the UK regulatory body, the Medicines and Healthcare products Regulatory Agency (MHRA) and could not be marketed without regulatory approval for the medical claims.[91] As of 2018, cannabis oil is legal to possess, buy, and sell in the UK, providing the product does not contain more than 0.2% THC and is not advertised as providing a medicinal benefit.[92]

There is great variation in Cannabis sativa, because of disruptive domestication for fiber, oilseed, and narcotic resin, and there are features that tend to distinguish these three cultigens (cultivated phases) from each other. Moreover, density of cultivation is used to accentuate certain architectural features. Figure 5 illustrates the divergent appearances of the basic agronomic categories of Cannabis in typical field configurations.

Cannabis, also referred to as marijuana, has been an integral part of human civilizations for millennia. Both as a medicine and as a recreational substance, cannabis is the most popular illicit drug in the world. Today, the legal landscape that has prohibited marijuana for much of the twentieth century is giving way to decriminalization and full legalization. Legal, commercial cannabis businesses are already making an enormous economic impact.

AC/DC: A Sativa-dominant phenotype of Cannatonic, this cultivar boasts one of the highest ratios of CBD to THC, clocking in at 20:1. AC/DC is claimed to help reduce pain, anxiety, depression and migraines while reducing symptoms in patients with epilepsy, some forms of cancer, and multiple sclerosis. This cultivar’s pinene-rich terpene profile offers potent clear-headed pain relief.
While CBD can be extracted from non-hemp varieties of the plant, hemp-derived CBD is less restricted by the government because of its inherently low levels of THC. CBD from hemp is legal for sale in most US states, while CBD products derived from non-hemp varieties can contain noticeable amounts of THC, and are therefore subject to stricter laws and regulations.
Feminized cannabis seeds are designed to produce only female plants.Usually, a cannabis seed can develop into a male or female plant; the entire process is determined by the sex expressing X and Y chromosomes. "Feminization" is a process of conditioning female plants to obtain male pollen needed for seed production.A plant with two X chromosomes will be female 99% of the time, while regular cannabis seeds (XY genetic set) sometimes have a tendency to produce more male than female individuals.

Not until the end of the 20th century was the specific mechanism of action of THC at the neuronal level studied.[citation needed] Researchers have subsequently confirmed that THC exerts its most prominent effects via its actions on two types of cannabinoid receptors, the CB1 receptor and the CB2 receptor, both of which are G protein-coupled receptors.[142] The CB1 receptor is found primarily in the brain as well as in some peripheral tissues, and the CB2 receptor is found primarily in peripheral tissues, but is also expressed in neuroglial cells.[143] THC appears to alter mood and cognition through its agonist actions on the CB1 receptors, which inhibit a secondary messenger system (adenylate cyclase) in a dose-dependent manner. These actions can be blocked by the selective CB1 receptor antagonist rimonabant (SR141716), which has been shown in clinical trials to be an effective treatment for smoking cessation, weight loss, and as a means of controlling or reducing metabolic syndrome risk factors.[144] However, due to the dysphoric effect of CB1 receptor antagonists, this drug is often discontinued due to these side effects.[145]

Drug policy is always clearest at the fringes. Illegal opioids are at one end. They are dangerous. Manufacturers and distributors belong in prison, and users belong in drug-treatment programs. The cannabis industry would have us believe that its product, like coffee, belongs at the other end of the continuum. “Flow Kana partners with independent multi-generational farmers who cultivate under full sun, sustainably, and in small batches,” the promotional literature for one California cannabis brand reads. “Using only organic methods, these stewards of the land have spent their lives balancing a unique and harmonious relationship between the farm, the genetics and the terroir.” But cannabis is not coffee. It’s somewhere in the middle. The experience of most users is relatively benign and predictable; the experience of a few, at the margins, is not. Products or behaviors that have that kind of muddled risk profile are confusing, because it is very difficult for those in the benign middle to appreciate the experiences of those at the statistical tails. Low-frequency risks also take longer and are far harder to quantify, and the lesson of “Tell Your Children” and the National Academy report is that we aren’t yet in a position to do so. For the moment, cannabis probably belongs in the category of substances that society permits but simultaneously discourages. Cigarettes are heavily taxed, and smoking is prohibited in most workplaces and public spaces. Alcohol can’t be sold without a license and is kept out of the hands of children. Prescription drugs have rules about dosages, labels that describe their risks, and policies that govern their availability. The advice that seasoned potheads sometimes give new users—“start low and go slow”—is probably good advice for society as a whole, at least until we better understand what we are dealing with.
The clinical trials performed with Sativex have recently been assessed in two independent review articles (Barnes 2006; Pérez 2006). In a Phase II clinical trial in 20 patients with neurogenic symptoms (Wade et al 2003), Tetranabinex, Nabidiolex, and Sativex were tested in a double-blind RCT vs placebo (Table 1). Significant improvement was seen with both Tetranabinex and Sativex on pain (especially neuropathic), but post-hoc analysis showed symptom control was best with Sativex (p < 0.0001), with less intoxication than with THC-predominant extract.
Hemp Bombs CBD Pain Freeze is the perfect soothing solution for your pain, cramp, joint and muscle problems. A full dose of CBD is combined with a cold therapy rub to provide the user with long lasting relief. CBD is a well-known pain reliever and anti-inflammatory that is kind to a user's skin. As well as 99% pure CBD, Hemp Bombs Pain Rub is formulated with other natural ingredients like Aloe Vera to enhance the healing potential of the product. At each stage of product development, Hemp Bombs ensures the highest quality CBD from top quality ingredients to conscientious manufacturing practices.

Living a healthy life means making lifestyle choices that support your physical, mental, spiritual, and emotional well-being. Managing your health can be challenging at times; while one facet of your wellness demands more attention than others, you may end up struggling to maintain a good balance in other areas. To be of sound body, mind, and spirit, it’s important to pay attention to all aspects of health—your mental, emotional, and spiritual sides all play a role in your physical welfare, and vice versa. A state of optimal well-being means more than just the absence of disease or disorder; it also means having the resources to cope with problems and circumstances beyond your control and recover from difficult or troubling situations. This intersection between health and behavior can help you prevent or at least delay chronic illness, and steer you to make better decisions about your well-being.
So true. Hearst and Rockefeller did not want Hemp or any form of Cannabis interfering with their lucrative paper, pharmaceutical and oil industries. Hemp is versatile and renewable. It can be used for food, medicine, fuel, paper, clothing, plastic, building materials; just about anything paper and oil is used for. These bastard wealthy people have done a disservice to all people and for the sake of lining their already copiously rich pockets. They and those like them are criminals of the worst order
^ Blest-Hopley G, Giampietro V, Bhattacharyya S (May 2018). "Residual effects of cannabis use in adolescent and adult brains - A meta-analysis of fMRI studies". Neuroscience and Biobehavioral Reviews. 88: 26–41. doi:10.1016/j.neubiorev.2018.03.008. PMID 29535069. This may reflect the multitude of cognitive tasks employed by the various studies included in these meta-analyses, all of which involved performing a task thereby requiring the participant to reorient their attention and attempt to solve the problem at hand and suggest that greater engagement of this region indicates less efficient cognitive performance in cannabis users in general, irrespective of their age.
CBD is a 5-HT1A receptor agonist, which may also contribute to an anxiolytic effect.[156] This likely means the high concentrations of CBD found in Cannabis indica mitigate the anxiogenic effect of THC significantly.[156] The cannabis industry claims that sativa strains provide a more stimulating psychoactive high while indica strains are more sedating with a body high.[157] However this is disputed by researchers.[158]

Plant, (kingdom Plantae), any multicellular eukaryotic life-form characterized by (1) photosynthetic nutrition (a characteristic possessed by all plants except some parasitic plants and underground orchids), in which chemical energy is produced from water, minerals, and carbon dioxide with the aid of pigments and the radiant energy of the Sun, (2)…
CBD may offer an option for treating different types of chronic pain. A study from the European Journal of Pain showed, using an animal model, CBD applied on the skin could help lower pain and inflammation due to arthritis. Another study demonstrated the mechanism by which CBD inhibits inflammatory and neuropathic pain, two of the most difficult types of chronic pain to treat. More study in humans is needed in this area to substantiate the claims of CBD proponents about pain control.
Our Full Spectrum Hemp Extract has endless possibilities as an add in, like in this berry smoothie 😍✨ Link in bio to purchase! . #fullspectrum #hempextract #cbd #cbdsmoothie #smoothies #berrysmoothie #lucefarm #cleaneating #healthydiet #healthandwellness #healthinspo #eatingwell #realsimple #morningmotivation #fruitforbreakfast #organic #organicfarmers #vermontgrown #cafes #coffeeshops #barista #healthyliving #mctoil #mct #coconutoilbenefits #fitness #plantmedicine #sustainableliving #refusethestraw #noplasticstraws
Cost is another consideration. Most CBD oils are sold in concentrations of 300 to 750 mg, although this may range from less than 100 mg to more than 2,000. A good indicator of price-point is the cost per milligram. Low-cost CBD oils usually fall between five and 10 cents per mg; mid-range prices are 11 to 15 cents per mg; and higher-end oils cost 16 cents per mg or higher. Given these varying per-milligram costs, a bottle of CBD oil may be priced anywhere from $10 or less to $150 or more.

Hemp plants are almost always cultivated outdoors, as opposed to marijuana plants, which are mostly planted in greenhouse or indoor settings. Because hemp is susceptible to the same predators diseases and insects that attack marijuana, the hemp industry employs a technique called crop rotation, in which alternating crops are planted in the same place, to avoid any buildup of these organisms and allow nutrients to return to the soil. The specific order of crop rotation and types of crops being rotated with hemp will depend on the location of the farm. Hemp is also used as a rotational crop at farms where it is not the primary agricultural product.


Cannabis use has the hallmark pathologic features shared by all substance use disorders. Like other drugs of abuse, Cannabis causes compulsive drug-seeking behaviors, loss of self-control, withdrawal symptoms, and the propensity to relapse.57 Cannabis use disorder has been recognized as a bona fide disorder and has been included in the most recent version of the Diagnostic and Statistical Manual of Mental Disorders (fifth edition).58 Long-term clinical outcomes for Cannabis use disorder may be less severe than for other drugs of abuse but the addictive processes appears to be very similar. Animal models of addiction have clearly supported the notion that Cannabis has addictive properties.
All of those uses make hemp a profitable cash crop for suffering farmers, with some early commercial growers reporting $100 per-acre more profit on hemp than canola. Hemp grown for CBD oil, on the other hand, can take in $8,000 per acre versus $600 per acre for corn. In particular, hemp can be a boon for arid western states. According to Pacific Standard,  
Various strains of "medical marijuana" are found to have a significant variation in the ratios of CBD-to-THC, and are known to contain other non-psychotropic cannabinoids.[60] Any psychoactive marijuana, regardless of its CBD content, is derived from the flower (or bud) of the genus Cannabis. Non-psychoactive hemp (also commonly-termed industrial hemp), regardless of its CBD content, is any part of the cannabis plant, whether growing or not, containing a ∆-9 tetrahydrocannabinol concentration of no more than 0.3% on a dry-weight basis.[61] Certain standards are required for legal growing, cultivating, and producing the hemp plant. The Colorado Industrial Hemp Program registers growers of industrial hemp and samples crops to verify that the dry-weight THC concentration does not exceed 0.3%.[61]
One of the most curious uses of hemp is as a fence to prevent pollen transfer in commercial production of seeds. Isolation distances for ensuring that seeds produced are pure are considerable for many plants, and often impractical. At one point in the 1980s, the only permitted use of hemp in Germany was as a fence or hedge to prevent plots of beets being used for seed production from being contaminated by pollen from ruderal beets. The high and rather inpenetrable hedge that hemp can produce was considered unsurpassed by any other species for the purpose. As well, the sticky leaves of hemp were thought to trap pollen. However, Saeglitz et al. (2000) demonstrated that the spread of beet pollen is not effectively prevented by hemp hedges. Fiber (i.e. tall) cultivars of hemp were also once used in Europe as wind-breaks, protecting vulnerable crops against wind damage. Although hemp plants can lodge, on the whole very tall hemp is remarkably resistant against wind.
CBD research is still in its infancy because both the substance itself and the cultivation of the plants from which it’s derived have long been illegal in the United States. And despite all those cookies you see for sale, CBD does seem to remain illegal, unless FDA approved. In December, hemp cultivation was legalized nationwide as a provision of the Agriculture Improvement Act of 2018. But the FDA released a statement explicating the agency’s stance on CBD’s legality: In short, the FDA does not recognize a distinction between cannabis- and hemp-derived CBD and, for the time being, considers both to be illegal—especially as a questionably safe food additive. Although CBD isn’t dangerous to healthy people, it can affect how the body metabolizes certain types of medication, which Blessing says could lead to overdose in some cases. (Because of the government shutdown, the FDA is unavailable to explain its stance or enforcement plans in further detail.)
Without arguing the merits of the above contentions, we point out that the legitimate use of hemp for non-intoxicant purposes has been inhibited by the continuing ferocious war against drug abuse. In this atmosphere, objective analysis has often been lacking. Unfortunately both proponents and opponents have tended to engage in exaggeration. Increasingly, however, the world is testing the potential of hemp in the field and marketplace, which surely must be the ultimate arbiters. De Guzman (2001), noting the pessimistic USDA report, observed that “Nevertheless, others point to the potential of [the] market. Hemp products have a growing niche market of their own, and the market will remain healthy and be well supported with many competing brands.”
The Marinol patient monograph cautions that patients should not drive, operate machinery or engage in hazardous activities until accustomed to the drug’s effects (http://www.solvaypharmaceuticals-us.com/static/wma/pdf/1/3/1/9/Marinol5000124ERev52003.pdf). The Sativex product monograph in Canada (http://www.bayerhealth.ca/display.cfm?Object_ID=272&Article_ID=121&expandMenu_ID=53&prevSubItem=5_52) suggests that patients taking it should not drive automobiles. Given that THC is the most active component affecting such abilities, and the low serum levels produced in Sativex therapy (vide supra), it would be logical that that patients may be able to safely engage in such activities after early dose titration and according to individual circumstances, much as suggested for oral dronabinol. This is particularly the case in view of a report by an expert panel (Grotenhermen et al 2005) that comprehensively analyzed cannabinoids and driving. It suggested scientific standards such as roadside sobriety tests, and THC serum levels of 7–10 ng/mL or less, as reasonable approaches to determine relative impairment. No studies have demonstrated significant problems in relation to cannabis affecting driving skills at plasma levels below 5 ng/mL of THC. Prior studies document that 4 rapid oromucosal sprays of Sativex (greater than the average single dose employed in therapy) produced serum levels well below this threshold (Russo 2006b). Sativex is now well established as a cannabinoid agent with minimal psychotropic effect.
^ Jump up to: a b c d Boggs, Douglas L; Nguyen, Jacques D; Morgenson, Daralyn; Taffe, Michael A; Ranganathan, Mohini (6 September 2017). "Clinical and preclinical evidence for functional interactions of cannabidiol and Δ9-tetrahydrocannabinol". Neuropsychopharmacology. 43 (1): 142–154. doi:10.1038/npp.2017.209. ISSN 0893-133X. PMC 5719112. PMID 28875990. 

While most supplements have a single recommended dose, CBD is different. The amount of CBD you take depends on your doctor’s recommendations and your own research into how CBD will work for your unique needs. In general, it’s smart to start with a medium dose of CBD. This way, you can increase or decrease the dose as needed. In addition, it’s recommended to start with one half ML (half a dropper) of CBD oil, because you can always take more if needed.
The DCE/SP began funding eradication programs in Hawaii and California in 1979.  The program rapidly expanded to include programs in 25 states by 1982.  By 1985, all 50 states were participating in the DCE/SP.  In 2015, the DEA continued its nation-wide cannabis eradication efforts, providing resources to support the 128 state and local law enforcement agencies that actively participate in the program.  This assistance allows the enhancement of already aggressive eradication enforcement activities throughout the nation.  In 2017, the DEA continued its nation-wide cannabis eradication efforts, providing resources to support the 126 state and local law enforcement agencies that actively participate in the program.   This assistance allows the enhancement of already aggressive eradication enforcement activities throughout the nation.  In 2017, the DCE/SP was responsible for the eradication of 3,078,418 cultivated outdoor cannabis plants and 303,654 indoor plants for a total of 3,382,072 marijuana plants.  In addition, the DCE/SP accounted for 4,502 arrests and the seizure in excess of 20.5 million dollars of cultivator assets.  The program also removed 2,829 weapons from cannabis cultivators.
To my understanding, neither CBD nor THC are effective for “severe” pain; rather, they work better for mild to moderate chronic pain. Often, with severe pain, the dosage of opiates can be decreased with concomitant use of medical cannabis or CBD and that decrease in dose makes their use safer. Concurrent use of THC does increase the analgesic effect of CBD, but it also adds the “high” which some people do not want as a side effect.
Grant says this may lead to a “dampening” or mellowing of some neurochemical processes, including those linked to pain. “CBD may also react with other receptors, like those for serotonin, and it may have actions that reduce the inflammatory molecules produced whenever there is tissue damage or bacteria coming in,” he says. “But we really don’t know the mechanisms.”

In November 2015, Uttarakhand became the first state of India to legalize the cultivation of hemp for industrial purposes.[235] Usage within the Hindu and Buddhist cultures of the Indian subcontinent is common, with many street vendors in India openly selling products infused with cannabis, and traditional medical practitioners in Sri Lanka selling products infused with cannabis for recreational purposes and well as for religious celebrations.[236] It was criminalized in the Indian subcontinent by the Dutch and then the British. India and Sri Lanka have allowed cannabis to be taken in the context of traditional culture for recreational/celebratory purposes and also for medicinal purposes.[236]


It’s also important to select CBD oil products based on your concentration preferences. Some forms of CBD oil – such as vapors and tinctures – normally have higher-than-average concentrations, whereas sprays and topicals tend to have lower concentrations. Remember: higher concentration means more pronounced effects, but not necessarily mean higher quality.

Retting is generally done in the field (Fig. 46, 47). This typically requires weeks. The windrows should be turned once or twice. If not turned, the stems close to the ground will remain green while the top ones are retted and turn brown. When the stalks have become sufficiently retted requires experience—the fibers should have turned golden or grayish in color, and should separate easily from the interior wood. Baling can be done with any kind of baler (Fig. 48). Stalks should have less than 15% moisture when baled, and should be allowed to dry to about 10% in storage. Bales must be stored indoors. Retted stalks are loosely held together, and for highest quality fiber applications need to be decorticated, scutched, hackled, and combed to remove the remaining pieces of stalks, broken fibers, and extraneous material. The equipment for this is rare in North America, and consequently use of domestically-produced fiber for high quality textile applications is extremely limited. However, as described above relatively crude fiber preparations also have applications.


Hi, I am new to trying CBD oil for chronic pain. I really do not know where to begin . For 14 yrs now I have been living with chronic back pain. I have had surgery, numerous shots, etc. I have been on pain ( opiods) for 14 yrs. I am looking to find something not only for my pain, depression, not sleeping ,anxiety, etc. I know that most my problems come from my chronic pain and being on pain meds for so long. Can anyone please recommend a CBD oil product and strength for me. I have been reading all the reviews and I just need someone to help. I have talked to my Doctor about it and he feels that I should try, but didn’t recommend what.
Henry Ford recognized the utility of hemp in early times. In advance of today’s automobile manufacturers, he constructed a car with certain components made of resin stiffened with hemp fiber (Fig. 19). Rather ironically in view of today’s parallel situation, Henry Ford’s hemp innovations in the 1920s occurred at a time of crisis for American farms, later to intensify with the depression. The need to produce new industrial markets for farm products led to a broad movement for scientific research in agriculture that came to be labeled “Farm Chemurgy,” that today is embodied in chemical applications of crop constituents. 

One area where CBD is clearly helpful: the treatment of seizures associated with one form of epilepsy. A 2017 New England Journal of Medicine study found ingesting oral CBD dramatically cut down most patients’ seizure frequency—a finding that prompted the FDA to support the approval of one CBD drug for use in the treatment of some epilepsy patients.
Like everything else in the U.S it is buyer beware. I was told that the 30 dollar a bottle Hemp Oil, would not work becasue I was “Skeptical.” I had asked exactly these questions at a Dispensary. The CBD Craze is mostly hype. It does little or nothing for pain, or anything else. The only thing I have seen is that when it is derived from marijuana in the for of a Salve with the a small amount of THC in it, it might help with arthritis topically.
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"The survey covers the harvest of 2013, related to a total cultivation area of 15,700 ha. The first figure shows the development of the cultivation area since 1993. Between 1993 and 1996 the cultivation of industrial hemp was legalised in most of the member states, others followed later. In 2011 the cultivation area decreased to its lowest value since 1994 (ca. 8,000 ha), but increased in 2012, 2013 and 2014, to finally reach 25,000 ha in 2015. In 2016 a further increase is expected. The main cultivation member states are France and The Netherlands. In recent years, many new European countries started or expanded their hemp cultivation, mainly for the production of hemp seeds.
Last year, the Hemp Industries Association (HIA) estimated the total retail value of all hemp products sold in the U.S. at $620 million. Sadly, all of the raw hemp materials were imported from other countries. (More on that later.) Hemp is an attractive rotation crop for farmers. As it grows, hemp breathes in CO2, detoxifies the soil, and prevents soil erosion. What’s left after harvest breaks down into the soil, providing valuable nutrients.

There are a few things that are better about CBD Pain Cream than taking prescriptions. First of all, prescriptions can take a while to kick in. So, if you’re in pain in the morning, it can be almost impossible to get out of bed. On the other hand, CBD Chiro-Cream can work in as little as five minutes’ post-application. † So, you can get on with your day when you use this product. The magic of CBD Pain Cream is that it helps calm your body’s pain receptors. Every single person has an endocannabinoid system (ECS) that is responsible for telling your brain when you’re in pain, anxious, or uncomfortable.
Hello Roy,We will attempt to help you as much as possible.As you know CBD is a new treatment option so there are almost no scientific studies and very few case studies available. However as a general rule the best thing to do is just to start.We say this because everyones body metabolizes CBD at different rates. So the best way to find the proper dosage for you is just to start. The good news is that feeling sleepy is about the only side effect of overdosing CBD, so experimentation is pretty safe.What we recommend on our site is to start with 25mg of CBD taken as often as you need it throughout the day. If you find this works stick with it. If you find you need more, or are having to take it too many times during the day, then take more such as 50mg with each serving.Which oil should you use that will ship to the UK? We have reviewed all the top CBD oil products and have found Endoca to be the best and most powerful oil on the market. If you are going to use CBD hemp oil we recommend using raw CBD oil. This is the most natural and has the highest amount of plant constituents present which increases effectiveness.The best oil to start with is Endoca Raw Hemp Oil 2000mg. If taking 50mg a day this tube will last you 40 days. If you are taking 200mg a day you will need to purchase 3 tubes per month.Read the full review here: https://cbdoilreview.org/endoca-raw-hemp-oil-2000mg/Buy the product here: https://cbdoilreview.org/product/endoca-raw-hemp-oil-2000mg/Endoca ships to the UK from their European headquarters so you are good to go there. If you have any other questions please contact us using the form below or give us a call, we are happy to help!
Cannabis has an ancient history of ritual use and is found in pharmacological cults around the world. Hemp seeds discovered by archaeologists at Pazyryk suggest early ceremonial practices like eating by the Scythians occurred during the 5th to 2nd century BC, confirming previous historical reports by Herodotus.[202] It was used by Muslims in various Sufi orders as early as the Mamluk period, for example by the Qalandars.[203] Smoking pipes uncovered in Ethiopia and carbon-dated to around c. AD 1320 were found to have traces of cannabis.[204]
Cannabis is a generic term used to denote the several psychoactive preparations of the plant Cannabis sativa. The major psychoactive consituent in cannabis is ∆-9 tetrahydrocannabinol (THC). Compounds which are structurally similar to THC are referred to as cannabinoids. In addition, a number of recently identified compounds that differ structurally from cannabinoids nevertheless share many of their pharmacological properties. The Mexican term 'marijuana' is frequently used in referring to cannabis leaves or other crude plant material in many countries. The unpollinated female plants are called hashish. Cannabis oil (hashish oil) is a concentrate of cannabinoids obtained by solvent extraction of the crude plant material or of the resin.
"Acreage in hemp cultivation worldwide has been mostly flat to decreasing, reported at about 200,000 acres globally in 2011.31 Although variable year-to-year, global production has increased overall from about 250 million pounds in 1999 to more than 380 million pounds in 2011, mostly due to increasing production of hemp seed (Figure 3). Upward trends in global hemp seed production roughly track similar upward trends in U.S. imports of hemp seed and oil, mostly for use in hemp-based foods, supplements, and body care products (Table 1).

Anecdotal evidence from patients is becoming increasingly widespread as well. Morgan Freeman suffers from pain and he was quoted saying, “I have fibromyalgia pain in my arm and the only thing that offers any relief is marijuana.” Whoopi Goldberg also uses cannabis to treat her daily pain from glaucoma and has even launched a line of medical cannabis products geared towards women suffering from menstrual pain.
Like everything else in the U.S it is buyer beware. I was told that the 30 dollar a bottle Hemp Oil, would not work becasue I was “Skeptical.” I had asked exactly these questions at a Dispensary. The CBD Craze is mostly hype. It does little or nothing for pain, or anything else. The only thing I have seen is that when it is derived from marijuana in the for of a Salve with the a small amount of THC in it, it might help with arthritis topically.

Plant, (kingdom Plantae), any multicellular eukaryotic life-form characterized by (1) photosynthetic nutrition (a characteristic possessed by all plants except some parasitic plants and underground orchids), in which chemical energy is produced from water, minerals, and carbon dioxide with the aid of pigments and the radiant energy of the Sun, (2)…
Like everything else in the U.S it is buyer beware. I was told that the 30 dollar a bottle Hemp Oil, would not work becasue I was “Skeptical.” I had asked exactly these questions at a Dispensary. The CBD Craze is mostly hype. It does little or nothing for pain, or anything else. The only thing I have seen is that when it is derived from marijuana in the for of a Salve with the a small amount of THC in it, it might help with arthritis topically.
Cannabis is used in three main forms: marijuana, hashish and hash oil. Marijuana is made from dried flowers and leaves of the cannabis plant. It is the least potent of all the cannabis products and is usually smoked or made into edible products like cookies or brownies (see Factsheet: Marijuana Edibles). Hashish is made from the resin (a secreted gum) of the cannabis plant. It is dried and pressed into small blocks and smoked. It can also be added to food and eaten. Hash oil, the most potent cannabis product, is a thick oil obtained from hashish. It is also smoked.
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