I do hope this will be approved since the one was approved of someone attacking marijuanna supporting opiate pills yet lying on marijuanna to keep rights to their pain pills. First no I don’t agree the handling of how the war on opiates were done, its lead to sky rocketing of heroin not just for high some pain as they felt it all they had left but but becomes problem fast, heroin is the end of the line solution ! Patients like me stage 4 cancer up recurrence were just cold turkey took off left pain meds left to feel cancer and opiate withdrawal pain. I too never overtook my pain meds. You don’t have to be addicted you will become dependent as your body will stop making natural opiate receptors. Two years of pure suffering goes by and I give in to medical marijuana and cannibas oil and my life changed! I went from hospice 2mo max to hospice leaving my health improved so much! A surgery where tumors on bile ducts, liver was cancelled, the pain gone vomiting stopped and MRI confirmed tumors gone. So sorry if taken little offense to sthg be said sthg like “they making marijuana legal & these younger-older folks get high while I take my opiates as presribed & they save me” as I don’t care much for the head feeling of marijuanna if was honest give me the feeling from an opiate anyday. No-one thinks they have a problem with pain pills for most dangerous reasons “my doctor gave to me, i take only as needed, its legal” other than pain relief & quality of life opiates give you no saving your life. Opiates can not cure conditions, slow or kill cancer or near what cannibas-marijuanna is known to do. Until medical marijuana I continued to slowly lose my battle to cancer, not blaming pain meds at all only saying they provided no medical benefit other than pain relief and pleasure feeling. Upon the marijuana..it medical miracle..went from dying with 2mo left to live here 8mo later putting makeup on again living. I only use minimum amount early morning and late night. I have went on to teach myself about other things like enzymes and other plant life to alkaline, anti-inflammatory my body. I support opiates when needed but highly support medical marijuana and cannibas oil.. I just don’t think to inform others educationaly something that is not true judging others. Marijuana is not addictive unless the brain is not fully developed but even then in kids it can save their life: seizures etc. Noone has ever overdosed or died of marijuana per DEA. You can’t say that for opiates. Although I advocate for being fair to true pain patients on opiates. I also advocate to legalize marijuanna but because someone has a preference or dependency on one should not make them want them come to a forum helping so many medically to advocate for their vice to insult others medical choice… Read more »

Hemp Bombs is based in Tampa, Florida, and in addition to focusing on the purity and therapeutic effectiveness of their products, are dedicated to establishing themselves as a top brand in the industry with a specific target audience. One of our personal favorite products of theirs is the flavored CBD vape liquids, which are some of the best-tasting CBD vape juices we’ve ever had.
Cannabis made another leap forward in 1964 when Israeli scientist Dr. Raphael Mechoulam identified the structure of delta-9-tetrahydrocannabinol, or THC. This discovery earned him godfather status of modern cannabis. This particular discovery allowed science to understand THC’s nature as a psychoactive compound in cannabis as well as CBD’s non-intoxicating but vastly therapeutic benefits.

Thank you for your questions. Marijuana and hemp are two extremely different strains of the same cannabis sativa plant that have been bred over thousands of years to have entirely different purposes. (Hemp is not the male version of the marijuana plant.) They both contain CBD. Hemp only contains CBD whereas marijuana contains CBD and perhaps a hundred or so other chemicals with a variety of functions, such as THC, the molecule that makes people “high”. Any medicine can have different effects on different people. For example, Benadryl makes some people sleepy yet can make others wide-awake. So, it is not inconsistent for a particular medicine to cause a symptom in one person and to help alleviate it in another. So while many people experience relaxation with CBD, so people do experience the “paradoxical” effect of irritability.
All CBD products start out the same way: as an extract from the leaves and flowers of cannabis plants. At Green Roads, we only extract CBD from hemp, defined as any variety of cannabis plant containing less than 0.3% THC by dry weight. Cannabinoids and terpenes are produced by tiny glands on the leaves and flowers of cannabis plants known as trichomes. The compounds produced by these trichomes give cannabis both its rich aroma and its nutraceutical effects.

Several studies have demonstrated the therapeutic effects of cannabinoids for nausea and vomiting in the advanced stages of illnesses such as cancer and AIDS. Dronabinol (tetrahydrocannabinol) has been available by prescription for more than a decade in the USA. Other therapeutic uses of cannabinoids are being demonstrated by controlled studies, including treatment of asthma and glaucoma, as an antidepressant, appetite stimulant, anticonvulsant and anti-spasmodic, research in this area should continue. For example, more basic research on the central and peripheral mechanisms of the effects of cannabinoids on gastrointestinal function may improve the ability to alleviate nausea and emesis. More research is needed on the basic neuropharmacology of THC and other cannabinoids so that better therapeutic agents can be found.
The word cannabis is from Greek κάνναβις (kánnabis) (see Latin cannabis),[135] which was originally Scythian or Thracian.[136] It is related to the Persian kanab, the English canvas and possibly even to the English hemp (Old English hænep).[136] In modern Hebrew, קַנַּבּוֹס qannabōs (modern pronunciation: [kanaˈbos]) is used but there are those who have theorized that it was referred to in antiquity as קני בושם q'nei bosem, a component of the biblical anointing oil.[137][138] Old Akkadian qunnabtu, Neo-Assyrian and Neo-Babylonian qunnabu were used to refer to the plant meaning "a way to produce smoke".[139][140][141]
Hemp is used to make a variety of commercial and industrial products including rope, textiles, clothing, shoes, food, paper, bioplastics, insulation, and biofuel.[5] The bast fibers can be used to make textiles that are 100% hemp, but they are commonly blended with other fibers, such as flax, cotton or silk, as well as virgin and recycled polyester, to make woven fabrics for apparel and furnishings. The inner two fibers of the plant are more woody and typically have industrial applications, such as mulch, animal bedding and litter. When oxidized (often erroneously referred to as "drying"), hemp oil from the seeds becomes solid and can be used in the manufacture of oil-based paints, in creams as a moisturizing agent, for cooking, and in plastics. Hemp seeds have been used in bird feed mix as well.[13] A survey in 2003 showed that more than 95% of hemp seed sold in the European Union was used in animal and bird feed.[14]
CBD’s action within the brain and body is quite complicated. To date, scientists have discovered more than a dozen different mechanisms of action, or ways that CBD affect us. It’s very likely that the beneficial effects of CBD are a result of the total of its activation of all of these biological pathways, not a single one in particular. Much more research is needed to fully understand the mechanisms by which CBD relieves ailments such as anxiety and seizures.
The DCE/SP began funding eradication programs in Hawaii and California in 1979.  The program rapidly expanded to include programs in 25 states by 1982.  By 1985, all 50 states were participating in the DCE/SP.  In 2015, the DEA continued its nation-wide cannabis eradication efforts, providing resources to support the 128 state and local law enforcement agencies that actively participate in the program.  This assistance allows the enhancement of already aggressive eradication enforcement activities throughout the nation.  In 2017, the DEA continued its nation-wide cannabis eradication efforts, providing resources to support the 126 state and local law enforcement agencies that actively participate in the program.   This assistance allows the enhancement of already aggressive eradication enforcement activities throughout the nation.  In 2017, the DCE/SP was responsible for the eradication of 3,078,418 cultivated outdoor cannabis plants and 303,654 indoor plants for a total of 3,382,072 marijuana plants.  In addition, the DCE/SP accounted for 4,502 arrests and the seizure in excess of 20.5 million dollars of cultivator assets.  The program also removed 2,829 weapons from cannabis cultivators.
But even though it's infiltrating pretty much every corner of the wellness world (hi, vegan CBD brownies!) many people still find CBD a little confusing—especially when it comes to figuring out the right way to use it and how to make sure the stuff you're buying is, you know, actually legit. Below, we asked experts to answer the most pressing questions about CBD.
Topicals represent a newer emerging market in medical marijuana products geared toward health and beauty. Cannabinoids can be absorbed through the skin for certain therapeutic benefits without any psychoactivity. Additionally, the essential oils in hemp and cannabis provide many benefits for skin health. From moisturizers to shampoos and deodorants, medical cannabis products continue to diversify.
Cannabidiol—more commonly abbreviated as CBD—isn’t psychoactive and, apparently to the man’s disappointment, won’t get you high. Instead, many people report that consuming it makes them feel less anxious, helps them sleep, or eases joint pain. Over the past two years, CBD in the form of oils and supplements has become widely distributed across the United States, even in places with no level of cannabis legalization. Now the trend’s new frontier is food. My first clue that it had hit some kind of critical mass was seeing a local restaurant put a sign out front announcing the debut of CBD empanadas. From design-oriented Instagram seltzer to your local pizza place, brands and restaurants want you to order some CBD and eat your feelings. 

^ Nadulski T, Pragst F, Weinberg G, Roser P, Schnelle M, Fronk EM, Stadelmann AM (December 2005). "Randomized, double-blind, placebo-controlled study about the effects of cannabidiol (CBD) on the pharmacokinetics of Delta9-tetrahydrocannabinol (THC) after oral application of THC verses standardized cannabis extract". Ther Drug Monit. 27 (6): 799–810. doi:10.1097/01.ftd.0000177223.19294.5c. PMID 16306858.
Hemp hasn't always been on the wrong side of the authorities. The Puritans brought hemp with them to New England in 1645 and Europeans were growing it even earlier in Chile. George Washington planted hemp as one of several crops at his Mount Vernon estate. However, hemp's popularity waned in America as other plants used for textiles such as cotton and jute became more widely available. The U.S. Navy briefly campaigned for more hemp farming during World War II to supply ropes for ships. But the federal government continued restrictions on hemp after the war.
In December 2012, the U.S. state of Washington became the first state to officially legalize cannabis in a state law (Washington Initiative 502) (but still illegal by federal law),[227] with the state of Colorado following close behind (Colorado Amendment 64).[228] On January 1, 2013, the first marijuana "club" for private marijuana smoking (no buying or selling, however) was allowed for the first time in Colorado.[229] The California Supreme Court decided in May 2013 that local governments can ban medical marijuana dispensaries despite a state law in California that permits the use of cannabis for medical purposes. At least 180 cities across California have enacted bans in recent years.[230]
Many monoecious varieties have also been described,[20] in which individual plants bear both male and female flowers.[21] (Although monoecious plants are often referred to as "hermaphrodites", true hermaphrodites – which are less common in Cannabis – bear staminate and pistillate structures together on individual flowers, whereas monoecious plants bear male and female flowers at different locations on the same plant.) Subdioecy (the occurrence of monoecious individuals and dioecious individuals within the same population) is widespread.[22][23][24] Many populations have been described as sexually labile.[25][26][27]
The reason so many people are interested in cannabis products that don’t make them high, proponents say, is that CBD helps with everything from pain and nausea to rheumatoid arthritis, cancer, Crohn’s disease, and dementia. CBD is anti-inflammatory, anti-anxiety, antibacterial, immunosuppressive, and more, says Joseph Cohen, D.O., a cannabis doctor in Boulder, CO.
"Skin dryness and itchiness, in particular, are very serious problems in atopic dermatitis, which often lead to additional complications, such as opportunistic infections. In any event, it seems that the reduction of atopic symptomology observed in this study is a direct result of ingested hempseed oil. These preliminary results confirm anecdotal observations of improved skin quality after ingesting modest amounts of hempseed oil on a daily basis over a relatively short period of time."
In September 2018, following its approval by the FDA for rare types of childhood epilepsy,[13] Epidiolex was rescheduled (by the Drug Enforcement Administration) as a Schedule V drug to allow for its prescription use.[14] This change applies only to FDA-approved products containing no more than 0.1 percent THC.[14] This allows GW Pharmaceuticals to sell Epidiolex, but it does not apply broadly and all other CBD-containing products remain Schedule I drugs.[14] Epidiolex still requires rescheduling in some states before it can be prescribed in those states.[65][66]
CBD was first discovered in 1940 by Roger Adams, a prominent organic chemist at the University of Illinois. Shortly thereafter, other scientists began testing isolated cannabinoids on lab animals; notably, Walter S. Loewe ran trials on mice and rabbits with the cannabinoids THC, CBD and CBN. He found that CBD produced no observable effects in the animals’ behavior while THC caused, what he called, a “central excitant action” in rabbits. Despite science’s movement forward, scientists were completely unaware of the cannabinoids’ chemical structure, so no one could tell which specific compound resulted in which effect.
Among members of the public-health community, it is impossible to spend five minutes on the e-cigarette question without getting into an argument. And this is nicotine they are arguing about, a drug that has been exhaustively studied by generations of scientists. We don’t worry that e-cigarettes increase the number of fatal car accidents, diminish motivation and cognition, or impair academic achievement. The drugs through the gateway that we worry about with e-cigarettes are Marlboros, not opioids. There are no enormous scientific question marks over nicotine’s dosing and bio-availability. Yet we still proceed cautiously and carefully with nicotine, because it is a powerful drug, and when powerful drugs are consumed by lots of people in new and untested ways we have an obligation to try to figure out what will happen.
Berenson thinks that we are far too sanguine about this link. He wonders how large the risk is, and what might be behind it. In one of the most fascinating sections of “Tell Your Children,” he sits down with Erik Messamore, a psychiatrist who specializes in neuropharmacology and in the treatment of schizophrenia. Messamore reports that, following the recent rise in marijuana use in the U.S. (it has almost doubled in the past two decades, not necessarily as the result of legal reforms), he has begun to see a new kind of patient: older, and not from the marginalized communities that his patients usually come from. These are otherwise stable middle-class professionals. Berenson writes, “A surprising number of them seemed to have used only cannabis and no other drugs before their breaks. The disease they’d developed looked like schizophrenia, but it had developed later—and their prognosis seemed to be worse. Their delusions and paranoia hardly responded to antipsychotics.”
^ Klein C, Karanges E, Spiro A, Wong A, Spencer J, Huynh T, Gunasekaran N, Karl T, Long LE, Huang XF, Liu K, Arnold JC, McGregor IS (November 2011). "Cannabidiol potentiates Δ⁹-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats". Psychopharmacology. 218 (2): 443–457. doi:10.1007/s00213-011-2342-0. PMID 21667074.

Health science is the branch of science focused on health. There are two main approaches to health science: the study and research of the body and health-related issues to understand how humans (and animals) function, and the application of that knowledge to improve health and to prevent and cure diseases and other physical and mental impairments. The science builds on many sub-fields, including biology, biochemistry, physics, epidemiology, pharmacology, medical sociology. Applied health sciences endeavor to better understand and improve human health through applications in areas such as health education, biomedical engineering, biotechnology and public health.

In the United States, non-FDA approved CBD products are classified as Schedule I drugs under the Controlled Substances Act.[62] This means that production, distribution, and possession of non-FDA approved CBD products is illegal under federal law. In addition, in 2016 the Drug Enforcement Administration added "marijuana extracts" to the list of Schedule I drugs, which it defined as "an extract containing one or more cannabinoids that has been derived from any plant of the genus Cannabis, other than the separated resin (whether crude or purified) obtained from the plant."[63] Previously, CBD had simply been considered "marijuana", which is a Schedule I drug.[62][64]
For now, however, it appears that CBD will remain largely off-limits. The Food and Drug Administration issued a statement saying that despite the new status of hemp, CBD is still considered a drug ingredient and remains illegal to add to food or health products without the agency’s approval, disappointing many hemp advocates, who said they will continue to work to convince the FDA to loosen its CBD rules, the Associated Press reported. The FDA said some hemp ingredients, such as hulled hemp seeds, hemp seed protein and hemp seed oil, are safe in food and won’t require additional approvals.

Cannabis terpenoids also display numerous attributes that may be germane to pain treatment (McPartland and Russo 2001). Myrcene is analgesic, and such activity, in contrast to cannabinoids, is blocked by naloxone (Rao et al 1990), suggesting an opioid-like mechanism. It also blocks inflammation via PGE-2 (Lorenzetti et al 1991). The cannabis sesquiterpenoid β-caryophyllene shows increasing promise in this regard. It is anti-inflammatory comparable to phenylbutazone via PGE-1 (Basile et al 1988), but simultaneously acts as a gastric cytoprotective (Tambe et al 1996). The analgesic attributes of β-caryophyllene are increasingly credible with the discovery that it is a selective CB2 agonist (Gertsch et al 2007), with possibly broad clinical applications. α-Pinene also inhibits PGE-1 (Gil et al 1989), while linalool displays local anesthetic effects (Re et al 2000).


ECS is made up of endocannabinoids and the receptors associated with them. These receptors are literally found from head to toe, and are in such places as the glands, organs, and the brain. While receptors and endocannabinoids are located in all parts of the body, they have different functions depending upon where they are located, with the primary role being to regulate what is referred to as homeostasis or the regulation of the body so that it is at equilibrium.

The 2014 Farm Bill[75] legalized the sale of "non-viable hemp material" grown within states participating in the Hemp Pilot Program.[76] This legislation defined hemp as cannabis containing less than 0.3% of THC delta-9, grown within the regulatory framework of the Hemp Pilot Program.[77] The 2018 Farm Bill allowed for interstate commerce of hemp derived products, though these products still fall under the purview of the FDA.[78][79]
CBD has powerful effects on the liver as well. Have you ever had a prescription that warns you not to take the medicine along with grapefruit? That’s because grapefruit inhibits certain drug-metabolizing enzymes in your liver, resulting in much higher levels of your medication in your bloodstream. CBD does the same thing, so it is wise to discuss your medication regimen with a doctor or pharmacist before engaging in CBD therapy.
In 2017, China imported more than $24 billion in agriculture products from the U.S. The world’s top wheat consumer, China and purchased 1.6 million tons of U.S. wheat worth $391 million. At the same time, China bought $14 billion in soybeans for personal and animal consumption from the U.S. last year--more than any other agricultural commodity, and the country's corn imports from the U.S. were worth $160 million.
Hemp seeds can be eaten raw, ground into hemp meal, sprouted or made into dried sprout powder. Hemp seeds can also be made into a liquid and used for baking or for beverages such as hemp milk and tisanes.[15] Hemp oil is cold-pressed from the seed and is high in unsaturated fatty acids.[16] The leaves of the hemp plant, while not as nutritional as the seeds, are edible and can be consumed raw as leafy vegetables in salads, and pressed to make juice.[17]
Hemp Bombs is based in Tampa, Florida, and in addition to focusing on the purity and therapeutic effectiveness of their products, are dedicated to establishing themselves as a top brand in the industry with a specific target audience. One of our personal favorite products of theirs is the flavored CBD vape liquids, which are some of the best-tasting CBD vape juices we’ve ever had.
With marijuana, apparently, we’re still waiting for this information. It’s hard to study a substance that until very recently has been almost universally illegal. And the few studies we do have were done mostly in the nineteen-eighties and nineties, when cannabis was not nearly as potent as it is now. Because of recent developments in plant breeding and growing techniques, the typical concentration of THC, the psychoactive ingredient in marijuana, has gone from the low single digits to more than twenty per cent—from a swig of near-beer to a tequila shot.
"Given these data limitations, available trade statistics indicate that the value of U.S. imports under categories actually labeled 'hemp,' such as hemp seeds and fibers—which are more often used as inputs for use in further manufacturing—was nearly $78.2 million in 2015. Compared to 2005, when the value of imports totaled $5.6 million, imported hemp products for use as inputs and ingredients has increased sharply. However, import volumes for other products, such as hemp oil and fabrics, are lower (Table 1). Trade data are not available for finished products, such as hempbased clothing or other products including construction materials, carpets, or paper products.
I rubbed some on my feet, and the surface-level pain went away, almost as if lightly numbed. I could wear my Doc Martens again with zero pain, even though my feet still looked, um, not great. I was shocked, especially because other CBD balms I’ve tried — like Leef Organics, Charlotte’s Web, and Mary’s Nutritionals — never had much of an effect. Even other top-rated CBD topicals from Purekana (and sister brand Kushly) never really did the trick. LJ does use activated hemp extract in a broad spectrum formula that includes the whole plant, helping to retain all of the plant’s original terpenes and phytocannabinoids, minus the THC (though that might not explain all of it, since other CBD options I tested use the whole plant, too). I’m no scientist, but I know my dogs stopped hurting.
Put simply, “indica” strains are those associated with a strong body-high, feelings of sedation and relaxation. For this reason, indicas are often thought of as the “heavier” strains of cannabis, offering stronger highs that impact the whole body. They’re popular among marijuana users as pain relieving and sleep-inducing strains. Indicas are especially popular among medical cannabis patients.
The results of the three large European cohort studies have been confirmed in two smaller New Zealand birth cohorts. Arsenault and colleagues (2002) reported a prospective study of the relationship between adolescent cannabis use and psychosis in a New Zealand birth cohort (n = 759). They found a relationship between cannabis use by age 15 and an increased risk of psychotic symptoms by age 26. The relationship did not change when they controlled for other drug use, but it was no longer statistically significant after adjusting for psychotic symptoms at age 11. The latter probably reflected the small number of psychotic disorders observed in the sample. Fergusson et al. (2003) found a relationship between cannabis dependence at age 18 and later symptoms that included those in the psychotic spectrum reported at age 21 in the Christchurch birth cohort. Fergusson and colleagues adjusted for a large number of potential confounding variables, including self-reported psychotic symptoms at the previous assessment, other drug use and other psychiatric disorders, but whether the association represents a link between cannabis use and psychotic symptoms specifically, or more general psychiatric morbidity, remains unclear.

"The different cannabis varieties are also harvested at different times (depending on the growing area), increasing the chance of detection of illegal marijuana, if production is commingled. Because of these differences, many claim that drug varieties of cannabis cannot easily be grown with oilseed or fiber varieties without being easily detected.9 As discussed below, among the visual plant differences are plant height (hemp is encouraged to grow tall, whereas marijuana is selected to grow short and tightly clustered); cultivation (hemp is grown as a single main stalk with few leaves and branches, whereas marijuana is encouraged to become bushy with many leaves and branches to promote flowers and buds); and planting density (hemp is densely planted to discourage branching and flowering, whereas marijuana plants are well-spaced)."
Our bodies contain two types of cannabinoid receptors that are aptly namely, cannabinoid receptor type 1 (CB1) and cannabinoid receptor type 2 (CB2). CB1 receptors are found mostly in the brain. The CB2 receptors, on the other hand, are located throughout the body and play a significant role our immune systems, regulating pain and inflammation. In fact, nearly every type of human disease, including pain-related illnesses, involve some sort of change in CB2 function.

Due to almost a century of misinformation about Cannabis, the distinction between Cannabis and its two primary species — hemp and marijuana — has become unclear to the many and some even consider the three plants to be one in the same. Because of this, the three terms are often used interchangeably, which has created difficulties when understanding the usage and benefits of Hemp vs Marijuana and Cannabis in general.
Grant says this may lead to a “dampening” or mellowing of some neurochemical processes, including those linked to pain. “CBD may also react with other receptors, like those for serotonin, and it may have actions that reduce the inflammatory molecules produced whenever there is tissue damage or bacteria coming in,” he says. “But we really don’t know the mechanisms.” 

A 2012 review found that the THC content in marijuana had increased worldwide from 1970 to 2009.[160] It is unclear, however, whether the increase in THC content has caused people to consume more THC or if users adjust based on the potency of the cannabis. It is likely that the higher THC content allows people to ingest less tar. At the same time, CBD levels in seized samples have lowered, in part because of the desire to produce higher THC levels and because more illegal growers cultivate indoors using artificial lights. This helps avoid detection but reduces the CBD production of the plant.[161]
The other issue with the Medical Marijuana Industry is that they are throwing pain patients under the bus. In order to market their products they are conflating Heroin Addiction, with pain patients taking medically prescribed medications. They overstate the effectiveness for pain control, and present marijuana as a “Cure” for the Opiate Epidemic. They are claiming that Medical Marijuana is a Cure for “Opiate Addiction” in order to sensationalize their claims and make them sound beneficial.
Cannabis consumers have long prized potency (a high THC content) as one of the main factors that makes a particular strain more desirable. Though traditional demand for THC has caused an oversaturation of high-potency products, many consumers are starting to prefer less intense products that are lower in THC and higher in the non-intoxicating compound called cannabidiol (CBD).
With marijuana, apparently, we’re still waiting for this information. It’s hard to study a substance that until very recently has been almost universally illegal. And the few studies we do have were done mostly in the nineteen-eighties and nineties, when cannabis was not nearly as potent as it is now. Because of recent developments in plant breeding and growing techniques, the typical concentration of THC, the psychoactive ingredient in marijuana, has gone from the low single digits to more than twenty per cent—from a swig of near-beer to a tequila shot.

Zammit and colleagues (2002) reported a 27-year follow-up of the Swedish cohort study. This study improved on the earlier study in the following ways: the psychiatric register provided more complete coverage of cases diagnosed with schizophrenia; and there was better statistical control of more potentially confounding variables, including other drug use, IQ, known risk factors for schizophrenia and social integration. Cannabis use at baseline predicted a dose–response relationship between the frequency of cannabis use at age 18 and the risk of schizophrenia during the follow-up. The relationship persisted after statistically controlling for the effects of other drug use and other potential confounding factors, including a history of psychiatric symptoms at baseline. They estimated that 13 percent of cases of schizophrenia could be averted if all cannabis use were prevented.
Success stories like Oliver’s are everywhere, but there’s not a lot of data to back up those results. That’s because CBD comes from cannabis and, like nearly all other parts of the plant, is categorized by the Drug Enforcement Agency (DEA) as a Schedule 1 drug—the most restrictive classification. (Others on that list: heroin, Ecstasy, and peyote.) This classification, which cannabis advocates have tried for years to change, keeps cannabis-derived products, including CBD, from being properly studied in the U.S.
Cannabis terpenoids also display numerous attributes that may be germane to pain treatment (McPartland and Russo 2001). Myrcene is analgesic, and such activity, in contrast to cannabinoids, is blocked by naloxone (Rao et al 1990), suggesting an opioid-like mechanism. It also blocks inflammation via PGE-2 (Lorenzetti et al 1991). The cannabis sesquiterpenoid β-caryophyllene shows increasing promise in this regard. It is anti-inflammatory comparable to phenylbutazone via PGE-1 (Basile et al 1988), but simultaneously acts as a gastric cytoprotective (Tambe et al 1996). The analgesic attributes of β-caryophyllene are increasingly credible with the discovery that it is a selective CB2 agonist (Gertsch et al 2007), with possibly broad clinical applications. α-Pinene also inhibits PGE-1 (Gil et al 1989), while linalool displays local anesthetic effects (Re et al 2000).
With so many companies popping up every day, we’ve done the hard work for you. We bring you the best CBD oil guide and the top 25 brands that made our list based on CBD oil quality, effectiveness, customer service and of course price. Please note, this article is updated constantly, so don’t forget come back from time to time to see the most updated information.
Pain from inflammation can and will likely affect all adults at some point in their lives, and for some, become chronic conditions that interfere with a normal quality of life. Over-the-counter (OTC) and prescription anti-inflammatory medications are easily available, readily prescribed, and very commonly used.  The most common anti-inflammatory medications are called NSAIDs: non-steroidal... Read more
Topicals represent a newer emerging market in medical marijuana products geared toward health and beauty. Cannabinoids can be absorbed through the skin for certain therapeutic benefits without any psychoactivity. Additionally, the essential oils in hemp and cannabis provide many benefits for skin health. From moisturizers to shampoos and deodorants, medical cannabis products continue to diversify.
My husband has RSD and we are considering CBD oil -= I would ask at Hempmed because the spray won't have enough in it. Our dgt';s friend has ovarian cancer and it is shrinking her tumors but the spray would never have been enough. I would get CBD oil and check with Hempmeds to see what they suggest. It isn't cheap but it does work. LOW dose Naltrexone about 4.5 mg is very helpful for RSD and is usually used for getting people off of drugs but is working on turning off the glial cells that surround the nerve that is causing the nerve to scream in pain. We are also using PeaPure that is out of the Netherlands and we are seeing a response, even though small. His other leg touched the painful leg without causing more severe pain. That is progress. We also are using Poison Ivy Cream through Meadowlake Farms that has helped the burning surface pain. Change your diet and get rid of Gluten and Sugar, anything that causes inflammation. This is to allow your own body to work. Absolutely do not use any pain killers as it will turn up your pain. all the Hydrocodone, etc causes neural inflammation and so it will keep cascading higher your pain. Hope this is helpful. Mary
In the 1970s, the taxonomic classification of Cannabis took on added significance in North America. Laws prohibiting Cannabis in the United States and Canada specifically named products of C. sativa as prohibited materials. Enterprising attorneys for the defense in a few drug busts argued that the seized Cannabis material may not have been C. sativa, and was therefore not prohibited by law. Attorneys on both sides recruited botanists to provide expert testimony. Among those testifying for the prosecution was Dr. Ernest Small, while Dr. Richard E. Schultes and others testified for the defense. The botanists engaged in heated debate (outside of court), and both camps impugned the other's integrity.[57][58] The defense attorneys were not often successful in winning their case, because the intent of the law was clear.[65]
A recent study of mice with degenerative disc disease found that they experienced improvement with high doses of CBD. Researchers actually found reduced damage to the spin in their experimental population. While the exact mechanism and reasons for these results are unclear, it is certainly promising. More research needs to be done but this is certainly a good start.
I am a former family doctor and naturopathic physician as well as a medical editor and author, working mostly in academic research. In my practice I have always focused on natural medicine and helped my patients of all ages who haven’t responded to traditional treatments. I also have written a significant number of articles in botanical medicine, addiction, drugs. As of now I'm focused on cannabis researches, especially on cannabidiol, its health benefits and how it can improve life of people with severe diseases. You can read my articles here on CBDreamers
There are a number of issues that can arise from injuries where cannabidiol oil can make a huge difference. Injuries to the neck caused in a car accident, during a sporting event, or through some other kind of activity can be crippling. You can use hemp best CBD oil for neck pain which will not only reduce pain, but make movement in the neck a whole lot easier.
Personal health also depends partially on the social structure of a person's life. The maintenance of strong social relationships, volunteering, and other social activities have been linked to positive mental health and also increased longevity. One American study among seniors over age 70, found that frequent volunteering was associated with reduced risk of dying compared with older persons who did not volunteer, regardless of physical health status.[58] Another study from Singapore reported that volunteering retirees had significantly better cognitive performance scores, fewer depressive symptoms, and better mental well-being and life satisfaction than non-volunteering retirees.[59]
We saw the start of this in 2017, when companies like Constellation Brands, maker of Corona beer, invested in Canopy Growth Corporation. Last year, they increased their ownership stake to 38 percent, infusing an additional $4 billion in the business. At the time of that second investment, Constellation’s CEO Rob Sands said, “This could potentially be one of the most significant global growth opportunities for the next decade.”
Similarly, while Sativex and smoked cannabis have not been employed in the same clinical trial, comparisons of side effect profiles can be made on the basis of SAFEX studies of Sativex for over a year and up to several years in MS and other types of neuropathic pain (Russo 2006b; Wade et al 2006), and government-approved research programs employing standardized herbal cannabis from Canada for chronic pain (Lynch et al 2006) and the Netherlands for general conditions (Janse et al 2004; Gorter et al 2005) over a period of several months or more. As is evident in Figure 2 (Figure 2), all adverse events are more frequently reported with herbal cannabis, except for nausea and dizziness, both early and usually transiently reported with Sativex (see (Russo 2006b) for additional discussion).
Cannabis research suggests medical marijuana could become an effective treatment for diabetic neuropathy. Diabetic neuropathy is a debilitating and sometimes fatal condition caused by diabetes. Diabetics suffer from high blood sugar due to insulin resistance, and this damages nerve cells in the body, causing severe pain. Patients who consumed THC as part of a study found they experienced less pain. Findings are not definitive, however, and further research into cannabis as a treatment for diabetes and associated symptoms is required.
We all know of Charlotte’s Web; the miracle strain that is packed with a high concentration of CBD. The Charlotte’s Web Cannabis Strain was named after Charlotte Figi, who suffers from Dravet syndrome and was experiencing several seizures daily until the Stanley Brothers came up with this powerful strain. Since then, Charlotte’s web has been morphed into various products, including their famous Charlotte’s Web CBD oil.
Because hemp-derived CBD currently lacks labeling and purity standards that are required of cannabis products sold at legal dispensaries, it exists in a regulatory limbo that laws don’t yet address. In the meantime, the Los Angeles County Department of Public Health has announced that starting in July, putting CBD in food products will cost businesses points on their health inspections.

Short-term use increases both minor and major adverse effects.[104] Common side effects include dizziness, feeling tired, vomiting, and hallucinations.[104] Long-term effects of cannabis are not clear.[106] Concerns including memory and cognition problems, risk of addiction, schizophrenia in young people, and the risk of children taking it by accident.[103]
Hemp paper is useful for specialty applications such as currency and cigarette papers where strength is needed. The bast fiber is of greatest interest to the pulp and paper industry because of its superior strength properties compared to wood. However, the short, bulky fibers found in the inner part of the plant (hurds) can also be used to make cheaper grades of paper, apparently without greatly affecting quality of the printing surface. Hemp is not competitive for newsprint, books, writing papers, and general paper (grocery bags, coffee cups, napkins), although there is a specialty or novelty market for those specifically wishing to support the hemp industry by purchasing hemp writing or printing paper despite the premium price (Fig. 17).
The maintenance and promotion of health is achieved through different combination of physical, mental, and social well-being, together sometimes referred to as the "health triangle."[24][25] The WHO's 1986 Ottawa Charter for Health Promotion further stated that health is not just a state, but also "a resource for everyday life, not the objective of living. Health is a positive concept emphasizing social and personal resources, as well as physical capacities."[26]
"In the past there has been ongoing tension between federal and state authorities over state hemp policies. After North Dakota passed its own state law authorizing industrial hemp production in 1999,62 researchers repeatedly applied for, but did not receive, a DEA permit to cultivate hemp for research purposes in the state.63 Also in 2007, two North Dakota farmers were granted state hemp farming licenses and, in June 2007, filed a lawsuit in U.S. District Court (North Dakota) seeking 'a declaratory judgment' that the CSA 'does not prohibit their cultivation of industrial hemp pursuant to their state licenses.'64 The case was dismissed in November 2007.65 The case was appealed to the U.S. Court of Appeals (Eighth Circuit) but was again dismissed in December 2009.66 The farmers filed an appeal in May 2010.67

would take the oil and put about 2 or 3 dots behind his knee and to his surprise, the tingling went away right away. I found this hard to believe, but after hearing from some other people on the benefits of CBD, I decided to give it a try. It didn’t come cheap. I had to pay 50 dollars for an oz. but it was whole plant in full spectrum. The first night that I got restless leg syndrome and went into the bathroom and put 3 dots behind my knees on both legs it was only a matter of seconds before I
The key is to effectively gauge exactly how much CBD oil it takes to start managing your pain. If you start off right away with a maximum dose of a 600 mg tincture, you will have no idea how much of the product it actually took to treat your condition, and how much you wasted (this is also important because you do not want to exceed dosage and end up developing a tolerance to the active cannabinoids).
You are likely very familiar with the dangers that prescription painkillers (and other pharmaceuticals) present. In fact, it’s estimated that the majority of CBD oil users attempt to switch to the all-natural therapy for the precise reason of kicking prescription med habits, which all too often cause an overwhelming array of irritability, sleep disruption, digestive complications, and even thoughts of suicide.
"There is little information about DEA’s permit process and on facilities that are licensed to grow hemp, even for research purposes. Previously reports indicated that DEA had issued a permit for an experimental quarter-acre plot at the Hawaii Industrial Hemp Research Program during the period from 1999 to 2003 (now expired).69 Most reports indicate that DEA continues to be reluctant to grant licenses to grow hemp, even for research purposes.70 Recent indications are that some land grant university researchers may have been granted licenses to conduct hemp research under certain conditions.71
Since then, we’ve seen progress in other areas. Last month, Barneys New York brought cannabis into the world of high-end luxury goods when it announced they would open a boutique focused on selling luxury accessories to cannabis aficionados. “Barneys is courting the Manolo Blahnik-wearing, marijuana smoking crowd,” trumpeted a headline on MarketWatch.
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Truth be told, one of the biggest draws to using CBD oil for pain has been the fact that it has little distinguishable side-effects or contraindications with other medications. In fact, in a massive report that was published by the World Health Organization during last year’s 2017 Expert Committee on Drug Dependence, it was (finally) declared to the world that CBD is a “safe, well tolerated [compound, which] is not associated with any significant adverse public health effects.”
• Speaking of which: Has it been third-party tested? Nearly every expert Health spoke to agreed that your CBD products should be tested by a third party to confirm the label's accuracy. This is a real concern in the industry—take the 2017 Journal of the American Medical Association study, for example, which tested 84 CBD products and found that 26% contained lower doses than stated on the bottle. Look for a quality assurance stamp or certificate of analysis from a third party (aka not the actual brand) or check the retailer's website if you don't see it on the product's label.
According to Delphic analysis by British researchers in 2007, cannabis has a lower risk factor for dependence compared to both nicotine and alcohol.[98] However, everyday use of cannabis may be correlated with psychological withdrawal symptoms, such as irritability or insomnia,[94] and susceptibility to a panic attack may increase as levels of THC metabolites rise.[99][100] However, cannabis withdrawal symptoms are typically mild and are never life-threatening.[101]
PTSD. My husband suffers chronic PTSD from active military service. We live not far from a large Army base and though my husband served with another counties military we hear stories constantly of family breakdowns over PTSD. It’s not a easy path but I’m hoping one day to find something to stop the endless trips to the psych ward. It’s just not right that those who serve come home to no government help.

In the United States, the public's perception of hemp as marijuana has blocked hemp from becoming a useful crop and product,"[55] in spite of its vital importance prior to World War II.[56] Ideally, according to Britain's Department for Environment, Food and Rural Affairs, the herb should be desiccated and harvested towards the end of flowering. This early cropping reduces the seed yield but improves the fiber yield and quality.[57] In these strains of industrial hemp* the tetrahydrocannabinol (THC) content would have been very low.[55]

A wide variety of hemp clothing, footwear, and food products are now available in North America. Some American manufacturers and distributors have chosen to exploit the association of hemp products with marijuana in their advertising. Such marketing is unfortunate, sending the message that some in the industry are indifferent to the negative image that this generates in the minds of much of the potential consuming public. Admittedly, such advertising works. But marketing based on the healthful and tasteful properties of hemp food products, the durable nature of hemp textiles, and the environmental advantages of the crop has proven to be widely acceptable, and is likely to promote the long term development of hemp industries.
Some immediate undesired side effects include a decrease in short-term memory, dry mouth, impaired motor skills and reddening of the eyes.[50] Aside from a subjective change in perception and mood, the most common short-term physical and neurological effects include increased heart rate, increased appetite and consumption of food, lowered blood pressure, impairment of short-term and working memory,[51][52] psychomotor coordination, and concentration.

Thanks Donna, for great share! I use cbd oil every day. I refuse to go without it. I have no arthritic pain at all anymore. I had a hip replacement 3 years ago. I am in need of the other one to be replaced. I was laying awake crying at night because of my hip pain. After I started using the oil my hip has quit aching. I sometimes forget I even have a problem with it or my arthritis. Had I known about the oil before I had my hip replaced I never would have had the surgery. I am pain free. I use hemp oil. There are 20 mg of cannabiniol in each 1 ml dose https://cbdreamers.com/cbd-oil-for-pain
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